A5021689770- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Neurological Disorders and Treatments
- Medicinal Plants and Bioactive Compounds
- Neuroscience and Neuropharmacology Research
- Biochemical Acid Research Studies
- Musculoskeletal pain and rehabilitation
- Treatment of Major Depression
- Medicinal Plants and Neuroprotection
- Pain Mechanisms and Treatments
- Pluripotent Stem Cells Research
- Neurogenesis and neuroplasticity mechanisms
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Health and Well-being Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Healthcare professionals’ stress and burnout
- Regulation of Appetite and Obesity
- Nigella sativa pharmacological applications
- Ophthalmology and Visual Health Research
- Anesthesia and Neurotoxicity Research
- Hydrogen's biological and therapeutic effects
- Mental Health Treatment and Access
- Hemispheric Asymmetry in Neuroscience
Ahmadu Bello University
2017-2024
Mood disorders can be considered among the most common and debilitating mental disorders. Major depression, as an example of mood disorders, is known to severely reduce quality life well psychosocial functioning those affected. Its impact on burden disease worldwide has been enormous, with World Health Organisation projecting depression leading cause illness by 2030. Despite several studies subject, little done contextualise condition in Africa, coupled fact that there still much understood...
Depression is a severe disorder that results in poor quality of life and affects hundreds millions worldwide. Research on the relationship between depression oxidative stress has shown important biochemical aspects disease development. Flavonoids are class natural products exhibit several pharmacological properties, including antidepressant-like activity hence, suggested by studies to be exciting prototypes for new antidepressant drugs. Rutin flavonoid glycoside abundantly found plants. The...
Depression is among the most prevalent diseases worldwide. Researchers have identified a link between depression and different types of memory loss, including short term (STM). Also, impairment in function severity. This study was conducted to evaluate effect antidepressant medication on chronic mild stress (CMS) mouse model depression. A total eighteen female mice were randomly divided into three groups six each (n=6). Group I served as normal control, group II exposed CMS for 14 days, III...
<title>Abstract</title> This study investigated the prevalence of academic stress (and associated stressors), anxiety and depression among year two medical students at Ahmadu Bello University, Zaria, Nigeria. Depression, scale-21 (DASS-21) stressor questionnaire (MSSQ) were filled out by 188 randomly selected participants after obtaining their agreement written consent to participate. Preliminary reliability tests on instruments conducted using a few (35) subjects before main data...
Abstract Context: Interindividual variability in pain is modified by interactions of multiple biopsychosocial factors. Though there are reported findings on from studies around the world, relationship between outcomes and anthropometric profiles remains unclear due to conflicting findings. Aim: This study was designed investigate relationships experimental a healthy Nigerian population. Materials Methods: One hundred sixty-one volunteers aged 20 65 years were recruited for study....
Depression affects over 264 million people of all ages globally. Major depressive disorder significantly and chronically reduced quality life by its association with functional impairment both at home in the workplace. Depressive patients consistently complain about cognitive disturbances, exacerbating burden this illness. Several studies have shown that alpha-lipoic acid (ALA) possesses mitochondrial, antioxidant, anti-inflammatory anti-diabetic properties, indicating a basis for evaluating...
This study was carried out to assess the memory enhancing effect of Nigella sativa Extract on mice using Morris Water Maze. The conducted 30 Albino both sexes randomly divided into 5 groups with 6 animals each. Group 1 served as control and treated oral distilled water, Groups 2, 3 4 were orally 1ml/kg, 2ml/kg 4ml/kg body weight (NSE) respectively for days, 100mg/kg drug-Piracetam. Latency locate platform frequency crossing measured. result showed a decrease though not significant in latency...
Depression is a mental disorder characterized by depressive episodes, such as low mood, self-esteem, feeling of guilt, and poor concentration. has high comorbidity with cognitive impairments. Studies have shown that cinnamon anti-inflammatory antiviral, antihypertensive, antioxidant anti-diabetic potentials. Therefore, the aim research was to assess antidepressant effect on open-space forced swim-induced depression in mice. Twenty-five (25) Swiss albino mice were grouped into five groups...
Background: Depression is a severe neurological condition that interferes with the brain neurochemistry and downstream signaling pathways are involved in regulation of mood behavior. Studies have highlighted antidepressant potential GABA mimetics such as Barbiturates Benzodiazepines. Objective: This study investigated activities Phenobarbitone acute chronic mice models depression. Methodology: The experimental animals received single intraperitoneal injection 10mg/kg, 5mg/kg, 2.5mg/kg...