- Advanced Chemical Sensor Technologies
- Electrochemical Analysis and Applications
- Advanced biosensing and bioanalysis techniques
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Electrochemical sensors and biosensors
- Mental Health Research Topics
- Astro and Planetary Science
- Analytical Chemistry and Sensors
- Digital Mental Health Interventions
- Gas Sensing Nanomaterials and Sensors
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Chemical Analysis and Environmental Impact
- Neurogenetic and Muscular Disorders Research
- Bone Tissue Engineering Materials
- Radio Wave Propagation Studies
- Bone health and osteoporosis research
- Bone health and treatments
- Bone fractures and treatments
- Photoreceptor and optogenetics research
- Connective tissue disorders research
- Heterotopic Ossification and Related Conditions
- RFID technology advancements
- Emotion and Mood Recognition
Google (United States)
2024
Ames Research Center
2018-2021
The University of Sydney
2015-2019
Universities Space Research Association
2017
Objectives: To examine periprosthetic bone remodeling among the recipients of 2 types lower-limb osseointegrated systems, Integral Leg Prosthesis (ILP) and Osseointegration Prosthetic Limb (OPL) type A, over a >24-month period. Design: Retrospective cohort study. Setting: Private hospital, with specialized osseointegration unit. Patients: Twenty-eight patients transfemoral amputations were fitted systems. Of these patients, 15 received ILP 13 OPL implant. Intervention: Radiographic...
Hydroxyapatite (HA) is a widely studied biomaterial for its similar chemical composition to bone and osteoconductive properties. The crystal structure of HA flexible, allowing wide range substitutions which can alter bioactivity, biodegradation, mechanical properties the substituted apatite. thermal stability apatite an indication biodegradation in vivo. In this study, we investigated manganese-substituted hydroxyapatite (MnHA) as it reported that manganese enhance cell attachment compared...
Mobility outcomes and changes in bone mineral density (BMD) of the spine femoral necks response to unilateral osseointegrated implants was investigated over a 3-year period. A total 48 amputees who received an implant, comprising 33 trans-femoral (TFA) 15 trans-tibial (TTA), underwent dual-energy X-ray absorptiometry (DXA) scans lumbar (L2-L4) at baseline, 1-, 3-years follow-ups. outcomes, including Six-Minute-Walk Test (6MWT) Timed-Up-and-Go (TUG), were measured before surgery, 1 year, more...
ABSTRACT Electrodermal activity (EDA) is a physiological measure that used to index sympathetic arousal in response stressors and other perturbations. However, EDA underutilized real-world, population-level research clinical practice because of paucity remote measurement capabilities on commodity devices. The current study examined the continuous at scale quantify changes context diurnal circadian rhythms, demographic differences, high contexts such as public holidays moments (e.g., Super...
Abstract All forms of terrestrial life include cellular machinery to transform and regulate chemical energy flow through electron‐transfer pathways reliant upon key classes biological redox molecules; that evolved elsewhere, presumably, would possess a similar possibly overlapping set energy‐management molecules. A second universal processes in biology encompasses enzymatic change add or remove functional groups, such as phosphate moieties, biomolecules for variety purposes, from managing...
Electrodes have emerged as powerful tools for sensing various physiological signals, paving the way a new era of wearable consumer devices that offer in situ measurement and analysis. Electrodermal activity (EDA) sensors are used evaluating autonomic nervous system activity, wherein changes EDA associated with excitation reflecting stress, arousal, emotional changes. The Fitbit Sense 2 Pixel Watch two commercial passively measure using wrist-facing electrodes powering stress management...
Abstract Electrodermal activity (EDA) is a measure of sympathetic arousal that has been linked to depression in laboratory experiments. However, the inability EDA passively over time and real-world limited conclusions can be drawn about as an indicator mental health status outside controlled settings. Recent smartwatches have begun incorporate wrist-worn continuous sensors enable longitudinal measurement every-day life. This work (N=237, 4-week observation period) examines association...
Biological redox is a promising indicator of life for NASA’s future exploration missions Ocean Worlds. Electrochemical sensors are valuable tools detecting these biological signatures on Earth; however their application to planetary has been limited. All forms Earth contain cellular machinery that can transform and regulate chemical energy through electron transfer pathways performed by key classes naturally-occurring molecules including flavins, nicotinamides, porphyrins, quinones. In this...
Electrochemistry offers a wide range of analytical sensing capability and is therefore suited to serve variety NASA missions. Advancements in miniaturization automation addition inherent high sensitivity specificity have made electrochemical sensors especially attractive. Here, we present recent developments for use planetary exploration human This article highlights research the area as presented at Space symposium 236th ECS Meeting on October 16, 2019 Atlanta, GA.
A 3D-printed microfluidic device coupled with a fluidic processing system was developed to enable autonomous end-to-end sample handling and electrochemical characterization of an Ocean World analogue solution – synthetic seawater (SW). This dual-channel cell populated 14 electrodes performed measurements similar those used in the MECA Wet Chemistry Laboratory on board NASA’s Phoenix Lander that landed Mars 2008. Biological metallic redox events were evaluated using cyclic voltammetry Au, Pt,...
Electrochemical sensor devices are of interest in planetary exploration missions where detection life is a goal. All forms on Earth contain cellular machinery that can transform and regulate chemical energy through metabolic pathways. These processes oxidation-reduction reactions performed by four key classes molecules: flavins, nicotinamides, porphyrins, quinones (Crawford, 2001). redox may prove valuable technique for identifying differentiating these biomolecules become useful tool future...
<h3>Background</h3> The use of dual-energy X-ray absorptiometry (DXA) is a standard clinical procedure for the evaluation bone mineral density (BMD). Amputee patients are known to have decreased BMD and an increased risk osteoporosis in affected proximal femur hip region. major cause these issues absence adequate loading leading resorption accordance Wolff's law. <h3>Objectives</h3> In this paper, we present prospective study reporting changes among amputees who received osseointegrated...
2018 marks the 10-year anniversary of landing NASA Phoenix spacecraft on ice-rich northern plains Mars. The Lander carried Wet Chemistry Laboratory (WCL), a component instrument Microscopy, Electrochemistry, and Conductivity Analyzer (MECA) was used to perform comprehensive electrochemical characterization martian soil in an aqueous solution. Designed characterize habitability surface, WCL contained array ion selective electrodes, conductivity cell, platinum electrode measure redox...
The Cover Feature illustrates the use of a representative set life-critical redox molecules in synthetic seawater (SW) using electrochemical techniques. A well-developed assay indicates presence phosphatase(s) by comparing signatures substrate for, and product of, enzymatic process. Measured limits detection SW as low 10 nM are reported for naturally occurring 3.1 aM alkaline phosphatase over 60 min period, demonstrating promise sensitivity sensors effective life-detection tools future ocean...
A 3D-printed microfluidic device coupled with a fluidic processing system was developed to enable autonomous end-to-end sample handling and electrochemical characterization of an ocean world analogue solution – synthetic seawater (SW). This dual-channel cell populated 14 electrodes performed measurements similar those used in the MECA Wet Chemistry Laboratory on board NASA’s Phoenix Lander that landed Mars 2008. Biological metallic redox events were evaluated using cyclic voltammetry Au, Pt,...