- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Aortic Disease and Treatment Approaches
- Diabetes Management and Research
- Viral Infections and Immunology Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Coronary Interventions and Diagnostics
- Genetic Neurodegenerative Diseases
- Cardiac Structural Anomalies and Repair
- RNA regulation and disease
- Heart Failure Treatment and Management
- Adrenal Hormones and Disorders
- LGBTQ Health, Identity, and Policy
- Sepsis Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- HER2/EGFR in Cancer Research
- Cardiovascular Health and Risk Factors
- Electroconvulsive Therapy Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac electrophysiology and arrhythmias
MedStar Washington Hospital Center
2020-2024
Louisiana State University Health Sciences Center Shreveport
2024
MedStar Georgetown University Hospital
2023
Georgetown University
2023
MedStar Heart & Vascular Institute
2023
University of Azad Jammu and Kashmir
2023
MedStar Union Memorial Hospital
2022
MedStar Health
2021
Research Network (United States)
2021
Sher-i-Kashmir Institute of Medical Sciences
2016-2019
Improving preparticipation screening of candidates for sports necessitates establishing the prevalence high-risk cardiovascular conditions (hr-CVC) that predispose young people to sudden cardiac death (SCD). Our accurate, novel protocol chiefly involved use magnetic resonance (CMR) estimate this prevalence. Middle and high school students from a general United States population were screened by means questionnaires, resting electrocardiograms, CMR determine 3 types hr-CVC:...
Given enough time, transcatheter heart valves (THVs) will degenerate and may require reintervention. Redo aortic valve implantation (TAVI) is an attractive strategy but carries a risk of coronary obstruction.We sought to predict how many TAVIs patients could undergo in their lifetime using computed tomography (CT) simulation.We analysed paired CT scans (baseline 30 days post-TAVI) from the LRT trial EPROMPT registry. We implanted virtual THVs on baseline CTs, comparing predicted...
Background: The supra-annular leaflet position and tall stent frame of the self-expanding Evolut PRO or PRO+ transcatheter heart valves (THVs) may cause coronary occlusion during aortic valve replacement (TAVR)-in-TAVR present challenges for future access. We sought to evaluate risk TAVR-in-TAVR with THVs feasibility Methods: CoreValve Prospective Registry (EPROMPT; NCT03423459) prospectively enrolled patients symptomatic severe stenosis undergo TAVR using a commercially available latest...
Left ventricular assist device (LVAD) therapy improves survival, hemodynamic status, and end-organ perfusion in patients with refractory advanced heart failure. Hospital readmission is an important measure of the intensity LVAD support care. We analyzed readmissions 148 (mean age, 53.6 ± 12.7 yr; 83% male) who received a HeartMate II from April 2008 through June 2012. The had severe failure; 60.1% were Interagency Registry for Mechanically Assisted Circulatory Support class 1 or 2. All...
Background: The LRT trial (Low-Risk Transcatheter Aortic Valve Replacement [TAVR]) demonstrated the safety and feasibility of TAVR in low-risk patients, with excellent 1- 2-year outcomes. objective current study is to provide overall clinical outcomes impact 30-day hypoattenuated leaflet thickening (HALT) on structural valve deterioration at 4 years. Methods: prospective, multicenter was first Food Drug Administration-approved investigational device exemption evaluate patients symptomatic...
Abstract Background The Evolut self‐expanding valve (SEV) systems (Medtronic), were designed to accommodate varying sizes and reduce paravalvular leak (PVL) while maintaining a low delivery profile. These have evolved between product generations, alongside deployment techniques changing over time. Aims: This study aimed examine whether these changes impacted clinical outcomes. Methods EPROMPT is prospective, investigator‐initiated, postmarketing registry of consecutive patients undergoing...
Long-term clinical data on biodegradable-polymer (BP) drug-eluting stents (DES) are limited. The objective of this study was to assess the long-term safety and efficacy BP-DES SYNERGY compared XIENCE V, a durable-polymer (DP)-DES.
Abstract Objectives Evaluate transcatheter heart valve (THV) geometry according to left ventricular outflow tract (LVOT) calcium degree and its impact on hemodynamics outcomes in patients undergoing aortic replacement (TAVR) with a contemporary self‐expanding THV. Background LVOT remains challenging for THVs. location may affect THV deployment flow patterns shear stress, accelerating degeneration. Methods EPROMPT (CoreValve Evolut Pro Prospective Registry; NCT03423459) is prospective,...
Abstract Objectives We sought to report details of the incidence, organisms, clinical course, and outcomes prosthetic valve endocarditis (PVE) after transcatheter aortic replacement (TAVR) in low‐risk patients. Background PVE remains a rare but devastating complication replacement. Data regarding TAVR patients are lacking. Methods performed detailed review all trials who underwent from 2016 2020 were adjudicated have definitive by independent Clinical Events Committee. Results analyzed 396...
Background: Neonatal screening for critical congenital heart disease can aid in early recognition and improved outcome of diseases. Our aim was to assess the performance pulse oximetry as a tool detection diseases asymptomatic neonates.Methods: study hospital based prospective conducted on all neonates brought neonatology section tertiary care hospital. Pulse oximetric performed by single determination postductal oxygen saturation newborns that fulfilled inclusion criteria. To ensure...
Objective: To determine prevalence of adrenal insufficiency in catecholamine-resistent pediatric shock; and to study association between serum cortisol level severity illness catecholamine resistant shock. Study design: Prospective observational Setting: Pediatric intensive care unit a tertiary hospital. Patients: 114 patients with refractory Interventions: Serum outcome parameters mortality, vasoactive inotropic score, Risk Mortality Score mechanical ventilation rate were recorded.Results:...
<p align="justify"><strong>Abstract</strong><strong></strong></p><p align="justify"><strong>Objective</strong><strong>:</strong>  To document association of hyper-glycemia with mortality in septicemic patients.</p><p align="justify"><strong>Methods:</strong><strong> </strong>After approval from departmental review committee, this retrospective comparative study wasÂ...