A5101970747- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Geochemistry and Elemental Analysis
- Heavy Metal Exposure and Toxicity
- Intraocular Surgery and Lenses
- Liver Disease Diagnosis and Treatment
- Retinal Diseases and Treatments
- Trace Elements in Health
- Liver Disease and Transplantation
- Retinal Development and Disorders
- Radioactive element chemistry and processing
- Glaucoma and retinal disorders
- Cerebrospinal fluid and hydrocephalus
- Alzheimer's disease research and treatments
- Ophthalmology and Visual Impairment Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Retinal and Macular Surgery
- MRI in cancer diagnosis
- Retinal Imaging and Analysis
- Renal cell carcinoma treatment
- Aluminum toxicity and tolerance in plants and animals
- Electrochemical Analysis and Applications
- Connexins and lens biology
- Molecular spectroscopy and chirality
- Chromium effects and bioremediation
Gaozhou People's Hospital
2019-2023
Southwest Hospital
2012-2021
Army Medical University
2012-2021
Shandong First Medical University
2013
Jinan City People's Hospital
2013
Chinese Academy of Sciences
2000-2007
Institute of High Energy Physics
2000-2007
PerkinElmer (United States)
2007
Jiaozuo University
2002
PURPOSE Lenvatinib (LEN) is a first-line therapy for patients with advanced hepatocellular carcinoma (HCC); however, it has shown modest survival benefits. Therefore, we aimed to compare clinical outcomes of LEN combined transarterial chemoembolization (LEN-TACE) versus monotherapy in HCC. MATERIALS AND METHODS This was multicenter, randomized, open-label, parallel group, phase III trial. Patients primary treatment-naive or initial recurrent HCC after surgery were randomly assigned (1:1)...
Nicotine reduces beta-amyloidosis and has a beneficial effect against Alzheimer's disease (AD), but the underlying mechanism is not clear. The abnormal interactions of beta-amyloid (Abeta) with metal ions such as copper zinc are implicated in process Abeta deposition AD brains. In present study, we investigated nicotine on homeostasis hippocampus cortex APP(V717I) (London mutant form APP) transgenic mice. A significant reduction contents senile plaques neuropil observed after treatment....
This study aims to compare the safety and effectiveness between transarterial chemoembolization (TACE) with drug-eluting beads (DEB-TACE) conventional TACE (cTACE) using lipiodol-based regimens in HCC patients a transjugular intrahepatic portosystemic shunt (TIPS).This retrospective included patent TIPS who underwent from January 2013 2019 that received either DEB-TACE (DEB-TACE group, n = 57) or cTACE (cTACE 62). The complications, liver toxicity, overall survival (OS), time progression...
Abstract Aims To investigate the efficacy and safety of lenvatinib idarubicin‐loaded drug‐eluting beads transarterial chemoembolization (IDADEB‐TACE) in primary advanced hepatocellular carcinoma (HCC). Methods This retrospective study included patients with HCC who received either monotherapy or plus IDADEB‐TACE as first‐line treatment from September 2019 to 2020 at three institutes. Overall survival (OS), time progression (TTP), objective response rate (ORR), adverse events were compared....
Purpose of the study: Age-related macular degeneration (AMD) is most common cause irreversible vision loss. Fibulin-5 (FBLN5) plays a pleiotropic role in pathogenesis AMD. We examined whether vitro overexpression FBLN5 retinal pigment epithelial (RPE) cells alters proliferation and migration cocultured choroidal endothelial (CECs) explored possible mechanisms involved.Materials methods: A recombinant lentiviral vector carrying Fbln5 gene was generated to transduce rat RPE cells. The...
Abstract Purpose Visual outcomes after cataract surgery in diabetic patients with retinal or visual pathway disease are difficult to predict as the fundus may be obscured, and assessment of potential is challenging. This study assessed value electrophysiology a prognostic indicator recovery cataract, prior surgery. Methods Forty-one (aged 52–80; 74 eyes) 13 age-matched non-diabetic control (21 were examined Pre-surgical examinations included best-corrected acuity (BCVA), slit-lamp...
We describe a case of bilateral cataract surgery in 56-year-old man following presbyopia laser situ keratomileusis. The preoperative refraction was −2.00 the right eye and −0.75 × 105 left eye. On last examination, uncorrected distance visual acuity 20/80 that can be corrected to 20/20 with −2.25 eye, whereas for reading 20/40 +2.25. His monovision design previous cornea also taken into consideration phacoemulsification posterior chamber intraocular lens (IOL) implantation. Two-step is...
493 Background: To compare the efficacy and safety of sorafenib plus transarterial chemoembolization (SOR-TACE) versus alone as postoperative adjuvant therapy for hepatocellular carcinoma (HCC) patients with portal vein thrombus (PVTT). Methods: This was a phase III, multicenter, randomized, control clinical trial. Eligible HCC PVTT were included randomly assigned (1:1) to receive SOR-TACE or therapy. Sorafenib treatment started within 3 days after randomization, an initial dose 400mg twice...
Purpose . To report the outcome of sutured intrascleral posterior chamber intraocular lens (PC IOL) fixation with ciliary sulcus location guided by ultrasonic biological microscopy (UBM). Methods Patients who underwent a PC IOL were reviewed and divided into four groups. In group 1, traditional (2 mm from limbus) was performed. groups 2, 3, 4, UBM performed before surgery to locate position as haptics insertion position. power selected decreasing calculated value 1.0 D, 0.5 0.0 respectively....
Abstract Purpose: To investigate the effectiveness and safety of combination sorafenib drug-eluting bead transarterial chemoembolization (DEB-TACE) in treatment early intrahepatic stage-progressed advanced hepatocellular carcinoma (ISPA-HCC). Methods: This study was approved by ethics committees six tertiary medical centers China. Between October 2017 2020, 213 patients with HCC received either combined on-demand DEB-TACE (DTS group, n = 103) or monotherapy (S 110). Overall survival (OS),...