- Statistical Methods and Bayesian Inference
- Mesenchymal stem cell research
- Nutrition and Health in Aging
- Hematopoietic Stem Cell Transplantation
- Vitamin D Research Studies
- Respiratory viral infections research
- Temporomandibular Joint Disorders
- Body Composition Measurement Techniques
- Bone health and osteoporosis research
- Influenza Virus Research Studies
- Oral health in cancer treatment
- Advanced Statistical Methods and Models
- Cancer Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Statistical Distribution Estimation and Applications
- COVID-19 Clinical Research Studies
- Research on Leishmaniasis Studies
- Dysphagia Assessment and Management
- COVID-19 and Mental Health
- Bacterial Infections and Vaccines
- COVID-19 epidemiological studies
- Renal Transplantation Outcomes and Treatments
- Bayesian Methods and Mixture Models
- Toxoplasma gondii Research Studies
- Long-Term Effects of COVID-19
Universidade Federal do Paraná
2015-2024
Hospital de Clínicas Universidade Federal do Paraná
2015-2024
Diabetics are at increased risk for impaired mobility and strength, frequently related to the disease control. Sarcopenia is reduction of muscle mass associated with decrease in strength and/or performance, resulting worse morbidity chronic diseases.The objectives this paper was assess prevalence sarcopenia patients type 2 diabetes mellitus (T2DM) determine its association characteristics, progression, complications, as well changes bone mineral density. The sample consisted T2DM followed...
COVID-19 is a multisystem disease that presents acute and persistent symptoms, the postacute sequelae (PASC). Long-term symptoms may be due to consequences from organ or tissue injury caused by SARS-CoV-2, associated clotting inflammatory processes during COVID-19. Various strategies are being chosen clinicians prevent severe cases of COVID-19; however, single treatment would not efficient in treating such complex disease. Mesenchymal stromal cells (MSCs) known for their immunomodulatory...
RESUMO Realizou-se estudo transversal do sofrimento mental com 1.021 professores ensino público Paraná. Utilizou-se o Self-Report Questionnaire para distúrbios psíquicos menores, os inventários de ansiedade e depressão Beck, questionário sociodemográfico morbidade autorreferida. Os testes Qui-quadrado, Exato Fisher Kruskal-Wallis foram utilizados na análise dos dados obtidos. Foram encontrados menores em 75%, 44% 70% das pessoas observadas no presente estudo, havendo associação significativa...
Background: The coronavirus disease pandemic has deeply impacted various societal sectors, altering the distribution patterns of community respiratory viruses. As children and teenagers are commonly affected by these viruses, monitoring infections within groups can provide insights into viral dynamics during periods with without containment measures. Methods: This study used data from an ongoing active epidemiological surveillance program that included hospitalized acute illnesses Curitiba,...
Background. The aim of this study was to compare the prevalence low muscle mass and sarcopenia in patients with type 2 diabetes mellitus (T2DM) versus paired controls (control group, CG) association between chronic complications. Methods. Men women ≥50 years T2DM (T2DM T2DMG) were recruited during routine outpatient visits. Total body densitometry handgrip strength (HGS) evaluated T2DMG CG, while also for physical performance using gait speed (GS) test. Sarcopenia diagnosed according...
Bruxism is defined as a repetitive activity of masticatory muscles, characterized by the clenching or grinding teeth, which can occur during wakefulness (awake bruxism) sleep (sleep bruxism).The objectives present study were to determine prevalence awake bruxism and its associated factors.Sample was composed 50 participants both genders, aged between 18 60 years, submitted clinical examination - observe presence tooth wear, marks on mucosa, masseter muscles hypertrophy self-applied...
Graft failure (GF) is one of the major concerns after allogeneic hematopoietic cell transplantation (allo-HCT) and remains a significant cause morbidity mortality. Although previous reports have associated presence donor-specific HLA antibodies (DSAs) with an increased risk GF unrelated donor allo-HCT, recent studies failed to confirm this association. We sought validate DSAs as factor for hematologic recovery in allo-HCT setting. retrospectively evaluated 303 consecutive patients who...
The fear of childbirth (FOC) harms maternal and fetal health, however it has been little studied in Brazil. This research aimed to determine the prevalence FOC a maternity hospital southern Brazil identify its associated factors.The Wijma Delivery Expectancy Questionnaire - W-DEQ(A) was used assess FOC, relationship with sociodemographic variables, gestational history, aspects current pregnancy, knowledge about childbirth, anxiety symptoms (Beck Anxiety Inventory), depressive (Edinburgh...
Purpose: Sepsis is a condition with high mortality rates and its diagnosis remains challenge. We assessed epidemiological, clinical data, multiple biomarker profiles, blood culture respect to sepsis predictors of outcome. Methods: In total, 183 patients who were suspected having underwent collection followed up for 7 days. Sepsis-related Organ Failure Assessment (SOFA) Acute Physiology Chronic Health Evaluation (APACHE) II scores calculated daily; biomarkers test results evaluated. Results:...
Determine food intake and levels of serum magnesium (Mg) calcium (Ca) correlate these minerals with pain, quality life depression risk in women without fibromyalgia (FM).Fifty-three diagnosed FM 50 healthy participated the study, where all them had equivalent age body mass index (BMI). All underwent anthropometric assessment, physical exams pain perception threshold tender point (TP) count, blood sample collection, filling out impact questionnaire (FIQ), Patient Health Questionnaire-9...
Objective To evaluate the relationship between dysphagia and sarcopenia in patients with head neck cancer (HNC). Methods A cross-sectional, prospective study, sample by convenience, including men HNC during their initial oncologic evaluation. Patients answered questionnaires (demographic data, lifestyle habits, disease characteristics Short International Physical Activity Questionnaire). Swallowing capacity, bioelectrical impedance (BIA), handgrip strength (HGS) physical performance test...
To evaluate the prevalence of osteosarcopenia and association with trabecular bone score (TBS) in a group patients type 2 diabetes mellitus(T2DMG) compared paired control (CG).Cross-sectional study men women ≥ 50 years recruited by convenience. Patients both groups answered questionnaires underwent evaluation mineral density (BMD), handgrip strength (HGS), TBS. The T2DMG also gait speed (GS) test. Sarcopenia was defined as low lean mass plus HGS or GS according to Foundation for National...
Abstract Objective Correlate serum magnesium (Mg) and Calcium (Ca) levels with body composition metabolic parameters in women fibromyalgia (FM). Patients methods Cross-sectional study compared a control group paired by age mass index (BMI) of adult diagnosed fibromyalgia. All participants went through assessment their dual-energy X-ray absorptiometry (DXA) had blood samples collected for dosing Mg, Ca, C-reactive Protein (CRP), lipidogram glycemia. Results: 53 FM (average 48.1 ± 8.2 years,...
Summary Cryptococcal meningitis is mainly caused by members of the C. neoformans/C. gattii species complexes. The ecological niches Cryptococcus have extensively been studied, but its epidemiological relationship with cases still unknown. In this study, we estimate between cryptococcal and tree pigeon populations, classical neoformans / sensu lato . We analysed records every patient whose cerebrospinal fluid culture yielded spp. during last 30 years at Clinical Hospital Curitiba. Data about...
In this paper, we further extend the recently proposed Poisson-Tweedie regression models to include a linear predictor for dispersion as well expectation of count response variable. The family considered is specified using only second-moments assumptions, where variance has form μ+ϕμp $\mu + \phi \mu^p$, µ expectation, ϕ and p are power parameters, respectively. Parameter estimations carried out an estimating function approach obtained by combining quasi-score Pearson functions. performance...
Abstract Background Respiratory infections are one of the leading causes mortality, and comorbid conditions play a significant role in severity fatality these infections. Aims We evaluated Charlson Comorbidity Index (CCI) score possible predictors mortality hospitalised patients with severe acute respiratory infection (SARI), aiming to test if CCI is valid in‐hospital prognostic indicator. Methods Patients older than 14 years, from 2010 2016 due SARI by viral who were submitted virus testing...
Abstract This study evaluated the seroprevalence of Toxoplasma gondii, Neospora caninum and Leptospira spp. in dogs from Foz do Iguaçu, Paraná, Brazil. Indirect immunofluorescent antibody test was used to detect antibodies anti-T.gondii anti-N. caninum. Immunoenzymatic assay microscopic serum agglutination were for screening anti-Leptospira spp., respectively. The results were: 67.02% samples reactive T.gondii 1.38% N. caninum, both without statistically significant variables. For indicated...
Donor-specific HLA antibodies (DSAs) have been recognized as a major risk factor for graft failure (GF) in adult patients with malignancies undergoing haploidentical transplantation post-transplantation cyclophosphamide (haplo-PTCy). However, the impact of DSAs after pediatric haplo-PTCy nonmalignant disorders (NMDs) has poorly reported. We sought to investigate whether preexisting adversely affect outcomes. retrospectively analyzed 59 (≤21 years) who received their first NMDs from January...
Resumo Fundamento O treinamento intervalado de alta intensidade (HIIT) tem sido sugerido como alternativa ao contínuo (TC) em indivíduos com diabetes mellitus (DM) devido à sua curta duração e potencial para melhorar a adesão exercício. No entanto, dados sobre seu impacto variabilidade da frequência cardíaca (VFC) são escassos. Objetivos Avaliar comparar os efeitos do HIIT TC capacidade no exercício, VFC corações isolados ratos diabéticos. Métodos Animais diabéticos (estreptozotocina...
ABSTRACT BACKGROUND: Treatment for inflammatory bowel disease (IBD) includes a variety of immunosuppressants and biological agents, which increase the risk infections due to altered cellular humoral immunity. Prevention these can be done through vaccination, however, patients with IBD are usually under-immunized. OBJECTIVE: Analyze immunization status confront it current recommendations verify if guidelines being followed correctly. METHODS: Analytical cross-sectional study including 239...
Objective To describe the clinical and epidemiological features of patients with without sepsis at critical care units a public hospital. Methods A cross-sectional study was carried out from May 2012 to April 2013. Clinical laboratory data in intensive were reviewed medical records. Results We evaluated 466 patients, 58% men, median age 40 years, 146 (31%) them diagnosed sepsis. The overall [...]
We propose a flexible class of regression models for continuous bounded data based on second-moment assumptions. The mean structure is modelled by means link function and linear predictor, while the variance relationship has form [Formula: see text], where text] are mean, dispersion power parameters respectively. fitted using an estimating approach quasi-score Pearson functions employed estimation quasi-beta model can automatically adapt to underlying distribution parameter. Furthermore,...