A5012569865- Cutaneous Melanoma Detection and Management
- Brain Metastases and Treatment
- Nonmelanoma Skin Cancer Studies
- Glioma Diagnosis and Treatment
- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Pelvic and Acetabular Injuries
- Skin Protection and Aging
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Abdominal Surgery and Complications
- Bone fractures and treatments
- Medical Imaging Techniques and Applications
- Reconstructive Surgery and Microvascular Techniques
- Cutaneous lymphoproliferative disorders research
- Lung Cancer Research Studies
- Trauma and Emergency Care Studies
- Body Image and Dysmorphia Studies
- Abdominal Trauma and Injuries
- Healthcare cost, quality, practices
- Surgical site infection prevention
- Botulinum Toxin and Related Neurological Disorders
- Diabetic Foot Ulcer Assessment and Management
- Pressure Ulcer Prevention and Management
Salisbury NHS Foundation Trust
2023-2025
Health Data Research UK
2022-2025
Stoke Mandeville Hospital
2022-2025
Salisbury University
2024
Salisbury District Hospital
2023-2024
Buckinghamshire Healthcare NHS Trust
2021-2023
University of Zurich
2021-2023
University Hospital of Zurich
2018-2022
University of Oxford
2022
Spital Lachen
2022
Abstract Background Keratinocyte cancers (KCs) are the most common type of cancer in White population worldwide, with associated high healthcare costs. Understanding epidemiological trends for KCs, namely basal cell carcinomas (BCCs) and cutaneous squamous (SCCs), is required to assess burden disease, project future identify strategies addressing this pressing global health issue. Objectives To report BCC SCC incidence, mortality disability-adjusted life-years (DALYs). Methods An...
Purpose: Stereotactic radiosurgery (SRS) is the preferred primary treatment option for patients with a limited number of asymptomatic brain metastases. In case relapse after initial SRS optimal salvage not well defined. Within this retrospective analysis, we investigated feasibility repeated courses to defer Whole-Brain Radiation Therapy (WBRT) and aimed derive prognostic factors patient selection. Material Methods: From 2014 until 2017, 42 197 metastases have been treated multiple at our...
Background: This study aimed to explore the hypothesis that stage of breast cancer at initial diagnosis in 2020 is more advanced compared with 2019. Methods: Tumor, node, metastasis and Union for International Cancer Control (UICC) stages new diagnoses Bucks Breast Unit from May 2019 October were reviewed. A p < 0.05 was considered significant. Results: Average UICC increased 1a 2a (p 0.01). Excluding cancers detected through screening, still 1b = 0.0184). There a significant increase...
Abstract Background Cutaneous melanoma (CM) is the leading cause of skin cancer mortality with associated high healthcare costs. Up‐to‐date reporting epidemiological trends for CM required to project future trends, assess burden disease and aid evaluation new diagnostic, therapeutic preventative strategies. Objectives To describe in mortality, incidence, mortality‐to‐incidence indices (MIIs) disability‐adjusted life years (DALYs) over last three decades. Methods A population‐based...
Abstract Background Psoriasis is a disease that often requires prolonged systemic treatment. It important to determine the safety of available therapies. There currently little insight into sex‐specific differences in psoriasis Objectives To examine real‐world, long‐term therapies with sex stratification drug‐related adverse events (ADRs). Methods Ten‐year data from adults moderate‐to‐severe requiring treatment (conventional [CST], biologics) were obtained Swiss registry (SDNTT). ADRs...
Aims The Manchester-Oxford Foot Questionnaire (MOxFQ) is an anatomically specific patient-reported outcome measure (PROM) currently used to assess a wide variety of foot and ankle pathology. It consists 16 items across three subscales measuring distinct but related traits: walking/standing ability, pain, social interaction. the most PROM in UK. Initial MOxFQ validation involved analysis 100 individuals undergoing hallux valgus surgery. This project aimed establish whether individual’s...
Free tissue transfer (FTT) for reconstruction of diabetic foot disease (DFD) is an emerging field to preserve the lower limb within this patient group. The design future quantitative research and clinical services in area must consider needs, expectations concerns patients. This qualitative study explores experiences FTT DFD.
To assess trends in abdominal aortic aneurysm (AAA) hospital admissions, interventions, and related mortality England, to examine the impact of endovascular repair on for years 1998 - 2020.
Journal Article Trends in the mortality, incidence, and disability-adjusted life-years of intestinal obstruction paralytic ileus: observational study Global Burden Disease database Get access Dominic W Proctor, Proctor Department Major Trauma, Imperial College Healthcare NHS Trust, London, UK Correspondence to: W. St Mary's Hospital, Praed Street, London W2 1NY, (e-mail: dom.william.proctor@gmail.com) https://orcid.org/0000-0003-0654-3420 Search for other works by this author on: Oxford...
Appendicitis places a substantial burden on healthcare systems, with acute appendicitis alone being the most common abdominal surgical emergency worldwide. Further characterisation of disease in EU15+ countries may help optimise distribution resources. The aim this observational study was to assess trends mortality, incidence and disability-adjusted life-years (DALYs) across European Union (EU) 15+ between years 1990 2019, Supplemental Digital Content 3, http://links.lww.com/JS9/A589...
Abstract Background Intestinal obstruction and paralytic ileus place a substantial burden on global healthcare systems despite its aetiology often being amenable to preventative interventions. Further characterisation of the disease in EU15+ countries may help optimise delivery services. This observational analysis assessed trends mortality incidence intestinal European Union (EU) 15+ between years 1990 2019. Methods Sex-specific age-standardised rates (ASMRs), (ASIRs) disability-adjusted...
Background The Manchester-Oxford Foot Questionnaire (MOxFQ) is a condition specific patient reported outcome measure (PROM) for foot and ankle surgery. It consists of 16 items across three subscales measuring distinct, but related traits: walking/standing ability, pain, social interaction. Although it the most used PROM in UK, initial MOxFQ validation involved analysis only 100 individuals undergoing hallux valgus This project aimed to establish whether an individual's response varies with...
Objective: The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) benign gallbladder biliary diseases across high-income countries between 1990 2019. Background: Benign place a substantial burden on healthcare systems countries. Accurate characterization disease may help optimize policy resource distribution. Materials methods: Age-standardized incidence rates (ASIRs), age-standardized mortality (ASMRs), DALYs data...
Introduction: Breast cancer diagnosis and treatment have been affected by the COVID-19 pandemic. The aim of study was to explore hypothesis that stage presentation at initial in 2020 is more advanced compared 2019. Methods: New breast diagnoses Bucks Unit from August-October 2019 were reviewed. Electronic records used extract TNM classification UICC combined stage. Patients with incomplete staging information excluded. Pathological if available primary surgery clinical otherwise....
Abstract Introduction Pelvic fractures (PF) are relatively uncommon but account for approximately 3% of all skeletal injuries. We aimed to assess the burden PFs across high health expenditure countries by describing trends in PF incidence rates over last three decades. Methods Using Global Burden Disease (GBD) Study database, we extracted sex specific age-standardised (ASIRs) from 1990-2019 each 19 European Union (EU) 15+ countries. performed Joinpoint regression analysis characterise...
Botulinum toxin A to the glabella is a popular cosmetic intervention. Functional musculature differences may arise from chronic behavioral adjustment high sun exposure levels, requiring greater doses. This could affect clinical practice globally. study investigated effect of climate on real-world