Helian Li

ORCID: 0000-0001-7701-6826
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About
Contact & Profiles
Research Areas
  • Single-cell and spatial transcriptomics
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Sepsis Diagnosis and Treatment
  • High Altitude and Hypoxia
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Tryptophan and brain disorders
  • Exercise and Physiological Responses

Fudan University
2025

Shanghai Public Health Clinical Center
2023-2024

We aimed to characterize the phenotype of neuromyelitis optica spectrum disorder (NMOSD) in presence and absence Sjogren's disease (SjD) develop a predictive nomogram evaluate risk coexisting SjD within single tertiary-center cohort NMOSD patients. Paraclinical clinical features patients with were compared between those without SjD. Zstats v1.0 was utilized randomly allocate participants into derivation group (108 patients) validation (47 at ratio 7:3. Logistic regression analysis used...

10.1186/s13075-025-03538-3 article EN cc-by-nc-nd Arthritis Research & Therapy 2025-04-05

Abstract Immunophenotyping is proving crucial to understanding the role of immune system in health and disease. High-throughput flow cytometry has been used extensively reveal changes cell composition function at single-cell level. Here, we describe six optimized 11-color panels for deep immunophenotyping human whole blood. A total 51 surface antibodies, which are readily available validated, were selected identify key populations evaluate their functional state a single assay. The gating...

10.1007/s43657-022-00092-9 article EN cc-by Phenomics 2023-02-23
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