- T-cell and B-cell Immunology
- Atherosclerosis and Cardiovascular Diseases
- Viral-associated cancers and disorders
- Immune Cell Function and Interaction
- Nutrition, Genetics, and Disease
- Medical Research and Treatments
- TGF-β signaling in diseases
- Polyomavirus and related diseases
- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- Immunotherapy and Immune Responses
- Diverse Approaches in Healthcare and Education Studies
- Plant Genetic and Mutation Studies
- Lipid metabolism and biosynthesis
- Breast Cancer Treatment Studies
- Plant Molecular Biology Research
- Cancer-related Molecular Pathways
- Biomarkers in Disease Mechanisms
- Cancer-related molecular mechanisms research
- Rice Cultivation and Yield Improvement
- Clinical practice guidelines implementation
- Circular RNAs in diseases
- Cancer-related gene regulation
- Immune cells in cancer
- Estrogen and related hormone effects
Nanchang University
2023-2024
Beijing Red Cross Blood Center
2014-2021
Chinese Academy of Sciences
2017
University of Chinese Academy of Sciences
2017
Institut Pasteur of Shanghai
2017
Second Affiliated Hospital of Harbin Medical University
2015
Harbin Medical University
2010-2015
Qingdao University
2009-2010
Abstract MicroRNAs (miRNAs) are known to play critical roles in regulating rice agronomic traits through mRNA cleavage or translational repression. Our previous study indicated that miR5504 regulates plant height by affecting cell proliferation and expansion. Here, the two independent homozygous mir5504 mutants (CR1 CR2) overexpression lines (OE1 OE2) were further used investigate functions of miR5504. The panicle length, 1000-grain weight grain yield per miR5504-OE identical those...
<i>Objectives:</i> To characterize the specific Epstein-Barr virus (EBV) polymorphisms from nasopharyngeal carcinoma (NPC) patients and healthy donors in Northern China, to explore relationship between EBV genotypes NPC. <i>Methods:</i> The of strains were analyzed by polymerase chain reaction restriction fragment length polymorphism. <i>Results:</i> predominant type was A, C or F both NPC individuals. distributions subtypes not significantly different (p...
Abstract Thymocytes must pass both positive and negative selections to become mature T cells. Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity self-peptide MHC complexes (self pMHC) avoid autoimmune diseases, while ensures the survival maturation of TCRs display intermediate self pMHCs for effective immunity, but whether transcriptional regulation helps conserve positively selected from being purged by remains unclear. Here we show that specific...
Although fibroadenoma is one of the most common types benign breast tumor, genes specific to tumor have not been identified. Microarrays were used identify differentially expressed between and infiltrating ductal carcinoma. The comparative expression identified genes, RAS homolog enriched in brain ( RHEB ), was further explored using reverse transcriptase–polymerase chain reaction (RT‐PCR). Microarray analysis performed on tissue samples from five patients with fibroadenoma. In samples,...
Lung cancer is one of the most malignant tumors worldwide with a high mortality rate, which has not been improved since several decades ago. FOX gene family members have reported to play extensive roles in regulating many biological processes and disorders. In order clarify contribution lung biology, we performed expression profiling analysis from FOXA FOXR cell lines tissue specimens by Real-time PCR, western blot immunohistochemistry analysis. We found that FOXE1 was only over-expressed...
Objective To investigate the effects of group health education under Joint Commission on Accreditation Healthcare Organization (JCI) criteria patients with heart valve replacement (HVR). Methods A total 192 patients, who underwent HVR from February 2013 to January 2014, were selected as sampling and randomly divided into observation (n=96) control by random number table. Patients in given conventional while cases JCI standard, which included outpatient, inpatient, perioperative,...
Objective To investigate the role of histone 4 acetylation in CD28 expression patients with acute coronary syndrome(ACS) by detecting level mRNA and H4 status promoter. Methods CD4+ T cells were isolated magnetic activated cell sorting(MACS). The levels determined real time-PCR after reverse transcription.The promoter regulatory sequences was detected chromatin Immunoprecipitation time-PCR(ChIP-qPCR). Results Compared normal control, CD4+ significantly lowered ACS (Control vs...