Maddalena Leongito

ORCID: 0000-0001-7682-8881
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About
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Microbial Inactivation Methods
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Microfluidic and Bio-sensing Technologies
  • Pancreatic and Hepatic Oncology Research
  • Bariatric Surgery and Outcomes
  • 3D Printing in Biomedical Research
  • Genetic and Kidney Cyst Diseases
  • Hernia repair and management
  • Liver Disease Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Pediatric Hepatobiliary Diseases and Treatments
  • Colorectal Cancer Surgical Treatments
  • Gallbladder and Bile Duct Disorders
  • Anorectal Disease Treatments and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Tea Polyphenols and Effects
  • Cardiac, Anesthesia and Surgical Outcomes
  • Body Contouring and Surgery
  • Sarcoma Diagnosis and Treatment
  • MicroRNA in disease regulation
  • Pelvic and Acetabular Injuries
  • Liver Disease and Transplantation
  • Anesthesia and Pain Management
  • Gastroesophageal reflux and treatments

Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2014-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2017-2019

Università degli studi di Cassino e del Lazio Meridionale
2017

Cancer Institute (WIA)
2016

University of Naples Federico II
2010-2013

Federico II University Hospital
2012-2013

AIM:To investigate the weight loss and glycemic control status [blood glucose, hemoglobin A1c (HbA1c) hypoglycaemic treatment]. METHODS:The primary risk factor for type 2 diabetes is obesity, 90% of all patients with are overweight or obese.Although a remarkable effect bariatric surgery profound durable resolution clinical manifestations, little known about difference among various surgical procedures on remission.Data from referred during 3-year period (from January 2009 to December 2011)...

10.3748/wjg.v19.i39.6590 article EN cc-by-nc World Journal of Gastroenterology 2013-01-01

AIMTo report early imaging assessment of ablated area post electrochemotherapy (ECT) in patients with locally advanced pancreatic cancer (LAPC). METHODSECT was performed 19 LAPC enrolled an approved ongoing clinical phase Ⅰ/Ⅱ study.Before and after ECT, 18 underwent computed tomography (CT) scan, 11 morphological functional magnetic resonance (MR) scan (dynamic contrast enhanced-MRI) calculating wash-in slope (WIS) wash-out (WOS); diffusion weighted pseudo-diffusivity (Dp), perfusion...

10.3748/wjg.v23.i26.4767 article EN cc-by-nc World Journal of Gastroenterology 2017-01-01

Human pancreatic cancer is currently one of the deadliest cancers with high mortality rate. It has been previously shown that (-)-epigallocatechin-3-gallate (EGCG), most abundant catechin found in green tea, showed suppressive effects on human cells. Bleomycin, (BLM), an anti-cancer chemotherapeutic drug induces DNA damage, antitumor by induction apoptosis several cell lines and also The present study investigated for first time, inhibitory effect EGCG BLM growth.Using MIA PaCa-2 cells...

10.1186/s13027-015-0016-y article EN cc-by Infectious Agents and Cancer 2015-07-13

The treatment of ventral hernias is still a subject debate. affixing prosthesis and the subsequent introduction laparoscopic have reduced complications recurrences. high incidence seromas costs remain open problems. At our Department between January 2008 December 2011, 87 patients (43 over 65 years), out total 132, with defects wall whose major axis was less than 10 cm, or minor multiple (Swiss-cheese defect) on an not exceeding 12 cm underwent hernia repair (LVHR) primary transparietal...

10.1186/1471-2482-12-s1-s33 article EN cc-by BMC Surgery 2012-01-01

Aims: To test the efficacy of mini-gastric bypass (MGB) in treatment morbid obesity related to Prader–Willi Syndrome (PWS). Patients and Methods: Three young male patients (mean age 15.6 years) complaining with PWS were treated by MGB aim improve associated syndrome. Preoperative body mass index was 51 ± 4.13 kg/m2. Two suffered from both hypertension frequent sleep apnea crises. The mean preoperative level fasting plasma acyl ghrelin 1417.26 289.37 pg/ml. All underwent a laparoscopic MGB....

10.3109/08941939.2013.832824 article EN Journal of Investigative Surgery 2013-09-24

RFA is a safe and effective procedure for treating unresectable primary or secondary liver malignancies, but it not without complications. The most common reported complications include abdominal hemorrhage, bile leakage, biloma formation, hepatic abscesses, neoplastic seeding. aim of this study to evaluate the feasibility percutaneous use surgical sealant with new coaxial bilumen catheter, prevent perihepatic bleeding dissemination cancer cells through needle-electrode (neoplastic seeding)...

10.1186/s13027-015-0006-0 article EN cc-by Infectious Agents and Cancer 2015-04-09

Hepatocellular carcinoma (HCC) is one of the major cause for cancer in world. Aim this case-control study was to investigate distribution pattern HCV genotypes among HCC patients and suggest whether infection with specific subtypes may be associated an increased risk progression cancer. 152 anti-HCV positive patients, fulfilling criteria from Barcelona 2000 EASL conference, 568 chronically infected but without as control group were included study. Serum each patient evaluated viral load...

10.1186/s13027-017-0162-5 article EN cc-by Infectious Agents and Cancer 2017-10-06

Background: Eighty percent of patients with pancreatic adenocarcinoma present a locally advanced or metastatic disease at diagnosis and are not eligible for surgery if palliative intent. In cases (LAPC), the combination chemo radiotherapy is only therapeutic option correlates median survival 15 months (10 without treatment), partial remission in 50% cases. The feasibility safety Electrochemotherapy (ECT) have been demonstrated treatment deep tumors. Aim: aim study to evaluate efficacy...

10.3390/jcm10174011 article EN Journal of Clinical Medicine 2021-09-05

To report our cancer centre experience in the biliary tumours incidence other than cholangiocellular-carcinoma, emphasizing radiological features.197 patients with disease undergoing Gd-EOB-DTPA-enhanced MRI were reviewed. Four radiologists evaluated retrospectively size, structure, anatomical site and signal intensity of lesions on MRI. Enhancement-pattern during arterial-, portal- late-phase ultrasound, CT MR study was assessed as well enhancement pattern hepatobiliary-phase MRI.23...

10.1259/bjr.20160561 article EN British Journal of Radiology 2017-07-21

Plexiform fibromyxoma (PF), also referred to as plexiform angiomyxoid myofibroblast tumor, is an exceedingly rare mesenchymal neoplasm primarily affecting the stomach. Herein, we present a case of PF diagnosed in 71-year-old male with history lung cancer, initially suspected have gastrointestinal stromal tumor (GIST) stomach, who subsequently underwent subtotal gastrectomy. The histopathological and molecular features including mutations ABL1, CCND1, CSF1R, FGFR4, KDR, MALAT1-GLI1 fusion,...

10.3390/ijms25094847 article EN International Journal of Molecular Sciences 2024-04-29
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