L. Manfrè

ORCID: 0000-0001-7314-2294
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Musculoskeletal pain and rehabilitation
  • Pelvic and Acetabular Injuries
  • Medical Imaging and Analysis
  • Management of metastatic bone disease
  • Meningioma and schwannoma management
  • Facial Nerve Paralysis Treatment and Research
  • Head and Neck Surgical Oncology
  • Hemoglobinopathies and Related Disorders
  • Neurofibromatosis and Schwannoma Cases
  • Advanced Neuroimaging Techniques and Applications
  • Iron Metabolism and Disorders
  • Cerebral Venous Sinus Thrombosis
  • Vestibular and auditory disorders
  • Ear Surgery and Otitis Media
  • Fetal and Pediatric Neurological Disorders
  • Infectious Diseases and Tuberculosis
  • Advanced MRI Techniques and Applications
  • Congenital heart defects research
  • Teratomas and Epidermoid Cysts
  • Glioma Diagnosis and Treatment
  • Cerebrospinal fluid and hydrocephalus
  • Shoulder Injury and Treatment
  • Traumatic Ocular and Foreign Body Injuries

Istituto Neurologico Mediterraneo
2023-2024

Mediterranean University
2022-2024

United States Department of State
2024

Istituto di Studi sul Mediterraneo (CNR - ISMed)
2020-2023

Ospedale Cannizzaro
2005-2023

Advanced Imaging Research (United States)
2022

Statistical Research (United States)
2022

KU Leuven
2022

European Society of Anaesthesiology
2019

Santissima Trinità
2015

The purpose of this study was to evaluate the spectrum MR findings brain in asymptomatic patients affected with thalassemia intermedia or sickle cell-thalassemia disease prevent damage by identifying at risk for stroke so that transfusional pharmacologic treatment could be implemented.Forty-one who were younger than 50 years and minor hemoglobinopathies underwent imaging brain. Ischemic lesions classified as small, medium, large single multifocal. Atrophic changes graded subjectively mild,...

10.2214/ajr.173.6.10584785 article EN American Journal of Roentgenology 1999-12-01

Background Treatment of spinal metastatic lesions by radiofrequency ablation (RFA) before cementation can potentially help in local tumor control and pain relief. This is often limited access location. study reports multicenter clinical imaging outcomes following targeted RFA (t-RFA) cement augmentation neoplastic the spine. Material methods A retrospective 49 patients with 72 painful vertebral lesions, evaluated for was undertaken. Visual Analogue Pain score (VAS) Oswestry Disability Index...

10.1136/neurintsurg-2016-012908 article EN Journal of NeuroInterventional Surgery 2017-04-06

Vertebral augmentation has been used to treat painful vertebral compression fractures and metastatic lesions in millions of patients around the world. An international group subject matter experts have considered evidence, including but not limited mortality. These considerations led them ask whether it is appropriate allow subjective measure pain so dominate clinical decision proceed with augmentation. The discussions that ensued are related below.

10.3390/medicina58101431 article EN cc-by Medicina 2022-10-11

The possibility of increasing Hb F in vivo using drugs like 5-azacy-tidine, hydroxyurea, and butyrate has been established. However, many cases this does not entail an increase total hemoglobin. We report on a patient with Lepore/β-thalassemia being treated hydroxyurea (30 mg/Kg/day) because the presence erythroid extra-medullary masses severe neurological abnormalities. During therapy showed remarkable improvement signs due to reduction masses, significant both hemoglobin (from 5.8 9.7...

10.3109/03630269708997382 article EN Hemoglobin 1997-01-01

From the Istituto di Clinica Oculistica, and †the Radiologia, Universita' Palermo, Italy. RETINA,TM The Journal of Retinal Vitreous Diseases, encourages authors to submit brief reports describing unusual findings, new techniques, instruments. Material submitted for consideration in this section journal is done so with assumption that data provided do not duplicate previously published material has been elsewhere. Each author must sign a disclosure effect (see Instructions Authors complete...

10.1097/00006982-199515050-00012 article EN Retina 1995-01-01

Bone metastases account for 10% to 30% of secondary tumors in all cancer types. In patients with primary hepatocellular carcinoma (HCC), bone are usually treated by nonoperative procedures including pain medication, radiotherapy, hormone therapy, chemotherapy, and bisphosphonates. Surgical treatments include vertebrectomy, reconstruction a cage or polymethylmethacrylate cement, stabilization pedicle screws. Sacroplasty treat from HCC has been rarely reported the literature. We describe case...

10.1177/030089161009600130 article EN Tumori Journal 2010-01-01

Purpose Lumbar spinal canal stenosis and lumbar foraminal are common, degenerative pathologies which can result in neurogenic claudication have a negative impact on function quality of life. Percutaneous interspinous devices (PIDs) recently-developed, minimally-invasive, alternative treatment option. This study details 9 year single-centre experience with PIDs examines the complementary use spinous process augmentation (spinoplasty) to reduce failure rates. Methods A retrospective cohort...

10.1136/neurintsurg-2019-015601 article EN Journal of NeuroInterventional Surgery 2020-01-22

Trigeminal neuralgia and cerebellopontine‐angle lipomas are very rare in children. We describe the history findings of an 8‐year‐old boy with right trigeminal a lipoma detected by magnetic resonance imaging at level root‐entry zone seventh cranial nerve. propose possible mechanism infiltration rootlets lipoma.

10.1046/j.1526-4610.2001.041007720.x article EN Headache The Journal of Head and Face Pain 2001-07-12

Lumbar spinal canal stenosis (LSCS) is one of the most common degenerative diseases in elderly patients. Failure he treatment can occur, generally related to bone remodelling/fracture spinous processes. PMMA augmentation posterior arch (spinoplasty, SP) has recently been proposed case neoplastic involvement. This study evaluated efficacy SP as a prophylactic before introducing an interspinous spacer (IS). Moreover, we consider possibility treat patients who previously underwent IS implants...

10.15274/inr-2014-10052 article EN Interventional Neuroradiology 2014-01-01

Axial microinstability secondary to disc degeneration and consequent chronic facet joint syndrome (CFJS) is a well-known pathological entity, usually responsible for low back pain (LBP). Although posterior lumbar fixation (PIF) has been widely used spine instability LBP, complications related wrong screw introduction, perineural scars extensive muscle dissection leading dysfunction have described. Radiofrequency ablation (RFA) of joints zygapophyseal nerves conventionally treatment fails in...

10.15274/inr-2014-10031 article EN Interventional Neuroradiology 2014-01-01

The prevalence of sacroiliac Joint (SIJ) disease as a cause LBP is considered to range from 21% 25%. Nevertheless, SIJ instability frequently underestimated. Although conventional surgery has been used for several years in an attempt stabilize the SIJ, new percutaneous system proposed articular fusion. Recently “one-step” fixation procedure proposed. We describe case patient with painful treated fully CT-guided technique simple analogue sedation.

10.15274/inr-2014-10049 article EN Interventional Neuroradiology 2014-04-28
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