- Multiple Sclerosis Research Studies
- Cerebral Palsy and Movement Disorders
- Autoimmune and Inflammatory Disorders Research
- Effects of Vibration on Health
- Balance, Gait, and Falls Prevention
- Stroke Rehabilitation and Recovery
- Peripheral Neuropathies and Disorders
- Fungal Infections and Studies
- Vestibular and auditory disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- T-cell and Retrovirus Studies
- Amyotrophic Lateral Sclerosis Research
- Long-Term Effects of COVID-19
- Systemic Sclerosis and Related Diseases
- Rheumatoid Arthritis Research and Therapies
- Scoliosis diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Hearing Loss and Rehabilitation
- Powdery Mildew Fungal Diseases
- Ophthalmology and Eye Disorders
- Assistive Technology in Communication and Mobility
- Myofascial pain diagnosis and treatment
- Optical Imaging and Spectroscopy Techniques
- COVID-19 and Mental Health
- Viral Infections and Immunology Research
Tel Aviv University
2016-2025
Sheba Medical Center
2016-2025
Univerzitetski Klinički Centar Srbije
2023
Multiple Sclerosis Society
2023
Universitat Autònoma de Barcelona
2023
University of Belgrade
2023
General University Hospital in Prague
2022
Charles University
2022
University of Cagliari
2020
Haukeland University Hospital
2018
Evaluation of treatment effects on walking requires appropriate and responsive outcome measures.To determine responsiveness 5 measures provide reference values for clinically meaningful improvements, according to disability level, in persons with multiple sclerosis (pwMS).Walking tests were measured pre- postrehabilitation 290 pwMS from 17 European centers. Combined anchor- distribution-based methods determined objective short long capacity (Timed 25-Foot Walk [T25FW] 2- 6-Minute Tests [2MWT...
Multiple sclerosis (MS) is a multi-focal progressive disorder of the central nervous system often resulting in diverse clinical manifestations. Imbalance appears most people with multiple (PwMS). A popular balance training tool virtual reality (VR) several advantages including increased compliance and user satisfaction. Therefore, aim this pilot RCT (Trial registration number, date: ISRCTN14425615, 21/01/2016) was to examine efficacy 6-week VR program using computer assisted rehabilitation...
Evaluate the effects of a Pilates exercise programme on walking and balance in people with multiple sclerosis compare this approach to conventional physical therapy sessions.Randomized controlled trial.Multiple Sclerosis Center, Sheba Medical Tel-Hashomer, Israel.Forty-five sclerosis, 29 females, mean age (SD) was 43.2 (11.6) years; Expanded Disability Status Scale (S.D) 4.3 (1.3).Participants received 12 weekly training sessions either ( n=22) or standardized n=23) an outpatient...
Abstract Falls are highly prevalent in people with multiple sclerosis (MS) and result a range of negative consequences, such as injury, activity curtailment, reduced quality life, increased need for care time off work. This narrative review aims to summarize key literature discuss future work needed the area fall prevention MS. The incidence falls MS is estimated be more than 50%, similar that adults older 80 years. consequences considerable because rate injury high, fear falling low...
Background and Purpose: Muscular gait abnormalities are common complaints among persons with multiple sclerosis, even in the early stages of disease. Our aim was to evaluate peak isometric strength, major lower limb muscle fatigue, spatiotemporal parameters a first neurological event suggestive defined as clinically isolated syndrome (CIS). Methods: Fifty-two individuals (36 women, 16 men) CIS, aged 35.2 (SD = 7.2) an Expanded Disability Status Scale score 1.7 1.3), participated study. Peak...
Context: Fatigue is one of the most common and disabling symptoms multiple sclerosis (MS); however, there no medication that has been approved specifically to treat MS-related fatigue. Objective: We aimed evaluate effect vitamin D analogue, Alfacalcidol, on Design, settings, participants: This was a randomized, double-blind, parallel group, placebo-controlled trial in patients with clinically definite MS by McDonald criteria conducted single university-affiliated medical center Israel....
Exercise as a subset of physical activity is cornerstone in the management multiple sclerosis (MS) based on its pleotropic effects. There an exponential increase quantity research exercise MS, yet number barriers associated with study content and quality hamper rapid progress field. To address these accelerate discovery, new international partnership MS-related experts has emerged goal advancing agenda. As first step, expert panel met May 2018 identified most urgent areas for moving field...
Regular physical activity (PA) helps to reduce the severity of and mental symptoms improves quality life in people with multiple sclerosis (PwMS). Based on current evidence expert opinion, recent guidelines recommend at least 150 minutes/week PA. This study presents results a survey analyzing whether how PwMS met before during pandemic.We developed disseminated an international online between December 2020 July 2021, investigating changes self-reported PA type, duration, frequency, intensity...
The primary aim was to examine the relationship between seven definite aspects of cognition measured by a computerized cognitive testing tool on history falls in people with mild moderate MS (PwMS). Secondary aims focused whether performance is correlated fear falling, walking velocity, and patient-rated measure ability. One hundred one PwMS were included study analysis. Fifty-two had at least fall during past year. Outcome measures test battery designed evaluate multiple domains, gait...
The importance of mobility impairments in people with multiple sclerosis (PwMS) denotes a need for valid, reliable, sensitive and feasible clinical measuring tools. Timed Up-and-Go (TUG) test is unique measure as it captures other functions apart from walking, i.e., rising out chair or turning around an object.To expand the construct validity TUG PwMS determine ability score to discriminate between four levels disability fallers, recurrent fallers non-fallers.Cross-sectional.Multiple...
Falls are a serious health concern for persons with multiple sclerosis (PwMS) who use wheelchairs or scooters as their primary mode of mobility. Unfortunately, little is known about the fall prevalence and characteristics this large segment (MS) community. The purpose study to determine circumstances falls in wheelchair scooter users living MS. Forty-four PwMS were recruited from research medical centers United States Asia. Participants completed survey focusing on falls, frequency injurious...
The aim was to compare the effectiveness of dual-task training (DTT) compared single mobility (SMT) on walking, and cognition, in persons with Multiple Sclerosis (pwMS). Forty pwMS were randomly assigned DTT or SMT groups. DTT-group performed exercises using an interactive tablet-based application, while SMT-group received conventional walking balance exercises. Both interventions supervised identical weeks (8) sessions (20). Nine cognitive-motor conditions assessed at baseline, after...
Background Gait characteristics and their changes during the 6-minute walking test (6MWT) in people with multiple sclerosis (pwMS) have been described literature, which one may refer to as fatigability body function level of International Classification Functioning, Disability, Health. However, whether these metrics are reliable is unknown. Objective To investigate between-day reliability gait pwMS healthy controls (HCs). Methods Forty-nine (EDSS 4.82 ± 1.22 54.7 9.36 years) 23 HCs (50.6 6.1...
Background: Upper limb dysfunction is common in people with multiple sclerosis (pwMS), significantly affecting daily activities and quality of life. While dalfampridine has shown efficacy improving gait pwMS, its impact on upper extremity function remains unclear. Objectives: To evaluate the effect sustained-release oral pwMS. Design: A randomized, placebo-controlled trial. Methods: In all, 30 pwMS were randomized to receive either (10 mg twice daily) or a placebo for 2 weeks. was assessed...
Accurate finger function assessment is crucial for monitoring the performance of daily hand activities. However, specialized digital applications are lacking evaluating various tasks. This study aims to develop a custom biosensing application assess dexterity. We developed compatible with smartphones and tablets that enables 3-min testing dexterity, measuring velocity accuracy each movement orientation. Data were collected dominant from large cohort healthy volunteers establish population...
Background and Objective . Treadmill gait analysis has been proposed as an attractive alternative for overground walking measuring systems. The purpose of this study was twofold: first to determine spatiotemporal parameters treadmill in patients with multiple sclerosis (MS) second examine whether these are associated specific functional impairments cohort. Method Eighty-seven relapsing-remitting diagnosed MS, 50 women 37 men, aged 40.9 ± 11.9 expanded disability status scale (EDSS) score 2.7...