A5066271230- Cardiovascular Disease and Adiposity
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Healthcare Systems and Public Health
- Blood Pressure and Hypertension Studies
- Vitamin D Research Studies
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- COVID-19 Clinical Research Studies
- Pharmaceutical Practices and Patient Outcomes
- Pneumonia and Respiratory Infections
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Venous Thromboembolism Diagnosis and Management
- Respiratory viral infections research
- Influenza Virus Research Studies
- Chronic Disease Management Strategies
- Neurological Disorders and Treatments
- Vascular Procedures and Complications
- Diagnosis and Treatment of Venous Diseases
- Protease and Inhibitor Mechanisms
- Long-Term Effects of COVID-19
- Heparin-Induced Thrombocytopenia and Thrombosis
- Human Health and Disease
- Cancer Treatment and Pharmacology
Ural State Medical University
2017-2025
Introduction . Arterial hypertension (AH) is the most common chronic non-communicable disease, especially among individuals over 60 years old, where its prevalence exceeds 60%. The relationship between blood pressure (BP) levels and risk of cardiovascular events observed across all age groups. aim study was to assess adequacy antihypertensive therapy in outpatient multimorbid patients different Materials methods included 323 with verified AH (92 men 231 women). Patients were divided into...
Background. Cardiovascular diseases, including arterial hypertension (AH), annually claim 17 million lives, of which 9.4 are associated with AH. About 40% the adult population suffers from this disease. Genetic polymorphisms renin-angiotensin-aldosterone system play a significant role in its development and response to therapy. Studying candidate genes responsible for implementation RAAS mechanisms will optimize choice antihypertensive therapy physicians at initial stages AH future....
Introduction . Myocardial remodeling is a consequence or predictor of several cardiovascular diseases. The key process in myocardial the degradation collagen fibers, mediated by activity matrix metalloproteinases and their tissue inhibitor. aim this study was to evaluate serum levels metalloproteinase type 9 inhibitor 1 female patients with arterial hypertension, remodeling, diastolic dysfunction. Materials methods A cross-sectional that included 84 postmenopausal women. All underwent...
В обзоре анализируются современные представления о структурно-функциональных особенностях интегринов у человека; исследования связи между полиморфизмом гена T1565C, кодирующего интегрин бета‑3 (ITGβ3), тромботических явлений и эффективностью применяемых антитромбоцитарных препаратов; рассмотрена целесообразность на наличие данного полиморфизма. Анализ проведен основе публикаций, представленных в базах данных web-ресурсах: MEDLINE, PubMed, Google Scholar, Cyberleninka, электронной библиотеке...
Aim . Assessment of the level and structure polymorbidity, features pharmacotherapy therapy in patients different age groups, belonging to category high extremely cardiovascular risk, observed outpatient clinics. Material methods The single-stage study included 282 very risk who were divided into three groups: (1) 45-59 years, (2) 60-74 (3) ≥75 years. polymorbidity groups evaluated. frequency polypragmasia was determined, treatment adequacy over 65 years analyzed using STOPP / START criteria...
Aim. To reveal the features of structural-geometric remodeling left chambers heart, diastolic function ventricle and to assess presence calcification valvular structures heart in late postmenopausal women with different levels vitamin D. Material methods. The cross-sectional study included 123 women. A standard transthoracic echocardiography was performed an assessment morphometric variants its according transmitral flow. significance differences assessed using Mann–Whitney test, χ 2...
Aim . To investigate the prevalence and characteristics of polyvascular disease in Eurasian region's population with one or more previously established locations atherosclerotic arterial damage, to evaluate diagnostic importance ankle-brachial index (ABI) as a marker for (PVD). Material methods A total 1837 patients were included main branch KAMMA registry (patients PVD), among which 91,6% had coronary artery (CAD) (n=1683). For further analysis, group CAD was combined 1222 second —...
Aim. To study the clinical status and data of laboratory instrumental examination patients with non-obstructive ischemic heart disease (IHD) multifocal atherosclerosis (MFA) included in KAMMA registry. Material methods. The subanalysis 1,893 IHD who underwent coronary angiography (CAG) ultrasonic peripheral arteries. Based on CAG data, were divided into two groups: group 1, obstructive (CA) (maximum stenosis ≥50% and/or history percutaneous intervention/coronary artery bypass grafting,...
Aim. To study clinical profile and antihypertensive treatment features in outpatients observed ambulatory facilities. Material methods. 140 arterial hypertension (AH) were examined, questioning anthropometry performed. Blood pressure (BP) was measured on both hands, then twice the hand with larger value, medium value calculated. Tests results obtained from outpatient cards. Results. The sampling included 100 (71.4%) females 40 (28.6%) males. Median of systolic BP at first measurement 140.0...
Introduction. Acute respiratory distress syndrome (ARDS) and cardiovascular events, acute myocardial injury being the most frequent of latter, are among leading causes death in COVID-19 patients. The lack consensus on pathogenesis mechanisms, patients management, treatment an rehabilitation logistics, anticoagulant identified SARS-CoV-2 or suspected setting indicates need to assess, analyze summarize available data issue. Materials methods. Scientific publications search was carried out...
BACKGROUND : The global prevalence of vitamin D deficiency is currently a real threat due to association with major chronic non-communicable diseases. Abdominal obesity, hypertension, dyslipidemia, and hyperglycemia contribute significantly cardiometabolic risk in late postmenopausal women. AIM assess the frequency insufficiency 25(OH)D residents Yekaterinburg; establish associations serum concentration components metabolic syndrome severity menopausal symptoms. MATERIALS AND METHODS During...
OBJECTIVE: To identify diastolic myocardial function features in late postmenopausal women with polymorphic variants of the integrin beta-3 (ITGB3) gene and arterial hypertension.
 MATERIALS AND METHODS: This cross-sectional study enrolled 97 women, a median age 67 (6570) years. The duration menopause was 18 (1621) Molecular genetic studies to assess ITGB3 (rs5918) T1565C polymorphism were performed. participants homozygous TT variant comprised group 1, whereas 2 included patients C...
Background: Cardiovascular complications of COVID-19 result in challenges for differential diagnosis, patients referral and treatment, which negatively affect the outcomes.
 Aim: To identify clinical particulars various types acute coronary syndrome course with COVID-19.
 Materials methods: This retrospective cross-sectional study included 202 (ACS) admitted to a primary vascular medicine center from September December 2020. Their medical records were used analysis ACS course,...
Цель работы. Оценить взаимосвязь недифференцированной дисплазии соединительной ткани и атеросклероза брахиоцефальных артерий у женщин постменопаузального периода. Материалы методы. Одномоментное исследование 120 женщин, медиана возраста – 68 (65-70) лет, продолжительность постменопаузы 18 (16-21) лет. Проведено ультразвуковое дуплексное сканирование экстракраниальных отделов брахиоцефальной зоны. Нормальной толщиной комплекса «интима медиа» признавались значения < 0,9 мм, увеличение...
Цель. Оценить частоту выявления полиморфных маркеров гена бета-субъединицы рецептора фибриногена тромбоцитов (ITGB3) среди женщин постменопаузального периода, проживающих в Свердловской области.
Aim . To assess myocardial diastolic function (DF) in late postmenopausal women with undifferentiated connective tissue disease (UCTD) and hypertension (HTN). Material methods This cross-sectional study included 135 women, the median age of which was 68 years (65÷70,5 years). The anamnesis collected using a standardized questionnaire. Verification UCTD carried out according to clinical guidelines. All patients underwent standard transthoracic echocardiography. assessment left ventricular...