A5019003118- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Autoimmune Bullous Skin Diseases
- Infectious Diseases and Mycology
- Cutaneous lymphoproliferative disorders research
- Drug-Induced Adverse Reactions
- Tumors and Oncological Cases
- Chemotherapy-related skin toxicity
- Microscopic Colitis
- Orthopedic Surgery and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Nail Diseases and Treatments
- Foot and Ankle Surgery
- Hidradenitis Suppurativa and Treatments
- Cell Image Analysis Techniques
- Healthcare Policy and Management
- COVID-19 and healthcare impacts
- Blood disorders and treatments
- Immunodeficiency and Autoimmune Disorders
- Geriatric Care and Nursing Homes
- Gastrointestinal Tumor Research and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Corneal Surgery and Treatments
- bioluminescence and chemiluminescence research
- Hematopoietic Stem Cell Transplantation
Oxford University Hospitals NHS Trust
2019-2025
Churchill Hospital
2016-2021
University of Oxford
2018-2021
Wexham Park Hospital
2015
Stoke Mandeville Hospital
2015
Government Medical College
2014
A high proportion of suspicious pigmented skin lesions referred for investigation are benign. Techniques to improve the accuracy melanoma diagnoses throughout patient pathway needed reduce pressure on secondary care and pathology services.To determine an artificial intelligence algorithm in identifying dermoscopic images taken with smartphone digital single-lens reflex (DSLR) cameras.This prospective, multicenter, single-arm, masked diagnostic trial took place dermatology plastic surgery...
Linked Comment:Lee. Br J Dermatol 2019; 181:10–11. Plain language summary available online
Skin conditions are common in adolescence and impart considerable psychological burden. The Department of Health has identified the specialized needs adolescents transitioning from paediatric to adult services as a priority, yet there few dedicated transitional clinics UK providing appropriate psychosocial support. We have established monthly Teenage Young Adult (TYA) dermatology clinic managing teenagers young adults with skin disease alongside open‐access Demographic data Teenagers'...
Naevus sebaceous (NS) is a congenital cutaneous hamartoma, which typically occurs on the head and neck. Historically, treatment of choice was excision in infancy because potential for malignant transformation; however, recent studies suggest that this risk < 1% unlikely childhood. We sent questionnaire to UK dermatologists plastic surgeons investigate current management practice NS. found almost third still recommend malignancy prevention, while over 90% consider excision, with 64% citing...
The treatment of actinic keratosis (AK) is a potentially effective strategy for the prevention cutaneous squamous cell carcinoma (cSCC). However, patient perspective on potential benefits AK in terms skin cancer reduction has received little attention to date.(i) To investigate preferences topical treatments using discrete-choice experiment (DCE); (ii) evaluate willingness trade between clinical benefit and medical burden.The DCE was conducted as part study establish feasibility phase III...
Abstract Prolonged hospital stay not only increases financial stress on the National Health Service but also exposes patients to an unnecessarily high risk of adverse ward events. Each day accumulates approximately £225 in bed costs with additional risks venousthromboembolism, acquired infections, prescription errors, and falls. Despite being medically fit for discharge (MFFD), awaiting care packages prolonged length (LoS) have poorer outcomes experience increased rates mortality as a...
Gastrointestinal stromal tumours (GISTs) are mesenchymal arising in the gastrointestinal tract. Early detection, before metastasis occurs, is important as complete surgical excision achieves cure. Approximately 85% of GISTs associated with mutations KIT gene, and although majority sporadic, familial have been identified. Several families multiple GIST also described various cutaneous findings including hyperpigmentation, lentigines, vitiligo urticaria pigmentosa. We discuss a 6‐year‐old boy...
Abstract Background Incidence of non‐melanoma skin cancers ( NMSC s) is increasing and can significantly impact on quality life QOL ), yet there are few studies evaluating patient‐reported outcome measures PROM in populations. We undertook a prospective feasibility study to evaluate cancer‐specific , the Skin Cancer Quality Life Impact Tool SCQOLIT patients with new diagnosis . Objectives (i) To establish acceptability dermatology clinics, (ii) descriptive analysis scores Methods Patients...
Enteropathy-associated T-cell lymphoma (EATL) is a rare but potentially fatal cause of diarrhoea and weight loss. EATL commonly presents with abdominal pain, loss, can also present complications such as bowel obstruction perforation. It tumour intraepithelial lymphocytes that occurs in relatively young population. the most common neoplastic complication coeliac disease, occur no prior diagnosis disease. This case demonstrates difficulties be faced diagnosing this disorder, particularly when...
Background. Injuries of the midfoot are often missed and therefore underestimated. Early diagnosis treatment crucial for final outcome. The primary aim this study was to assess pattern results early operative management mid-foot injuries after a midterm follow up. Material methods. This conducted on 25 patients (19 Males, 6 Females ) with mean age 34.6 years (range 18-60 years) fracture dislocations who were admitted consecutively at our centre from May 2008 through November 2010. fulfilling...
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are urgent, serious immune reactions in which there is skin loss severe ulcers the mouth, eyes genital areas. It affects about 5‐6 people per million under 18 years of age U.K. each year. has a mortality (causes death in) 5‐10% re‐occurs up to 18% survivors. The British Association Dermatologists led group relevant experts examine evidence developing guidelines aid diagnosis management SJS/TEN children young people. As with...
Retrospective review data from 183 patients with psoriasis and/or hidradenitis suppurativa a UK tertiary dermatology centre, suggests biologic therapy does not confer significant increased risk of contracting severe Covid-19 in this cohort. This is line growing body evidence which indicates that it safe to continue using therapies during the pandemic.
A 6 month old boy presented with flushing episodes associated facial swelling and agitation. 3 cm × 1 tanned erythematous lesion …
Actinic keratoses are rough patches of skin caused by years sun damage. There is a small risk that AK could progress into form cancer called cutaneous Squamous Cell Carcinoma (cSCC). Treatment might therefore provide an effective strategy for cSCC prevention, although this theory has not been rigorously tested. Also, the patient perspective on potential benefits treatment in terms reduction received little attention to date. Treatments include freezing with liquid nitrogen (cryotherapy),...
斯蒂文斯‐约翰逊综合征 (SJS) 和中毒性表皮坏死松解症 (TEN) 是一种紧迫的、严重的免疫反应,它们可能会引起口腔、眼睛和生殖器部位的皮肤脱落和严重溃疡。在英国,每年每 1 百万 18 岁以下的人群中就有 5‐6 人受到这种疾病的影响。它的死亡率(导致死亡的)为 5‐10%,而幸存者中的复发率高达 18%。 英国皮肤科医师协会领导了一组相关专家,在制定帮助儿童和年轻人诊断和管理 SJS/TEN 的指南的过程中,对这些证据进行了研究。就像许多罕见的情况一样,很少有对比两种治疗方法的高质量的试验。大多数证据来自医学文献(即医学期刊)中报道的患者实例。 本研究揭示了儿童和成人在 的病因和转归方面的一些重要差异。感染在儿童和年轻人中是一个更常见的原因,而药物治疗可能是所有年龄段的原因。儿童死于 的可能性比成人小。预防长期并发症至关重要。 早期阶段的管理应确保识别病因,停止可能是病因的任何可能的药物治疗,并考虑感染作为触发因素。改善转归的最佳证据是在适当的临床环境中提供的良好支持性护理。这需要入住有皮肤脱落管理经验的适当专科病房,以及一个能够处理所有潜在临床并发症的医院专家团队。...
This is a cutaneous phototoxic reaction in man his early 80s (fig 1). Fig 1 He started taking pirfenidone for idiopathic pulmonary …
Abstract: Cutaneous reactive angiomatoses encompass a spectrum of conditions driven by underlying occlusive vasculopathy. We present 2 cases angioproliferation in the context end-stage renal failure (ESRF) manifesting as painful cutaneous ulceration. The first case demonstrates histologic features diffuse dermal angiomatosis. second illustrates nonspecific pattern vascular proliferation which does not conform to any classically described subtypes, therefore reinforcing concept...