A5090717909- Growth Hormone and Insulin-like Growth Factors
- Neuropeptides and Animal Physiology
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Veterinary Medicine and Surgery
- Receptor Mechanisms and Signaling
- Mast cells and histamine
- Reproductive Physiology in Livestock
- Regulation of Appetite and Obesity
- Pain Mechanisms and Treatments
- Stress Responses and Cortisol
- Birth, Development, and Health
- Veterinary Pharmacology and Anesthesia
- Animal Nutrition and Physiology
- Neonatal Respiratory Health Research
- Circadian rhythm and melatonin
- Diet and metabolism studies
- Pituitary Gland Disorders and Treatments
- Animal Genetics and Reproduction
- Metabolism and Genetic Disorders
- Bone health and osteoporosis research
- Olfactory and Sensory Function Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Estrogen and related hormone effects
- Adipose Tissue and Metabolism
University of Milan
2016-2025
University of Trieste
1993
Pharmac
1989
Mylan (Switzerland)
1989
University of Pavia
1969
Istituto di Farmacologia Traslazionale
1966
SUMMARY The gonadotrophin-releasing activity of hypothalamo-neurohypophysial hormones has been investigated in normal female rabbits. Pooled urine, obtained before and after intravenous injection different posterior pituitary preparations (Pitressin, Pitocin, lysine-vasopressin synthetic oxytocin), was extracted by the kaolin-acetone method assayed mouse uterus test. All used induced a significant rise release gonadotrophins. experiments suggest that polypeptides may play role physiological...
SUMMARY The effect of cortisol (5 mg./100 g. body weight administered for 10 days) on the secretion growth hormone (GH) from pituitary was studied in 30-day-old female rats. results indicate that suppressive action GH is not due to a reduced availability but an impairment release mechanism(s) as shown by lack response insulin hypoglycaemia and marked decrease GH-releasing activity hypothalamus cortisol-treated
An investigation of the growth hormone-releasing activity hypothalamic extracts from young growing animals and which had reached stasis was undertaken to determine if a different might be present in with advancing age. For this purpose, 30-day-old rats 2-year-old (5 mg/100 g body wt) rat stalk-median eminence region were tested vivo using intracarotid injections into recipient female rats. The pituitaries assayed for hormone content by “tibia test” method. Hypothalamic induced an almost...
The effect of amylin on gastric ulcers induced by oral administration indomethacin (Indo, 20 mg kg −1 at a dosing volume 5 ml) or ethanol 50% (EtOH, 1 ml/rat) was investigated in conscious rats. Amylin given intracerebroventricularly (0.22, 0.66 and 2.2 μg/rat, i.c.v.) demonstrated dose‐dependent cytoprotective against both Indo EtOH‐induced ulcers. In contrast, amylin, subcutaneously doses effective inhibiting acid secretion (2.5, 10 40 μg , s.c), did not show any effect. interaction...
SUMMARY It is shown that anterior pituitary tissue grafted into hypophysectomized rats and lacking any connexion with the median eminence does not retain somatotrophic or gonadotrophic activities, but has some adrenocorticotrophic (ACTH) thyrotrophic (TSH) activities. This conclusion based on: (1) partial maintenance of thyroid adrenal weight; (2) results studies on 131 I uptake TSH concentration in pituitaries; (3) persistence significant responses to Pitressin, lysine-vasopressin...
Despite increasing professionalism in dog breeding, the physiological range of birth weight this species remains unclear. Low can predispose to neonatal mortality and growth deficiencies humans. To date, influence morphotype on has never been studied dogs. For purpose, an Italian census was collected from 3293 purebred pups based maternal morphotype, size, body breed, as well litter size sex pups. Multivariate analysis outcomes showed that (p < 0.001) 0.05) increased with weight. Birth also...
SUMMARY The neurohaemal part of the median eminence rat hypothalamus is characterized by numerous nerve terminals which end near a rich network fenestrated capillaries. An attempt was made to isolate different types means sucrose density-gradient centrifugation. subcellular fractions obtained were assayed for dopamine, noradrenaline and 5-hydroxytryptamine. In addition FSH- GH-releasing activities determined. A sample each fraction taken electron microscopical observations. Dopamine,...
Due to the lack of unequivocal scientific evidence, gonadectomy’s effects on dogs’ behavior are still debated. Since veterinarians differ in their opinion, there may be considerable diversity advice received by owners. This study aimed evaluate gonadectomy dog across time. Ninety-six owners (48 control dogs and 48 experimental dogs) were interviewed twice (T0 T1, nine months later) obtain information about dog’s behavior. No change was found eating or weight both groups. Compared T0, at...
The adverse health effects of both active and passive tobacco smoke have been well-known in humans for a long time. It is presumable that even pets, which intimately share the owner’s lifestyle, may be exposed to same risks. This study aimed detect quantify cotinine (a metabolite nicotine) serum hair dogs using specific commercial ELISA immunoassay kit. A total 32 dogs, 16 unexposed smoke, were enrolled. concentration was higher than group matrices (p < 0.001), with greater values 0.001)....