- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Sports injuries and prevention
- Orthopedic Surgery and Rehabilitation
- Total Knee Arthroplasty Outcomes
- Nerve Injury and Rehabilitation
- Knee injuries and reconstruction techniques
- Foot and Ankle Surgery
- Trauma Management and Diagnosis
- Lower Extremity Biomechanics and Pathologies
- Orthopedic Infections and Treatments
- Tendon Structure and Treatment
- Bone fractures and treatments
- Hip disorders and treatments
- Viral Infections and Outbreaks Research
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Ion channel regulation and function
- Protein Degradation and Inhibitors
- Ear Surgery and Otitis Media
- Nursing Diagnosis and Documentation
- Trauma and Emergency Care Studies
- Tracheal and airway disorders
- HIV Research and Treatment
- Electronic Health Records Systems
Loma Linda University
2021-2024
Mapúa University
2022-2023
University of North Carolina at Chapel Hill
2022
University of Miami
2016-2022
University of Utah Hospital
2022
Oregon Health & Science University
2018-2021
Steadman Philippon Research Institute
2017-2019
The Ohio State University
2019
Steadman Clinic
2018-2019
Southeastern Oklahoma State University
2018
Glioblastoma Multiforme (GBM) is the most common and lethal form of primary brain tumor in adults. Following standard treatment surgery, radiation chemotherapy, patients are expected to survive 12-14 months. Theorized cause disease recurrence these cell repopulation through proliferation treatment-resistant cancer stem cells. Current research has revealed curcumin, principal ingredient turmeric, can modulate multiple signaling pathways important for self-renewal survival.Following resection,...
Background: Patients with recurrent anterior glenohumeral instability after a failed Latarjet procedure remain challenge to address. Complications related this include large amounts of bone loss, resorption, and issues retained hardware that necessitate the need for revision surgery. Purpose: To determine outcomes patients who underwent surgery shoulder fresh distal tibial allograft. Study Design: Case series; Level evidence, 4. Methods: All consecutive allograft were prospectively enrolled....
American football is a leading cause of sports-related injuries, with the knee, ankle, and shoulder most commonly involved.The purpose this study was to describe epidemiology, characteristics, imaging findings ankle injuries in players at National Football League (NFL) Combine determine relationship player position. We hypothesized that there would be high relative incidence these compared other sports direct correlation between position.Cross-sectional study; Level evidence, 3.A...
Latency reversal strategies for HIV cure using inhibitor of apoptosis protein (IAP) antagonists (IAPi) induce unprecedented levels latent reservoir expression without immunotoxicity during suppressive antiretroviral therapy (ART). However, full targeting the may require combinatorial approaches. A Jurkat latency model screen IAPi combination partners demonstrated synergistic with bromodomain (BD) and extraterminal domain inhibitors (BETi). Mechanistic investigations CRISPR-CAS9 single-cell...
Potassium transport has frequently been assessed by measurement of <sup>86</sup>Rb. However, recent reports indicated that the K ion channels are selective to over Rb. Therefore, purpose this study was evaluate whether basal and stimulated fluxes Rb were equivalent in rat aorta absence endothelium. The ouabain-sensitive (active) uptake <sup>86</sup>Rb <sup>42</sup>K similar. efflux only 80% efflux. Norepinephrine KCl depolarization effluxes via a...
Patellar tendon ruptures may be considerably limiting, especially in younger and highly active patients. These injuries ultimately result a complete inability to maintain extension of the knee, thereby placing strict impediment on physical activity. As result, durable repair construct via surgery is necessary allow patients return their preinjury activity level. Because inherent difficulty maintaining patellar position after repair, avoid failure healing patella, we recommend using an...
Labral tears confirmed by magnetic resonance imaging (MRI) are a relatively common injury among collegiate athletes and can influence player's ability to compete at the professional level.To determine prevalence of MRI-confirmed shoulder labral injuries in football players entering National Football League (NFL) Combine further describe these tear location, player position, history surgical intervention, associated concomitant injuries.Descriptive epidemiology study.Data from 2009 2015 were...
Articular cartilage injuries of the knee are common among young, active patients presenting with pain, swelling, and/or mechanical symptoms. These have limited healing potential due to avascular nature hyaline cartilage. While several treatment options exist, osteochondral allograft (OCA) transplantation for has been used successfully in primary management large chondral or defects and salvage previously failed repair. OCA potentially yields a natural, matching contour native recipient...
In the treatment of recurrent anterior glenohumeral instability, Latarjet procedure has been shown to fail. This results in a need for viable revisional procedures patients who present with this challenging pathology. We report our preferred technique anatomical glenoid reconstruction using fresh osteochondral distal tibia allograft after failed procedure. bony augmentation employs readily available dense, weight-bearing osseous tissue source that excellent conformity, as well added benefit...
Background In a time-constrained clinical environment, physicians cannot feasibly document all aspects of an office visit in the electronic health record (EHR). This is especially true for patients with multiple chronic conditions requiring complex reasoning. It unclear how prioritize documentation information EHR. Objective The goal this study to examine tradeoffs made by when caring comparing content conversations resulting EHR documentation. Methods We used grounded theory method...
The medial collateral ligament (MCL) is one of the most commonly injured structures in knee, especially young athletes. impact MCL injury on National Football League (NFL) performance elite collegiate athletes has not yet been described literature.We aim to (1) describe prevalence and severity injuries NFL Combine participants, (2) detail management, (3) analyze terms draft position, games played, started, snap percentage.Cohort study; Level evidence, 3.A retrospective review all...
Massive, irreparable rotator cuff tears are challenging to treat and associated with pain severe limitation in shoulder elevation due the proximal migration of humeral head and, consequently, subacromial impingement. Furthermore, retraction tendons combination fat infiltration muscular weakness results unpredictable treatment outcomes. While conservative may be warranted for low-demand patients, surgical is often indicated a successful return activities daily living as well an improved...
Injuries to the acromioclavicular (AC) joint are common, particularly in young and active population. Approximately 9% of all shoulder girdle injuries involve AC joint, dislocations represent approximately 8% throughout body. graded as type I through VI according Rockwood classification. Type II typically treated nonoperatively, whereas IV, V, most often surgically. A variety surgical techniques have been described, including anatomic nonanatomic reconstruction. However, up 80% patients go...
Salmonella osteomyelitis is uncommon in healthy patients. Because of its slow, indolent course and often remote presentation, diagnosis may be difficult. A case the tibia secondary to enteritidis was diagnosed after a biopsy for presumed fibrous dysplasia performed.