- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Software Reliability and Analysis Research
- Reliability and Maintenance Optimization
- Risk and Safety Analysis
- Blood donation and transfusion practices
- Advanced Manufacturing and Logistics Optimization
- Healthcare Operations and Scheduling Optimization
- Optimization and Packing Problems
- Advanced Optimization Algorithms Research
- RFID technology advancements
- Facility Location and Emergency Management
- Supply Chain and Inventory Management
- Vehicle Routing Optimization Methods
- Optimization and Mathematical Programming
- Forecasting Techniques and Applications
- Optimization and Search Problems
- Quality and Supply Management
- Multi-Criteria Decision Making
- Advanced Statistical Process Monitoring
- Experimental Learning in Engineering
- Scheduling and Optimization Algorithms
- Energy and Environment Impacts
- Formal Methods in Verification
- Optimization and Variational Analysis
University of Pittsburgh
2015-2024
World Health Organization
2011
University of Iowa
1983
:Lean manufacturing has traditionally been thought of as being applicable mostly to the discrete industries since process sector lends itself less naturally many lean techniques. There is, however, considerable interest in extending because its dramatic results sector. We argue that different techniques can be applied varying degrees depending on specific characteristics environment. In this article we develop a general classification scheme for industry, which managers companies use order...
New vaccine introductions have put strains on supply chains around the world. While increasing storage and transportation may be most straightforward options, it is also important to consider what financial operational benefits can incurred. In 2012, suboptimal coverage impending prompted Republic of Benin's Ministry Health (MOH) explore ways improve their chain.Working alongside Beninese MOH, we utilized our computational model, HERMES, impact cost availability three possible options: (1)...
Many countries, such as Niger, are considering changing their vaccine vial size presentation and may want to evaluate the subsequent impact on supply chains, series of steps required get vaccines from manufacturers patients. The measles is particularly important in a country prone outbreaks.We developed detailed discrete event simulation model chain representing every vaccine, storage location, refrigerator, freezer, transport device (e.g., cold trucks, 4 × carriers) Niger Expanded Programme...
In many developing countries, inefficiencies in the supply chain for World Health Organization's Expanded Program on Immunization (EPI) vaccines are of grave concern; these result thousands people not being fully immunized and creates significant risk disease epidemics. Thus, there is a great deal interest countries building tools to analyze optimize how flow down several levels from manufacturers vaccine recipients. This article develops mathematical model typical distribution networks...
Abstract In most low‐ and middle‐income countries supported by the World Health Organization's Expanded Program on Immunization, vaccines are distributed through a legacy medical supply chain that is typically not cost‐efficient. Vaccines require storage transport in temperature‐controlled environment; this requires “cold” distribution with capacity constraints cold transport. We propose an approach to redesigning vaccine includes locating set of intermediate centers (DCs) determining flow...
Abstract We describe a simple modification of Palmer's heuristic for scheduling jobs in flow shop. While the additional computation required is relatively small, performance algorithm compares very well with that more sophisticated and better Campbell, et al. (1970) at fraction effort by latter.
Abstract Radio Frequency Data Communications (RFDC)technology is rapidly becoming a critical component of many traditional industrial engineering functions including materials tracking, inventory control, warehousing, order processing, shipping and database management. As means moving information, RFDC has attractive features, such as speed, accuracy, reliability, convenience low operating costs. When implementing systems major problem to quickly efficiently determine the locations where...
Background When addressing the urgent task of improving vaccine supply chains, especially to accommodate introduction new vaccines, there is often a heavy emphasis on stationary storage. Currently, donations chains occur largely in form storage equipment. Methods This study utilized HERMES-generated detailed, dynamic, discrete event simulation model Niger chain compare impacts availability adding cold versus transport capacity at different levels and determine whether alone would be enough...
Many of the world's vaccine supply chains do not adequately provide vaccines, prompting several questions: how are currently structured, these structures closely tailored to individual countries, and should be radically redesigned?We segmented 57 GAVI-eligible countries' based on their structure/morphology, analyzed whether segments correlated with differences in country characteristics, then utilized HERMES develop a detailed simulation model three sample explore cost impact various...
We investigated whether introducing the rotavirus and pneumococcal vaccines, which are greatly needed in West Africa, would overwhelm existing supply chains (i.e., series of steps required to get a vaccine from manufacturers target population) Niger.As part Bill Melinda Gates Foundation-funded Vaccine Modeling Initiative, we developed computational model determine impact these new vaccines Niger's Expanded Program on Immunization chain.Introducing either or 7-valent conjugate could available...
Although the substantial burdens of rotavirus and pneumococcal disease have motivated many countries to consider introducing vaccine (RV) heptavalent conjugate (PCV-7) their National Immunization Programs (EPIs), these new vaccines could affect countries' supply chains (i.e., series steps required get a from manufacturers patients). We developed detailed computational models Trang Province, Thailand, chain simulate various RV PCV-7 presentations combinations. Our results showed that volumes...
The Expanded Programme on Immunization (EPI) was established in 1974 to ensure that children all around the world benefit from life-saving vaccines. However, many low and middle income countries, it is extremely difficult vaccinate entire population with standard regimen of One important reason for this geographically dispersed or nomadic populations. To improve vaccination rates, these countries typically use outreach, where health workers take vaccines remote locations. Outreach last,...
A critical factor in the adoption of Radio Frequency Identification (RFID) technology is level read accuracy that achieved. With passive tags, depends on volume region receives sufficient power from reader. Most current research considers powering a reader to be determined only by its range (i.e. distance). However, also relative orientations and tag antennas their polarisations. In particular, when positions are not fixed, locations tags can have significant effect success interrogation...
This paper addresses the optimal allocation of reliability among components that are to be assembled into a system. While it is generally accepted notion component's cost an increasing function its reliability, most research date adopts exponentially increasing, closed-form functions relate and reliability. However, in practice such often unknown or difficult construct, more reasonable describe cost-reliability relationships via discrete data sets. We consider situations, where each...