- Cancer, Stress, Anesthesia, and Immune Response
- Tea Polyphenols and Effects
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Tannin, Tannase and Anticancer Activities
- Anesthesia and Sedative Agents
- Neuropeptides and Animal Physiology
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Pharmacological Effects of Natural Compounds
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cannabis and Cannabinoid Research
- Curcumin's Biomedical Applications
- Anesthesia and Pain Management
- MicroRNA in disease regulation
- Cancer Treatment and Pharmacology
- Cancer Research and Treatments
- Cancer Cells and Metastasis
- Nigella sativa pharmacological applications
- Hedgehog Signaling Pathway Studies
- Liver Disease Diagnosis and Treatment
- Cancer survivorship and care
- Nanoplatforms for cancer theranostics
- Retinoids in leukemia and cellular processes
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2015-2024
University of Milan
2022
Instituto de Histología y Embriología de Mendoza
2022
Consejo Nacional de Investigaciones Científicas y Técnicas
2022
Icesi University
2022
University of Padua
2022
Pain and Rehabilitation Medicine
2019
Istituti di Ricovero e Cura a Carattere Scientifico
2018
Pain Management Institute
2018
Creative Research Enterprises (United States)
2018
Breast cancer is considered the most common for women worldwide and it now second leading cause of cancer-related deaths among females in world. Since breast highly resistant to chemotherapy, alternative anticancer strategies have been developed. In particular, many studies demonstrated that curcumin, a derivative turmeric, can be used as natural agent treatment some types by playing antiproliferative antioxidant effects. our study, we assessed antitumor activities curcumin ER-negative human...
Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The best chemotherapeutic agent used to treat pancreatic gemcitabine. However, gemcitabine treatment associated with many side effects. Thus novel strategies involving less toxic agents for of are necessary. Curcumin one such that inhibits proliferation and angiogenesis wide variety tumor cells, through modulation cell signalling pathways. In this study, we investigated...
The metastatic process is the most serious cause of cancer death. Norepinephrine, secreted in chronic stress conditions, stimulates motility breast and colon cells through β-adrenergic receptor. On these bases, we examined its possible role metastasis formation development vitro vivo. Treatments with norepinephrine (β2-adrenoreceptor agonist) mice xenografted human DU145 prostate increased potential cells. Specifically, showed that treatment induced a significant increase migratory activity...
Morphine is considered a highly potent analgesic agent used to relieve suffering of patients with cancer. Several in vitro and vivo studies showed that morphine also modulates angiogenesis regulates tumour cell growth. Unfortunately, the results obtained by these are still contradictory. In order better dissect role cancer growth we performed on ER-negative human breast carcinoma cells, MDA.MB231 heterotopic mouse model triple negative cancer, TNBC. We demonstrated enhanced proliferation...
Purpose: Complementary and Alternative Medicine (CAM) interventions are widely used by patients with chronic disorders, including cancer, may interact cancer treatment. Physicians often unaware of this, probably due to poor patient-physician communication on CAM. The purpose this study was evaluate physicians' knowledge, attitudes practice patterns regarding CAM in a survey conducted Italy. Methods: A questionnaire administered 438 physicians (11 Italian hospitals) who predominantly treat...
Postoperative delirium, the onset of confusion/delirium during early postoperative phase, is most common complication in older adults and represents a medical emergency that requires immediate assessment treatment. On other hand, term cognitive decline or dysfunction refers to wide spectrum clinical conditions featuring variety neuropsychological domains including memory, executive functioning, speed processing emerging week months after anesthesia surgery. delirium represent two distinct...
Human pancreatic cancer is currently one of the deadliest cancers with high mortality rate. It has been previously shown that (-)-epigallocatechin-3-gallate (EGCG), most abundant catechin found in green tea, showed suppressive effects on human cells. Bleomycin, (BLM), an anti-cancer chemotherapeutic drug induces DNA damage, antitumor by induction apoptosis several cell lines and also The present study investigated for first time, inhibitory effect EGCG BLM growth.Using MIA PaCa-2 cells...
To explore the effect of breakthrough cancer pain (BTcP) treatment on quality sleep and other aspects health-related life (HRQoL) in patients with pain.
SARS-CoV-2 infection can impact the physical, cognitive, mental health of patients, especially in those recovered intensive care units. Moreover, it was proved that effects virus may persist for weeks or months. The term long-COVID post-COVID syndrome is commonly used indicating a variety physical and psychological symptoms continue after resolution acute phase. This narrative review aimed at providing an updated overview disorders COVID-19 survivors, by summarizing data already published...
Telemedicine, the remote delivery of healthcare services, represents a great opportunity for cancer pain management. A care model telemedicine that combines visits and hospital access could be an effective safe strategy management patients.A retrospective study was conducted using dataset program at Istituto Nazionale Tumori Naples, Italy assessing efficacy telehealth-based care. Demographic, clinical, process variables were investigated.A total 226 cases 489 included in analysis. The mean...