A5067252366- Hydrogels: synthesis, properties, applications
- Tendon Structure and Treatment
- Supramolecular Self-Assembly in Materials
- Lipid Membrane Structure and Behavior
- Textile materials and evaluations
- Cellular Mechanics and Interactions
- Plasmonic and Surface Plasmon Research
- Collagen: Extraction and Characterization
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Polysaccharides Composition and Applications
Karlsruhe Institute of Technology
2018-2019
Okinawa Institute of Science and Technology Graduate University
2019
As mechanical properties of cell culture substrates matter, methods for characterization scaffolds on a relevant length scale are required. We used multiple particle tracking microrheology to close the gap between elasticity determined from bulk measurements and elastic sensed by cells. Structure macroporous, three-dimensional cryogel mixtures hyaluronic acid (HA) collagen (Coll) were characterized. Both one-component gels formed homogeneous networks, whereas hybrid heterogeneous in terms...
For the first time, macroporous, elastic, three-dimensional hyaluronic acid cryogels were prepared with genipin as non-cytotoxic crosslinking agent. These are characterized by a lamellar porous structure homogeneous pore size of ~100 µm, shear elasticity ~2 kPa and swelling ratio 2.5 in water. Additionally, multiple particle tracking based microrheology measurements reveal formation heterogeneous network. This novel biomaterial owns great potential alternative for application drug delivery,...