- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Energy and Environment Impacts
- Climate Change and Health Impacts
- Vehicle emissions and performance
- Noise Effects and Management
- Atmospheric chemistry and aerosols
- Urban Transport and Accessibility
- Health disparities and outcomes
- Recycling and Waste Management Techniques
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Birth, Development, and Health
- Urban Green Space and Health
- Traffic and Road Safety
- Toxic Organic Pollutants Impact
- Hedgehog Signaling Pathway Studies
- Indoor Air Quality and Microbial Exposure
- Environmental and Social Impact Assessments
- Carcinogens and Genotoxicity Assessment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Global Public Health Policies and Epidemiology
- Municipal Solid Waste Management
- Environmental Justice and Health Disparities
- Data-Driven Disease Surveillance
University of Chile
2014-2023
Instituto de Salud Pública de Chile
2016-2023
University of Castilla-La Mancha
2018
Centro Agronomico Tropical de Investigacion y Ensenanza Catie
2017
Faculty (United Kingdom)
2014
Hospital Roberto del Rio
2012
Harvard University
2007
Fundación Chile
2007
Millennium Science Initiative
2002
Commuters' exposure to PM<sub>2.5</sub>and ultrafine particles above background levels was observed in Santiago, Chile, which varied with transport mode.
Abstract Particle infiltration is a key determinant of the indoor concentrations ambient particles. Few studies have examined influence particle composition on infiltration, particularly in areas with high volatile particles, such as ammonium nitrate (NH4NO3). A comprehensive monitoring study was conducted 17 Los Angeles–area homes. As part this study, indoor/outdoor concentration ratios during overnight (nonindoor source) periods were used to estimate fraction particles remaining airborne...
The impact of outdoor and indoor pollution sources on air quality in Santiago, Chile was investigated. Toward this end, 16 homes were sampled four sessions. Each session included an site using different unvented space heaters (electric or central heating, compressed natural gas, liquefied petroleum kerosene). Average fine particulate matter (PM2.5) concentrations very high (55.9 microg x m(-3)), a large fraction these particles penetrated indoors. PM2.5 several components (including sulfate,...
Abstract The transition from controlled to partial support ventilation is a challenge in acute respiratory distress syndrome (ARDS) patients due the risks of patient-self-inflicted lung injury. magnitude tidal volume (V T ) and intrapulmonary dyssynchrony (pendelluft) are suggested mechanisms We conducted prospective, observational, physiological study tertiary academic intensive care unit. ARDS transitioning were included. On these, we evaluated association between changes inflammatory...
Abstract Background Internal redistribution of gas, referred to as pendelluft, is a new potential mechanism effort-dependent lung injury. Neurally-adjusted ventilatory assist (NAVA) and proportional ventilation (PAV +) follow the patient’s respiratory effort improve synchrony compared with pressure support (PSV). Whether these modes could prevent development pendelluft PSV unknown. We aimed compare magnitude during PAV + NAVA versus in patients resolving acute distress syndrome (ARDS)....
Abstract Santiago, Chile, is one of the most polluted cities in South America. As a response, over past 15 yr, numerous pollution reduction programs have been implemented by environmental authority, Comisión Nacional del Medio Ambiente. This paper assesses effectiveness these interventions examining trends fine particulate matter (PM2.5) and its associated elements. Daily particle filter samples were collected Santiago at downtown location from April 1998 through March 2003. Additionally,...
Ultrafine particle pollution is a health concern in indoor and outdoor settings. Reducing ultrafine exposure concentrations populated areas therefore an important research topic. Our study assesses the effectiveness of plants to decrease environments. Ambient were measured for three hours outside polycarbonate chamber with without using condensation counter. Reduction ambient levels between blanks treatments 11 plant species compared infiltration factors ( F infs ). All but one species,...
Little research has been done to evaluate the occupational health of electronic waste (e-waste) recycling workers in Latin America. The objective this study was complete comprehensive evaluations on e-waste Chile and compare those that work informal (i.e., independent) formal established company) settings. A cross-sectional summer 2017 recruited 78 from two cities 15 a single facility assess exposures outcomes. Participants completed questionnaire underwent full assessment. Herein, only data...
The Toxicological Evaluation of Realistic Emissions Source Aerosols (TERESA) study was carried out at three US coal-fired power plants to investigate the potential toxicological effects primary and photochemically aged (secondary) particles using in situ stack emissions. exposure system designed successfully simulated chemical reactions that plant emissions undergo a plume during transport from receptor areas (e.g., urban areas). Test atmospheres developed for experiments included scenarios...
Our approach to study multi-pollutant aerosols isolates a single emissions source, evaluates the toxicity of primary and secondary particles derived from this simulates chemical reactions that occur in atmosphere after emission. Three U.S. coal-fired power plants utilizing different coals with emission controls were evaluated. Secondary organic aerosol (SOA) α-pinene and/or ammonia was added some experiments. Male Sprague-Dawley rats exposed for 6 h filtered air or atmospheric mixtures....
In vivo chemiluminescence (CL) is a measure of reactive oxygen species in tissues. CL was used to assess pulmonary and cardiac responses inhaled aerosols derived from aged emissions three coal-fired power plants the USA. Sprague–Dawley rats were exposed either filtered air or: (1) primary (P); (2) ozone oxidized (PO); (3) + secondary organic aerosol (SOA) (POS); (4) neutralized SOA (PONS); (5) control scenarios: absence particles (OS), alone (O), (S). Immediately after 6 hours exposure, lung...
The Toxicological Evaluation of Realistic Emission Source Aerosols (TERESA) project assessed primary and secondary particulate by simulating the chemical reactions that a plume from source might undergo during atmospheric transport added other constituents interact with it. Three coal-fired power plants different coal emission controls were used. Male Sprague-Dawley rats exposed for 6 h to either filtered air or aged aerosol plant. Four exposure scenarios studied: particles (P); + (oxidized)...