A5025316362- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Cancer Treatment and Pharmacology
- Cancer Risks and Factors
- Breast Cancer Treatment Studies
- Cancer survivorship and care
- Multiple and Secondary Primary Cancers
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Cancer, Lipids, and Metabolism
- Healthcare Systems and Practices
- Frailty in Older Adults
- HER2/EGFR in Cancer Research
- Health Systems, Economic Evaluations, Quality of Life
- Nutrition, Genetics, and Disease
- Clinical practice guidelines implementation
- Health, Medicine and Society
- Global Cancer Incidence and Screening
- Breast Lesions and Carcinomas
- Chemotherapy-related skin toxicity
- Dietary Effects on Health
- Vascular Tumors and Angiosarcomas
- Lung Cancer Research Studies
- Cancer Diagnosis and Treatment
- Biomedical Text Mining and Ontologies
Hôpital Avicenne
2016-2025
Assistance Publique – Hôpitaux de Paris
2015-2024
Université Sorbonne Paris Nord
2015-2024
Centre de Recherche Épidémiologie et Statistique
2014-2023
Inserm
2013-2023
Université Paris Cité
2013-2023
Conservatoire National des Arts et Métiers
2011-2023
Sorbonne Université
1998-2023
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2017-2023
Equipe de Recherche en Epidémiologie Nutritionnelle
2012-2022
To describe the pathologic characteristics and prognostic factors of primary breast sarcomas (PBSs).We reviewed clinical records slides 83 women with PBS treated in our institution between 1954 1991, a median follow-up 7.8 years. The majority patients had undergone surgical treatment.The main histologic type was malignant fibrohistiocytoma (n = 57). For whole population, 10-year overall survival (OS) disease-free (DFS) rates were 62% 50%, respectively. Fédération Nationale des Centres de...
There is currently little support to understand which pathological factors led differences in tumor texture as measured from FDG PET/CT images. We studied whether heterogeneity using analysis FDG-PET/CT images correlated with prognostic invasive breast cancer.Fifty-four patients locally advanced cancer who had an initial were retrospectively included. In addition SUVmax, three robust textural indices extracted 3D matrices: High-Gray-level Run Emphasis (HGRE), Entropy and Homogeneity studied....
Immunotherapy represents a new therapeutic approach in non-small cell lung carcinoma (NSCLC) with the potential for prolonged benefits. Because of systemic nature and heterogeneity tumoral diseases, as well immune restoration process induced by immunotherapy, assessment efficacy is challenging, role FDG PET not established. We evaluated to monitor NSCLC patients treated checkpoint inhibitor. This was retrospective analysis 28 nivolumab, programmed death 1 (PD-1) blocker. All underwent scan...
Physical activity (PA) but also reduced sedentary behavior may be associated with better prognosis and lower risk of recurrence in cancer patients. Our aim was to quantify the variations PA time spent between before after diagnosis, relying on prospective data French adults. We investigated sociodemographic lifestyle factors these variations.Subjects (n = 942) were incident cases diagnosed NutriNet-Santé cohort 2009 2015. prospectively collected 7-day short version IPAQ questionnaire every...
BACKGROUND Currently, there is no gold standard for the treatment of patients with metastatic breast carcinoma who have experienced failure anthracyclines and taxanes. A biologic rationale suggests that mechanism taxane resistance could be because an excess depolymerized tubulin enhance sensitivity to vinorelbine. The objective study was assess tolerance efficiency weekly vinorelbine in after METHODS Patients measurable disease, a World Health Organization performance status less than 3 life...
Approximately 10% of patients with non-small cell lung cancer (NSCLC) have brain metastases at the time diagnosis. When surgical resection is not possible, whole radiotherapy standard care, a cerebral response rate approximately 30%. We report our experience an upfront association carboplatin and pemetrexed (areas under curve, 5 500 mg/m2, respectively), every 3 weeks, in 30 presenting newly diagnosed NSCLC. Cerebral MRIs were performed 6–9 weeks. The radiologic rates assessed according to...
Neurofibromatosis 1 (NF1) is the most common autosomal dominant disorder, with an incidence of in 2,500-3,300 live births. NF1 associated significant morbidity and mortality because complications, especially malignant peripheral nerve sheath tumors (MPNSTs), which mainly develop during adulthood. We evaluated our experience management MPNSTs by standard chemotherapy anthracycline and/or ifosfamide terms time to treatment failure overall survival.We performed a retrospective review...
Yondelis® (trabectedin, ET-743) is a novel marine-derived anticancer compound found in the ascidian Ecteinascidia turbinata. It currently under phase II/III development breast cancer, hormone refractory prostate sarcomas and ovarian cancer. Activity cancer experimental models has been reported, preliminary evidence of activity this setting during I programme also observed. The present study assessed feasibility trabectedin women with advanced previously treated conventional therapies....
Abstract Background To assess and compare the ability of five mobility indices to predict 6-month mortality in older patients with cancer. Methods All consecutive ambulatory cancer referred for a geriatric assessment before treatment decision were included prospective two-center cohort study (Physical Frailty Elderly Cancer) between 2013 2017. The compared short physical performance battery, gait speed, hand grip strength, one-leg stance balance test, repeated falls. primary endpoint was...