- Pharmaceutical Practices and Patient Outcomes
- Medication Adherence and Compliance
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical studies and practices
- Mobile Health and mHealth Applications
- Nutrition and Health in Aging
- Hepatitis C virus research
- Orthopedic Infections and Treatments
- Cancer survivorship and care
- Safe Handling of Antineoplastic Drugs
- Anesthesia and Pain Management
- Patient Safety and Medication Errors
- Cancer Treatment and Pharmacology
- Nausea and vomiting management
- HIV/AIDS drug development and treatment
- Surgical site infection prevention
- Heart rate and cardiovascular health
- Multiple Sclerosis Research Studies
- Pediatric Pain Management Techniques
- Pneumocystis jirovecii pneumonia detection and treatment
- Prostate Cancer Treatment and Research
- Frailty in Older Adults
- Nutrition, Genetics, and Disease
- Chronic Lymphocytic Leukemia Research
- Venous Thromboembolism Diagnosis and Management
Hospital General Universitario Gregorio Marañón
2015-2025
We assessed the impact of a pharmacotherapy follow-up programme on key safety points [adverse events (AE) and drug administration] in outpatients treated with oral antineoplastic agents (OAA). performed comparative, interventional, quasi-experimental study OAA Spanish hospital to compare pre-intervention group patients (not monitored by pharmacists during 2011) intervention (prospectively 2013). AE data were collected from medical records. Follow-up was 6 months, 249 included...
Objective: Oral antineoplastic agents (OAA) lead to new challenges in patient education, monitoring, medication errors, drug interactions, adverse events management, and adherence. The aim is develop a structured guide supporting pharmacist interviews onco-hematologic outpatients’ education process identify the key points that should address order increase OAA safety efficacy.Methods: A literature review was performed recommended standards associated with approved by ASCO MASCC were...
Oral antineoplastic agents (OAAs) have revolutionized cancer management. However, they been reported with adverse side effects and drug-drug interactions. Moreover, patient adherence to OAA treatment is critical. Mobile apps can enable remote real-time pharmacotherapeutic monitoring of patients, while also promoting autonomy in their health care.The primary objective was analyze the effect using a mobile app for follow-up patients oncohematological malignancies undergoing OAAs on outcomes....
Objective To design a mobile app based on the needs of onco-hematological patient receiving oral antineoplastic agents. Methods A multidisciplinary working group (pharmacy–oncology–hematology) was created to app. The study developed in three phases: first, we analyzed features patients We then available apps for cancer patients. Finally, designed app's functionalities. Results included 51 with middle-advanced age (68.7 years (SD=10.7)). They were polymedicated (mean: 5.3 (SD = 2.7), numerous...
Background: No previous studies exist examining the effectiveness and safety in real clinical practice of combination ombitasvir/paritaprevir/ritonavir dasabuvir (OBV/PTV/r+DSV). Objective: To evaluate OBV/PTV/r+DSV with or without ribavirin for 12 weeks treatment-naïve previously treated adult patients chronic hepatitis C virus (HCV) genotype 1 infection. Methods: This was an observational study a prospective cohort pretreated who received OBV/PTV/r (25/150/100 mg once daily) DSV (250 twice...
<h3>Objectives</h3> Infection following orthopaedic surgery is a feared complication and an indicator of the quality hospital. Surgical antibiotic prophylaxis (SAP) guidelines are not always properly followed. Our aim was to describe evaluate impact multidisciplinary intervention on adherence hospital 30-day postoperative outcomes. <h3>Methods</h3> The study carried out from January May 2016 consisted creating team, updating institutional embedding recommendations in computerised physician...
What is known and objectives Inadequate management of chronic medication puts patients at risk causes unnecessary suspension surgical procedures. The objective the study was to calculate rate cancellation elective procedures due inadequate medications analyse underlying cancellation. Methods We designed an analytic, observational, retrospective all performed from July October 2017 in a tertiary hospital. main variable percentage surgeries cancelled owing medications. Other variables recorded...
Abstract Purpose Initial experience with use of a smartphone application to enhance communication and home monitoring hematology/oncology patients under treatment oral antineoplastic agents (OAAs) is described. Summary Broad OAAs changing the landscape patient care, this form therapy giving greater autonomy but also raising concerns about correct OAA administration management adverse effects (AEs) or interactions. Information technologies, specifically mobile health are ideal tools in new...
Rationale, aims and objectives Surgical-site infections (SSI) are associated with increases in hospital length of stay hospitalization costs patient’s poor quality life. Eradication S. aureus nasal mupirocin could decrease the incidence SSI by this pathogen. The primary purpose our study was to evaluate before after implementation a decolonisation program orthopaedic patients. Methods A pre-post intervention conducted. multidisciplinary group elaborated implemented standard procedure for...
<h3>Background and Importance</h3> The prevalence of pain in post-operative patients is 88.2%, with moderate to severe 19.6% cases. <h3>Aim Objectives</h3> objective was describe pharmaceutical interventions management the impact on patient-reported admission discharge patient satisfaction. <h3>Material Methods</h3> A prospective interventional study (March-May 2023) hospitalised adult admitted general or trauma surgery carried out. <h3>Outcome measures</h3> patient-perceived (VAS)...
<h3>Background and Importance</h3> 2.5% of operations are cancelled because preoperative medication errors. Pharmaceutical consultations an effective tool in detection prevention these errors, but cost-effectiveness their implementation has not been evaluated. <h3>Aim Objectives</h3> To determine the a pharmaceutical consultation to review correct management patients undergoing surgery. <h3>Material Methods</h3> A retrospective, single-center study was conducted analyze all errors prevented...
Preoperative medication errors can be prevented by screening patients through a preoperative pharmaceutical care consultation. The aim of this study was to analyse the cost-effectiveness implementing such consultation and determine which would benefit most.
Venous thromboembolism (VTE) continues to be a problem in surgical patients, but thromboprophylactic measures are not always implemented. This study aimed evaluate thromboprophylaxis practice patients at our institution by assessing appropriateness during admission and discharge; 60-day clinical outcomes analyzed, finally further interventions discussed for continued improvement.A cross-sectional, observational was conducted undergoing orthopedic abdominal procedures. Initially, the protocol...
in recent years, researching about new oral antineoplastics has progressed while its impact on dietary intake and nutritional status (NS) hasn't developed enough yet.dietary NS assessment patients who start treatment with tyrosine kinase inhibitors (TKI) evaluate them.an observational, prospective-six-months study, which were included starting TKI. The was evaluated by a 24 h record food frequency questionnaire. anthropometric measurements the patient-generated Global Subjective Assessment...
<h3>Background</h3> Oral anticancer agents (OAAs) require self-administration by patients at home, increasing the risk of non-adherence and consequently, costs decreasing overall patient survival. <h3>Purpose</h3> To assess impact a comprehensive pharmaceutical care service on oncology outpatients' adherence. Secondary objectives were to analyse influencing factors compare different adherence tests. <h3>Material methods</h3> A program was developed in 2012. Pharmacist interviews literacy...
<h3>Background</h3> The recent development of highly effective interferon free drug regimens has dramatically changed the therapeutic landscape hepatitis C virus (HCV). An intensive pharmaceutical care programme is necessary, due to their commercialisation, limited available data on effectiveness and safety in clinical practice high cost. <h3>Purpose</h3> Our purpose was evaluate, terms efficiency, pharmacists´ interventions patients starting treatment with new antiviral drugs (NAD)....