- Eosinophilic Disorders and Syndromes
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Bone and Dental Protein Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
- Mesoporous Materials and Catalysis
- Nanoparticle-Based Drug Delivery
- RNA regulation and disease
- Viral gastroenteritis research and epidemiology
- Alcoholism and Thiamine Deficiency
- Circular RNAs in diseases
- CRISPR and Genetic Engineering
- Cancer-related molecular mechanisms research
- TGF-β signaling in diseases
- COVID-19 epidemiological studies
- High Altitude and Hypoxia
- COVID-19 Clinical Research Studies
- Biosensors and Analytical Detection
- Wnt/β-catenin signaling in development and cancer
- Traumatic Brain Injury and Neurovascular Disturbances
- Alcohol Consumption and Health Effects
Romanian Academy
2022-2024
Titu Maiorescu University
2020
Institutul Clinic Fundeni
2020
Cellular Research (United States)
2020
Abstract SARS‐CoV‐2 vaccines are highly efficient against severe forms of the disease, hospitalization and death. Nevertheless, insufficient protection several circulating viral variants might suggest waning immunity need for an additional vaccine dose. We conducted a longitudinal study on kinetics persistence immune responses in healthcare workers vaccinated with two doses BNT162b2 mRNA or without prior infection. No new infections were diagnosed during follow‐up. At 6 months,...
This paper aimed to develop two types of support materials with a mesoporous structure mobile crystalline matter (known in the literature as MCM, namely MCM-41 and MCM-48) load them gallic acid. Soft templating methodology was chosen for preparation structures-the cylindrical micelles certain structural characteristics being formed due hydrophilic hydrophobic intermolecular forces which occur between molecules surfactants (cetyltrimethylammonium bromide-CTAB) when minimal micellar ionic...
BACKGROUNDGastric cancer (GC) remains an aggressive malignancy with a high rate of mortality, being the third leading cause cancer-related death.More than one million newly diagnosed cases and 782685 deaths due to GC were reported in 2018.GC is characterized by limited effective treatment options lack consistent biomarkers for diagnosis prognosis these patients.The discovery new useful early mandatory. AIMTo evaluate potential COL10A1 as circulating biomarker gastric adenocarcinoma patients.
Abstract More than 3 years after the start of SARS‐CoV‐2 pandemic, molecular mechanisms behind viral pathogenesis are still not completely understood. Long non‐coding RNAs (lncRNAs), well‐known players in infections, can represent prime candidates for patients' risk stratification. The purpose current study was to investigate lncRNA profile a family cluster COVID‐19 cases with different disease progression, during initial wave pandemic and evaluate their potential as biomarkers evolution....
Somatic frameshift mutations in exon 9 of calreticulin (CALR) gene are recognized as disease drivers primary myelofibrosis (PMF), one the three classical Philadelphia-negative myeloproliferative neoplasms (MPNs). Type 1/type 1-like CALR particularly confer a favorable prognostic and survival advantage PMF patients. We report an unusual case incidentally diagnosed 68-year-old woman known with hepatitis C virus (HCV) cirrhosis who developed progressive painful splenomegaly, without anomalies...
BCR::ABL1-negative myeloproliferative neoplasms (MPNs) are clonal haematopoietic stem cell disorders characterized by specific driver mutations and an increased risk of both macrothrombosis microthrombosis. Serotonin receptor type 1B (HTR1B) was found to be expressed various solid tumours, also primary bone marrow mononuclear cells from myelodysplastic neoplasm acute myeloid leukaemia patients, representing a potential therapeutic target. In this study we assessed for the first time...
: Introduction In the modern world a pathology with increasing frequency is that of spinal cord injury (SCI), risk dysfunction on multiple levels. Following our clinical experience, we have conducted studies effect hypoxic stress (also present in injury) neuronal cell cultures treated for long time ethanol (trying to reproduce chronic alcoholism). this article behavior neural cells subacutely exposed after stress, order perform comparative analysis exposure alcohol. Materials and methods We...