Jennifer Adeghate

ORCID: 0000-0001-7713-3467
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Retinal and Macular Surgery
  • Retinal Development and Disorders
  • Ophthalmology and Visual Impairment Studies
  • Pesticide and Herbicide Environmental Studies
  • Pancreatic function and diabetes
  • Intraocular Surgery and Lenses
  • Diabetes Treatment and Management
  • Pesticide Exposure and Toxicity
  • Bacterial Identification and Susceptibility Testing
  • Enterobacteriaceae and Cronobacter Research
  • Ophthalmology and Visual Health Research
  • Cholinesterase and Neurodegenerative Diseases
  • Ocular Diseases and Behçet’s Syndrome
  • Mesenchymal stem cell research
  • Photoreceptor and optogenetics research
  • Patient Satisfaction in Healthcare
  • Ocular Infections and Treatments
  • Corneal surgery and disorders
  • Traumatic Ocular and Foreign Body Injuries
  • Diet and metabolism studies
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Columbia University
2018-2024

Manhattan Eye, Ear and Throat Hospital
2023-2024

Northwell Health
2023-2024

Insall Scott Kelly Institute
2024

University of Pittsburgh
2019-2024

Vitreous Retina Macula Consultants of New York
2024

UPMC Health System
2024

Semmelweis University
2016-2023

Columbia University Irving Medical Center
2023

University of Pittsburgh Medical Center
2020-2021

Purpose: To report novel variants in IFT140 and IFT172 genes three patients with similar retinal dystrophy phenotypes. Methods: This is a case series of two brothers known dystrophy, renal disease, skeletal changes who shared the same gene, an unrelated individual variant uncertain significance gene phenotype. Results: Two siblings (a 51-year-old male 46-year-old male) presented abnormalities, kidney disease were found to have along another, previously reported variant. An phenotype was...

10.1159/000545390 article EN cc-by-nc Case Reports in Ophthalmology 2025-03-26

Purpose: The purpose of this study was to assess factors affecting follow-up eye care in participants enrolled the Philadelphia Telemedicine Glaucoma Detection and Follow-up Study, such as awareness ocular diagnosis, availability transportation methods, reasons for missing appointments. Methods: sample included 172 who were randomized intervention group contacted by social worker. Results: A total 155 completed assessment form, which used an instrument adherence care. main exam appointments...

10.1080/00981389.2019.1614711 article EN Social Work in Health Care 2019-05-23

KEYWORDS: Type 2 Diabetes mellituscardiovascular diseasesrenal diseases, pharmacotherapyT2DM comorbiditieshypoglycemic agents

10.1080/13543784.2021.1865914 article EN Expert Opinion on Investigational Drugs 2020-12-17

Blindness from glaucoma can be prevented by early detection and treatment. Telemedicine improves access to treatment in high-risk populations that face barriers receiving adequate ophthalmic care. We used a practice-based telemedicine screening model at two health centers. imaging of the fundus optic nerve, followed complete eye exam same location for participants with abnormal findings, unreadable images, or ocular hypertension (OHTN), was performed. A total 182 were screened, whom 108...

10.1353/hpu.2018.0103 article EN Journal of Health Care for the Poor and Underserved 2018-01-01

The purpose of this study was to evaluate the effects a six-month social worker intervention for participants with glaucoma-related diagnosis in an urban ophthalmic setting (N = 40). assessed common barriers eye care, helping transportation, access low-vision resources, and supportive counseling. Distress Thermometer, Patient Health Questionnaire-9, satisfaction survey were administered determine effect participants' overall impressions worker. most barrier care emotional distress (77.5...

10.1093/hsw/hly038 article EN Health & Social Work 2018-12-07

The effects of early (5-day) onset diabetes mellitus (DM) on retina ultrastructure and cellular bioenergetics were examined. retinas streptozotocin-induced diabetic rats compared to those non-diabetic using light transmission electron microscopy. Tissue localization glucagon-like-peptide-1 (GLP-1), exendin-4 (EXE-4), catalase (CAT) in rat was conducted immunohistochemistry, while the retinal plasma concentration GLP-1, EXE-4, CAT measured with ELISA. Lipid profiles kidney liver function...

10.3390/cells10081981 article EN cc-by Cells 2021-08-04

Staphylococcus saprophyticus is a well-known urinary pathogen in acute cystitis young females. We completed retrospective overview of the distribution tract infections (UTIs) occurring 2014, at Semmelweis University hospitals and Heim Pál Children's Hospital. Six age-groups (ages 0-100) were examined, with frequency S. females being: 0.1% (0-4), 0.7%, (5-15), 7.4% (16-24), 1.2% (25-39), 0.4% (40-59) (60-100), being 3(rd) most common aged 16-24. In males, was only isolated from those 5-15....

10.1556/030.63.2016.1.4 article EN Acta Microbiologica et Immunologica Hungarica 2016-03-01

Background:Cataracts are a major cause of visual impairment and blindness in the United States worldwide.Introduction:Risk factors for cataracts include age over 40 years, smoking, diabetes, low socioeconomic status, female sex, steroid use, ocular trauma, genetic factors, exposure to ultraviolet-B light. Community-based telemedicine vision screenings can be an efficient method detecting underserved populations. The Philadelphia Telemedicine Glaucoma Detection Follow-Up Study reports...

10.1089/tmj.2019.0170 article EN Telemedicine Journal and e-Health 2019-11-13

Retinal membrane peeling requires delicate manipulation. The presence of the surgeon's physiological tremor, high variability and often low quality ophthalmic image, excessive forces make tasks more challenging. Preventing unintended movement caused by tremor unintentional can reduce injury. With use an actively stabilized handheld robot, we employ a monocular camera-based surface reconstruction method to estimate retinal plane propose virtual fixture with application hard stop motion...

10.1115/1.4051686 article EN Journal of Medical Devices 2021-07-07

Objectives . Premature neonates are susceptible to opportunistic and nosocomial infections. Efforts have been made determine whether the neonatal gut microbiome possesses potential for causing bloodstream infections in newborns via microbial translocation from gastrointestinal tract. We aimed examine similarities coagulase-negative staphylococci (CoNS) strains found tract bacteremic neonates. Methods CoNS isolated blood cultures perianal pharyngeal swab samples of two intensive care units...

10.1155/2020/3509676 article EN cc-by Canadian Journal of Infectious Diseases and Medical Microbiology 2020-07-21

Abstract Purpose: To describe chorioretinal changes in a single case of Boucher-Neuhauser Syndrome (BNHS) over 45 years follow-up. Methods: Retrospective chart review was performed. Color fundus photography from 1977 to 2003 obtained and digitized. Current with widefield imaging. High-resolution spectral-domain optical coherence tomography (OCT) Genetic analysis performed using an inherited retinal disorders panel. Results: Fundus examination demonstrated central atrophy sclerotic choroidal...

10.1097/icb.0000000000001556 article EN Retinal Cases & Brief Reports 2024-03-06

We hypothesize that the injection of JP4-039, a mitochondria-targeted nitroxide, prior to irradiation mouse retina may decrease apoptosis and reduce neutrophil macrophage migration into retina. In our study, we aimed examine effects JP4-039 in using fluorescent microscopy, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay, flow cytometry. Forty-five mice one eye per were used. Group 1, microscopy was used determine retinal uptake 10 µL (0.004 mg/µL) intravitreally...

10.3390/ijms25126515 article EN International Journal of Molecular Sciences 2024-06-13

Purpose: To report a case of secondary unilateral MEWDS following blunt trauma to the eye. Methods: Observational one patient. Results: A 25-year-old male initially presented after being hit in left eye with football, visual acuity 20/50, traumatic iritis, commotio retinae, vitreous hemorrhage, and large pigment epithelial detachment superior macula. He was lost follow-up for two years before presenting sudden decrease vision. On exam, best corrected VA (BCVA) counting fingers clinical exam...

10.1097/icb.0000000000001648 article EN Retinal Cases & Brief Reports 2024-08-02

Purpose: This article assesses anatomical and visual outcomes after intravitreal antivascular endothelial growth factor (anti-VEGF) treatment in fellow eyes with wet age-related macular degeneration (AMD). Methods: A retrospective chart review was conducted of 349 patients diagnosed AMD between 2005 2017 at a single academic institution. Initial diagnosis unilateral minimum follow-up time 1 year were required for inclusion. Individuals excluded if the initial made an outside institution,...

10.1177/2474126419865990 article EN Journal of VitreoRetinal Diseases 2019-09-06

Our aim was to find chlorine-substituted antidotes against organophosphate poisoning and compare their pharmacokinetics parent compound, K-203. White male Wistar rats were intramuscularly injected with K-203, K-867 or K-870. Serum, brain, kidneys, liver, lung, eyes, testes tissues taken after 5, 15, 30, 60, 120 min analyzed using reversed-phase high-performance liquid chromatography. K-867, K-870 present in every tissue that analyzed, including the serum, testes, lungs, brain. The serum...

10.3390/molecules25051250 article EN cc-by Molecules 2020-03-10

Vasoproliferative tumors (VPT) are benign retinal lesions that may cause epiretinal membrane proliferation and tractional detachments (TRD). We describe a case of 71-year-old woman who presented with macula involving TRD in the setting VPT. Given limited number publications on management these cases, we aim to articulate some principles believe be helpful planning surgical approach maximizes postoperative anatomic functional outcomes. hope our video provides useful guidance preparing...

10.3928/23258160-20230726-02 article EN Ophthalmic surgery, lasers & imaging retina 2023-08-01

To describe tele-retinal abnormality image findings from the Manhattan Vision Screening and Follow-up Study (NYC-SIGHT), which aims to investigate whether community-based eye health outreach strategies using telemedicine can improve visual outcomes among at-risk populations in Upper Manhattan.

10.1089/tmj.2023.0134 article EN Telemedicine Journal and e-Health 2023-08-31
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