A5031474407- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Diabetic Foot Ulcer Assessment and Management
- Circadian rhythm and melatonin
- Ophthalmology and Eye Disorders
- Dermatologic Treatments and Research
- Traumatic Brain Injury Research
- Neurosurgical Procedures and Complications
- Peripheral Neuropathies and Disorders
- Opioid Use Disorder Treatment
- Streptococcal Infections and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Hereditary Neurological Disorders
- Injury Epidemiology and Prevention
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Pressure Ulcer Prevention and Management
- Disaster Response and Management
- Trigeminal Neuralgia and Treatments
- Leprosy Research and Treatment
- Adrenal Hormones and Disorders
- Steroid Chemistry and Biochemistry
- Infectious Diseases and Tuberculosis
The University of Texas Medical Branch at Galveston
2022-2025
The study investigated the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on burn-induced coagulopathy in severely burned patients. Patients with a greater than 20% TBSA were identified TriNetX research network and categorized into receiving or not NSAIDs first week after burn. statistical significance rate coagulopathy, mortality sepsis following injury was analysed. We observed 837 patients taking NSAIDS during burn 1036 without. After matching for age, gender race, risk...
Studies conflict on the significance of burn-induced coagulopathy. We posit that coagulopathy is associated with injury severity in burns. Our purpose was to characterize profiles burns and determine relationships between % total burn surface area (TBSA) burned using International Normalized Ratio (INR). Burned patients INR values were identified TriNetX database analyzed by %TBSA burned. Patients history transfusions, chronic hepatic failure, those anticoagulant medications excluded....
Introduction: Oculogyric crisis (OGC) is a dystonic movement disorder of varying durations that manifests as bilateral paroxysmal upward eye deviation accompanied by involuntary blinking, tongue protrusion, and autonomic symptoms. Separately, septo-optic dysplasia (SOD) congenital involving hypoplasia the optic nerve well hypothalamic pituitary abnormalities. In presented case, we report case OGC in setting SOD with proposed pathogenesis. Case Presentation: A 27-year-old female history...
Background: Diabetic patients often present with complex limb pathology, resulting in impaired sensation the distal extremities making tactile injuries such as burns difficult to notice. We posit that poorly controlled diabetes mellitus, evidenced by increasing elevations hemoglobin A1c, is associated delayed wound healing and increased complications burn patients. Methods: The TriNetX Network, a database of 89 million across U.S., was queried for diabetic foot ankle burns. Patients were...
Hunt, Patrick J. PhD; Keys, Phillip H. BS; Dalal, Sujata Boardman, Dale Davila-Siliezar, Pamela MD; Laylani, Noor Al-Zubidi, Nagham Lee, Andrew G. MDEditor(s): Avery, Robert DO; Golnik, Karl C. Froment, Caroline MD, Wang, An-Guor MD Author Information
Abstract Introduction In lieu of outdated and limited patient studies on excision for severe burns, a more comprehensive analysis is indicated to determine the effects early skin following burn. This study aims address outcomes excision. Methods Data collection was performed using TriNetX, national research database. The population included patients ranging from 0 90 years old who underwent burns. Groups were stratified by number days after injury in which they received treatment. Five...
Lymphocytic hypophysitis (LH) is a primary inflammatory disorder of the pituitary gland and infundibulum that commonly manifests in both mass effect endocrinologic symptoms. Although exact pathophysiology remains unclear, it has been increasingly linked to an autoimmune process. Complications arise by two separate mechanisms. Inflammation sella can lead headaches visual field defects. Pituitary inflammation and, chronically, fibrosis interfere with gland’s hormone-secreting capacity, often...
Abstract Introduction Despite advancements in burn care, the optimal treatment to prevent or treat hypertrophic scars is still elusive. Therefore, objective of this study compare efficacy five glucocorticoid medications commonly used scarring burned patients using a large patient database. Methods Patients diagnosed with scarring, disorders skin, scar conditions and fibrosis skin at least one day after injury were identified TriNetX Hydrocortisone, methylprednisolone, dexamethasone,...
Abstract Introduction Prior studies explored neuropsychological disorders in the context of burn severity; however, relationship between occurrence after and sleep has not been investigated. This study aims to determine if patients that developed a first-time disorder injury are more likely develop psychological or nervous system within 10 years injury. Methods We identified on TriNetX database, federated research network de-identified patient data. formed two groups, those with first time...
Abstract Introduction The risk of coagulopathy is increased in severe burns. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed burn patients to relieve pain and reduce inflammation. This study investigates the impact NSAIDs on induced severely burned patients. Methods Severe (total body surface area [TBSA] >20%) were identified with TriNetX, a North American federated health research network from 51 health-care organizations (HCOs) categorized for those receiving...
Abstract Introduction Burn injuries place patients in a compromised state, especially those with pre-existing comorbidities. The presence of cancer complicates care and worsens outcomes for suffering from illnesses unrelated to burns, such as sepsis. Therefore, we posit the incidence burn injury on preexisting diagnoses results an increased risk complications. Methods Burned were identified using TriNetX database, global federated health research network. Fifty-one thousand diagnosis prior...
Abstract Introduction The pathophysiological response to major trauma has gender dimorphism in outcomes associated with sex hormones levels. However, little is known of the effects female on burn patients. Previous studies demonstrated exogenous estrogen alleviates hyper-inflammation after burn. We thus posit that patients have fewer comorbidities depending hormone had two objectives: investigate role and potential protective properties treatment burned post-menopausal women. Methods This...
Abstract Introduction The use of opioids in the medical field has contributed to growing opioid epidemic. Nonetheless, remain imperative treatment for pain management burns. While some studies have addressed surgery, a comprehensive analysis pattern burns not been investigated. This study aims identify trends and investigate risk related disorders burn patients. Methods Data was obtained from TriNetX, national research database that provides records de-identified population includes patients...
Abstract Introduction Bacterial infections are a leading cause of complications in burn patients. However, ambiguity remains around the most common infectious etiologies and their resulting complications. Our study identifies which bacterial will lead to specific tracks infection rates these bacteria over time. Methods Burn patients diagnosed with within 6 months were identified TriNetX database using ICD-10 codes; those prior injury excluded. Occurrence following outcomes 12 compared for...
Abstract Introduction Hypertension (HTN) is a prevalent condition in the United States and leads to an increased risk of developing other comorbidities. However, impact hypertension following severe burns on patient outcomes not known. We hypothesize that post-burn associated with comorbidities mortality. Methods This study used data from TriNetX, global federated health research network. Burned patients who were diagnosed essential at least 1 day after injury identified TriNetX database...
BACKGROUND Microvascular decompression is an effective treatment strategy for trigeminal neuralgia. However, there may be inadvertent complications involving adjacent cranial nerves during or months after the operation. This case lesson highlights potential manifestations, both optical and nonneurologic (monocular) binocular diplopia, microvascular in two patients. Neurosurgeons should recognize monocular versus causes of diplopia neurosurgical decompression. OBSERVATIONS The authors...
Patients with sickle cell disease frequently present to the hospital for pain control secondary vaso-occlusive crises (VOCs). Diagnostic challenges exist healthcare providers in distinguishing joint a VOC from an intraarticular infection at initial presentation due lack of established clinical markers exclusive one or other. We 35-year-old female and avascular necrosis bilateral hips right shoulder several previous admissions complaining "different" kind her shoulder. Treated initially...