Claudia Leonardi

ORCID: 0000-0001-7603-8820
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About
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Research Areas
  • Total Knee Arthroplasty Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Bone fractures and treatments
  • Orthopaedic implants and arthroplasty
  • Scoliosis diagnosis and treatment
  • Orthopedic Surgery and Rehabilitation
  • Infective Endocarditis Diagnosis and Management
  • Hip and Femur Fractures
  • Spinal Fractures and Fixation Techniques
  • Obesity, Physical Activity, Diet
  • Orthopedic Infections and Treatments
  • Knee injuries and reconstruction techniques
  • Trauma and Emergency Care Studies
  • Urban Transport and Accessibility
  • Spine and Intervertebral Disc Pathology
  • Anesthesia and Pain Management
  • Smoking Behavior and Cessation
  • Diversity and Career in Medicine
  • Health disparities and outcomes
  • Colorectal Cancer Surgical Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Elbow and Forearm Trauma Treatment
  • Global Cancer Incidence and Screening
  • Pelvic and Acetabular Injuries
  • Diverticular Disease and Complications

Louisiana State University Health Sciences Center New Orleans
2016-2025

Louisiana State University
2009-2022

Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2022

Maria Cecilia Hospital
2022

University of Liège
2019-2022

Shaheed Rajaei Cardiovascular Medical and Research Center
2022

PC Krause & Associates (United States)
2021

Indiana University – Purdue University Indianapolis
2019

Indiana University Indianapolis
2019

University of Mississippi
2019

To determine time spent on the working day in sleep, work, sedentary behaviors, and light-, moderate-, vigorous-intensity behaviors by occupation intensity.

10.1097/jom.0b013e31823c1402 article EN Journal of Occupational and Environmental Medicine 2011-11-19

Abstract The effects of heat and UV exposure on the degradation free α‐tocopherol (oil form), dissolved in methanol, hexane were measured. Results showed that due to followed first order kinetics, with samples held at 180 °C showing greatest rate. Free degraded faster high temperatures than α‐tocopherol. In contrast, did not degrade when exposed light for as long 6 h, but methanol significantly a matter time. by 20 70%, respectively over this time span. A mechanism was proposed explain...

10.1007/s11746-009-1411-6 article EN Journal of the American Oil Chemists Society 2009-06-20

Triple Negative Breast Cancer (TNBC) is an aggressive, heterogeneous subtype of breast cancer, which more frequently diagnosed in African American (AA) women than European (EA) women. The purpose this study to investigate the role social determinants racial disparities TNBC. Data on Louisiana TNBC patients 2010-2012 were collected and geocoded census tract residence at diagnosis by Tumor Registry. Using multilevel statistical models, we analyzed neighborhood concentrated disadvantage index...

10.3389/fpubh.2019.00018 article EN cc-by Frontiers in Public Health 2019-02-18

Background and Objectives: Most studies based on self-reported data indicate that female patients more often than males have a same-gender preference for their primary care physician (PCP). Because preferences may not reflect true preferences, we analyzed objective to investigate patients’ PCP gender. Methods: Analyses were performed 2192 new seen within university-based healthcare system by 13 PCPs (2 male, 11 female) during 2017. New asked about gender when assigned PCP. We compared the...

10.1177/2150132720967221 article EN cc-by-nc Journal of Primary Care & Community Health 2020-01-01

The authors review their experiences with perioperative infection markers.

10.60118/001c.125124 article EN Journal of Orthopaedic Experience & Innovation 2025-02-12

The physiochemical properties, controlled release characteristics, stability and cellular uptake of chitosan (Chi)/poly(D,L-lactide-co-glycolide) (PGLA) PLGA particles with entrapped α-tocopherol were investigated to understand the behavior these nanoparticles in GI tract.Chi/PLGA stabilized by lecithin synthesized fully characterized for oral gastrointestinal delivery via transmission electron microscopy, dynamic light scattering, high-performance liquid chromatography fluorescence...

10.2217/nnm.11.44 article EN Nanomedicine 2011-06-28

Patient expectations and demographics are vital factors in determining patient satisfaction outcomes from total knee arthroplasty (TKA). This study was a retrospective chart review that analyzed data TKA patients to determine the impact of age on patient-reported measures following TKA. Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) Oxford scores were collected as primary outcome 356 consecutive who underwent further divided into pain function subscores. Patients...

10.1055/s-0037-1605557 article EN The Journal of Knee Surgery 2017-08-25

BACKGROUND Traumatic hemorrhage from pelvic fractures is a significant challenge, and angioembolization has become standard. Optimal treatment undefined in two clinical scenarios. The first the presence of negative angiogram. Can arterial embolization treat venous bleeding by decreasing pressure head? If angiogram positive, nonselective (NSE) or selective (SE) better? purpose this study to determine if after aids control when which level superior? METHODS A multicenter retrospective review...

10.1097/ta.0000000000001554 article EN Journal of Trauma and Acute Care Surgery 2017-05-02

Adolescent idiopathic scoliosis (AIS) has evidence-based, nonoperative treatments proven to be effective with early diagnosis and prompt treatment. The purpose of this study was identify potential disparities in access treatment for AIS. Specifically, we sought determine the interaction socioeconomic factors on a major curve magnitude recommend at initial presentation.A retrospective review AIS patients who underwent surgery single tertiary pediatric hospital between January 1, 2013 December...

10.1097/bpo.0000000000002213 article EN Journal of Pediatric Orthopaedics 2022-07-19

Itraconazole and coumarin-6 loaded polylactic-co-glycolic acid-nanoparticles (PLGA-ITZ- PLGA-C6-NPs) were synthesized tested for fungal cell uptake antifungal ability based on particle size.PLGA-ITZ- PLGA-C6-NPs using an oil-in-water emulsion evaporation method. Fungal activity of the polymeric NPs was Aspergillus flavus.PLGA-C6-NPs 203 nm associated with surfaces internalized efficiently, while 1206 less efficiently. Antifungal studies PLGA-ITZ-NPs 232, 630 1060 showed differences in...

10.2217/nnm.11.35 article EN Nanomedicine 2011-06-09

Poly(lactic-co-glycolic) acid (PLGA) nanoparticles containing the hydrophobic antifungal itraconazole (ITZ) were developed to address need for more effective means of treating fungal infections.PLGA-ITZ synthesized using an oil-in-water emulsion evaporation method. Nanoparticle morphology (studied by transmission electron microscopy), size zeta potential (dynamic light scattering), encapsulation efficiency (UV-visible spectroscopy), release profile and activity characterized.PLGA-ITZ (of 220...

10.2217/nnm.10.68 article EN Nanomedicine 2010-09-01

Aims & Objectives The purpose of this study was to identify patient characteristics associated with engagement and completion physical therapy (PT) following total knee arthroplasty (TKA) examine the relationship between number PT sessions attended outcomes during first 12 weeks after surgery. Methods Patients underwent unilateral primary TKA by a single surgeon were advised complete 17 over 6 at hospital-affiliated facility. Analyses examined predictors (attendance ≥2 sessions) ± 1...

10.1177/21514593241250149 article EN cc-by-nc Geriatric Orthopaedic Surgery & Rehabilitation 2024-01-01

Abstract Purpose Although back pain is commonly reported in patients with adolescent idiopathic scoliosis (AIS), factors that influence the presence and severity of AIS, including curve-specific variables, have not been well studied. This study aims to describe prevalence AIS determine extent which patient characteristics, factors, are associated a higher risk AIS. Methods The was retrospective medical records review adolescents (aged 10–17 years) diagnosed between 01/01/2018 12/31/2021 at...

10.1007/s43390-024-00904-0 article EN cc-by Spine Deformity 2024-06-23

Purpose: Over the past three decades, Hepatocellular Carcinoma (HCC) is one of few cancers for which incidence has increased in United States (US). It likely social determinants at population level are driving this increase. We designed a population-based study to explore whether neighborhood geographically associated with HCC Louisiana by examining association concentrated disadvantage. Methods: Primary cases diagnosed from 2008 2012 identified Tumor Registry were geocoded census tract...

10.3389/fonc.2018.00375 article EN cc-by Frontiers in Oncology 2018-09-11

Introduction: With the increasing demand for total knee arthroplasty (TKA), rapid recovery protocols (RRPs) have been introduced to reduce costs and length of stay (LOS). Little is known about effects RRPs on postoperative range motion (ROM). Methods: We reviewed medical charts 323 patients who underwent primary TKA performed by a single orthopaedic surgeon at university-based tertiary care safety net practice. Of patients, 129 were treated with standard protocol (SRP) between January 1,...

10.5435/jaaos-d-19-00597 article EN Journal of the American Academy of Orthopaedic Surgeons 2020-02-12
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