A5079769178- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Connexins and lens biology
- Ion channel regulation and function
- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Botulinum Toxin and Related Neurological Disorders
- Musculoskeletal pain and rehabilitation
- Veterinary Pharmacology and Anesthesia
- Chemical Synthesis and Analysis
- Electrocatalysts for Energy Conversion
- Transcranial Magnetic Stimulation Studies
- Receptor Mechanisms and Signaling
- Neurotransmitter Receptor Influence on Behavior
- Sleep and Wakefulness Research
- Cannabis and Cannabinoid Research
- Nicotinic Acetylcholine Receptors Study
- Animal Behavior and Welfare Studies
- Enzyme Production and Characterization
- Neuropeptides and Animal Physiology
- Anesthesia and Pain Management
- Aldose Reductase and Taurine
- Asymmetric Synthesis and Catalysis
- Anesthesia and Sedative Agents
- Marine and coastal ecosystems
University of Nottingham
2009-2025
Florida College
2024
University of Florida
2024
Texas A&M University
1972-2020
Versus Arthritis
2018-2019
University of Manchester
2017
University of Minnesota
1965-2015
Amway (United States)
2006
Eli Lilly (United Kingdom)
1992-2005
Loughborough University
1992-2004
1. There seem to be two distinct methods of destruction the foot, once pain sensibility has been lost: first is a slow erosion and shortening associated with perforating ulcers under distal weight-bearing end foot. The second proximal disintegration tarsus in which mechanical forces often determine onset progress condition. 2. Once begins disintegrate it difficult halt rapid 3. It possible detect early stages this condition time take preventive measures. Routine palpation anaesthetic feet...
The objective of this study was to identify the risk factors associated with 3 presentations hock lesions (hair loss, ulceration, and swelling) in freestall-housed lactating cattle. By independent identification scoring of, analysis with, hair swelling, aim whether were common all 3, or differed among presentations. A cross-sectional conducted on 76 herds UK during winter housing period 2007 2008, a total 3,691 cows examined for lesions. randomly selected sample approximately 50 each herd...
Introduction Diffuse noxious inhibitory controls (DNIC) may be impaired in human subjects with osteoarthritis (OA) pain. Spontaneously occurring OA dogs is considered a valuable model of OA; however, methodology for assessing DNIC has not been fully developed. The aim this study was to develop suitable protocol using ice water immersion, similar protocols used humans. Objective This objective create an experimental inducing sedated or anesthetized dogs, ensuring it face validity future...
Meprins are zinc-endopeptidases of the astacin family, which expressed as membrane-bound or secreted forms in renal and intestinal brush-border membranes mouse, rat man. There two types meprin subunits, α β, form disulfide-bonded homo- heterodimers; further oligomerization is mediated by non-covalent interactions. Both subunits translated proenzymes that have to be activated removal an N-terminal propeptide. In gut, most probable activator trypsin. addition, plasmin has been shown activate...
Abstract The analgesic potential of cannabinoid (CB) receptor agonists is clinical interest. Improved understanding the mechanisms action cannabinoids at sites involved in modulation acute and sustained inflammatory nociceptive transmission, such as spinal cord, essential. In vivo electrophysiology was used to compare effect synthetic CB agonist, HU210, on transcutaneous electrical‐evoked responses dorsal horn neurons noninflamed anaesthetized rats with a peripheral carrageenin inflammation....
Reduced graphene oxide/aramid nanofiber (rGO/ANF) supercapacitor electrodes have a good combination of energy storage and mechanical properties, but ion transport remains an issue toward achieving higher densities at high current because the tightly packed electrode structure. Herein, carbon nanotubes (CNTs) are introduced to prevent rGO flake stacking improve rate capability rGO/ANF structural supercapacitor. The effect CNTs on composite electrode's electrochemical properties is...
The role of group I metabotropic glutamate (mGlu) receptors in neurodegeneration is controversial because the contradictory effects mGlu1/5 agonists vitro models neuronal cell death. In this study, novel and selective antagonists mGlu1 mGlu5: LY367385 LY367366 were found to show consistent neuroprotective against N-methyl-D-aspartate (NMDA)-induced excitotoxicity vivo. Furthermore, intraventricular administration reduced hippocampal death gerbils subjected transient global ischemia. Previous...
The present paper extends the work published in an earlier account by Harris & Wolfe (1955). Vertical migration of Daphnia magna Straus was there shown to be controlled two independent mechanisms, a photokinetic one responsible for ‘dawn rise’ and phototactic which linked orientation response. It is that whose eyes have been removed exhibit response, including inhibition movement at high light intensities, but no Consequently such animals can carry out vertical determined solely...