Fang Liu

ORCID: 0000-0001-8038-8532
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About
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Research Areas
  • Insect and Arachnid Ecology and Behavior
  • Insect and Pesticide Research
  • Neurobiology and Insect Physiology Research
  • Plant and animal studies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Yersinia bacterium, plague, ectoparasites research
  • CRISPR and Genetic Engineering
  • Reproductive biology and impacts on aquatic species
  • Genomics and Rare Diseases
  • Diabetes Management and Research
  • Mitochondrial Function and Pathology
  • Metaheuristic Optimization Algorithms Research
  • Zoonotic diseases and public health
  • Liver physiology and pathology
  • Viral Infectious Diseases and Gene Expression in Insects
  • Biopolymer Synthesis and Applications
  • Cancer and Skin Lesions
  • Sperm and Testicular Function
  • Genomic variations and chromosomal abnormalities
  • Genetic and rare skin diseases.
  • Plant Reproductive Biology
  • Genetic factors in colorectal cancer
  • Genetic diversity and population structure
  • Dermatological and Skeletal Disorders
  • Insect Resistance and Genetics

Institute of Zoology
2020-2024

Guangdong Academy of Sciences
2020-2024

Inner Mongolia Comprehensive Disease Prevention and Control Center
2021-2024

Shaoxing People's Hospital
2024

University of Maryland, Baltimore
2023

Stanford University
2023

Chinese Academy of Fishery Sciences
2022

Ministry of Agriculture and Rural Affairs
2022

Children's Hospital of Fudan University
2022

Leibniz Institute of Plant Genetics and Crop Plant Research
2020

Abstract Bradysia odoriphaga and difformis are devastating pests of vegetable, ornamental crops edible mushrooms causing significant losses. Temperature may be an important factor restricting their population abundance in the summer. To determine effects short-term heat shock on adults, survival, longevity fecundity data were collected, antioxidant responses protein expression levels examined. Our results indicated that survival rates adults decreased rapidly after ≥36 °C, reproductive...

10.1038/s41598-017-13560-4 article EN cc-by Scientific Reports 2017-10-11

Although gene duplications provide genetic backup and allow genomic changes under relaxed selection, they may potentially limit flow. When different copies of a duplicated are pseudofunctionalized in genotypes, incompatibilities can arise their hybrid offspring. such cases have been reported after manual crosses, it remains unclear whether occur nature how affect natural populations. Here, we identified four duplicated-gene based including one previously not within an artificial Arabidopsis...

10.1093/molbev/msaa306 article EN cc-by Molecular Biology and Evolution 2020-11-24

The molting hormone 20-hydroxyecdysone (20E) plays a key role in insect development, metamorphosis, and reproduction. Previous studies have shown that ecdysteroid metabolism is regulated by series of CYP genes most the species. However, roles these Coleopteran beetle, Aethina tumida (small hive SHB) not yet been explored.In current study, we identified seven (six Halloween one AtCYP18A1 gene) related to 20E metabolism. Reverse transcription quantitative polymerase chain reaction (RT-qPCR)...

10.1002/ps.7146 article EN Pest Management Science 2022-08-23

Summary: Sertoli-Leydig cell tumors (SLCT) comprise less than 1% of ovarian tumors. The nature the Leydig cells has been a subject controversy and it is unclear whether they are clonally related to neoplasm or instead proliferate as non-neoplastic response Sertoli-cell component. Twelve SLCT were identified hematoxylin eosin unstained sections prepared from formalin-fixed, paraffin-embedded tissue blocks. Tissue samples microdissected normal tissue, Sertoli component, tumor component using...

10.1097/pgp.0b013e31802f3100 article EN International Journal of Gynecological Pathology 2007-10-01

BTB and CNC homology 1 (BACH1) regulates biological processes, including energy metabolism oxidative stress. Insufficient liver regeneration after hepatectomy remains an issue for surgeons. The Pringle maneuver is widely used during induces ischemia/reperfusion (I/R) injury in hepatocytes. A rat model of two-thirds partial with repeated I/R treatment was to simulate clinical maneuver. Delayed recovery function the clinic impaired were observed. Highly elevated lactate levels, along reduced...

10.1016/j.bcp.2024.116377 article EN cc-by Biochemical Pharmacology 2024-06-19

The occurrence of androgenic endocrine disrupting chemicals (EDCs) in water is thought to be linked deviation from normal male developmental and reproductive functions exposed aquatic organisms. Because environments represent a chemically complex medium, the combined effects EDCs require urgent attention. In present study, two model androgen receptor (AR) antagonists, flutamide (FLU), vinclozolin (VIN), were first determined individually Japanese medaka using transcriptional response for...

10.1002/tox.22163 article EN Environmental Toxicology 2015-06-22

Abstract Background As an important catecholamine neurotransmitter in invertebrates and vertebrates, dopamine plays multiple roles the life of honey bee. Dopamine receptors (DA), which specifically bind to activate downstream cascades, have been reported be involved bee reproduction, division labour, as well learning motor behaviour. However, how regulate behavior remains uninvestigated. Results The expression level Amdop 2 brain increased with age worker bees, was just opposite trend...

10.1186/s12983-023-00519-7 article EN cc-by Frontiers in Zoology 2023-12-18

Varroa destructor is by far the most serious threat to western honey bee, Apis mellifera. A screen bottom board, a cultural method for mite control, modified board with that allows mites fall onto sticky or grass soil below screen. Whether not can reduce varroa significantly has been controversial. Most studies show trend of lower populations in colonies these boards, but results are usually statistically significant. To understand whether negative have due small sample sizes, because...

10.3390/insects11090624 article EN cc-by Insects 2020-09-11

Brain transcriptional regulatory network for behavior demonstrates that brain gene expression in the honey bee can be accurately predicted from transcription factors (TFs), but roles specific TFs are less understood. Mushroom bodies (MBs) important learning, memory and sensory integration brain. A TFs, Mblk-1, expressed preferentially large-type Kenyon cells of honeybee MBs is to involved function by regulating its target genes bee. However, mechanism regulation still obscure. Here we show...

10.1111/1744-7917.12971 article EN Insect Science 2021-09-28

There were a total of 4 and 3 human plague cases that occurred in the Inner Mongolia Autonomous Region 2019 2020, respectively, with 1 2 deaths 2020 which indicated still poses significant threat to health especially for farmers, shepherds, or residents living native foci.On August 14, 2021, patient from Otog Qi (County) sought treatment Yinchuan City (the capital Ningxia Hui Region), where was diagnosed bubonic secondary septicemic plague. The genetic source tracking associated...

10.46234/ccdcw2021.267 article EN China CDC Weekly 2021-01-01

Abstract DNA methylation plays a significant role in transducing external environmental signals to cellular response reptiles; however, whether the patterns are conserved across species remains unclear. Here, we examined genome-wide differentiation between male and female hatchling gonads of temperature-dependent sex determination (TSD) Mauremys mutica (M. mutica) using methylation-dependent restriction-site associated sequencing (MethylRAD-seq) test differentially methylated genes...

10.1093/biolre/ioac142 article EN Biology of Reproduction 2022-07-14

Abstract During the pupal‐adult eclosion process of holometabolous insects, old cuticle is shed and replaced by a completely different new that requires tanning expansion, along with extensive extracellular matrix (ECM) remodeling. In vertebrates, metalloproteinases (MMPs), class zinc‐dependent endopeptidases, play key roles in regulating ECM surrounds cells. However, little known about these proteinases available insects. The small hive beetle (SHB), Aethina tumida , widespread invasive...

10.1111/1744-7917.13274 article EN Insect Science 2023-09-26

In recent years, symbiosis as a rich source of potential engineering applications and computational model has attracted more attentions in the adaptive complex systems evolution computing domains. Inspired by different symbiotic coevolution forms nature, this paper proposed series multi-swarm particle swarm optimizers called PS2Os, which extend single population optimization (PSO) algorithm to interacting multi-swarms constructing hierarchical interaction topologies enhanced dynamical update...

10.1016/j.sjbs.2017.01.033 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2017-01-25

Kabuki syndrome (KS) is a rare genetic disorder characterized by dysmorphic facial features, skeletal abnormalities, and intellectual disability. KMT2D KDM6A were identified as the main causative genes. To our knowledge, there exist no cases of KS, which reported with pneumorrhagia. In this study, 10-month-old male was diagnosed to have KS typical anomalies, serious postnatal growth retardation. Whole exome sequencing trio family revealed presence de novo missense variant (c.15143G > A, p....

10.3389/fped.2022.933693 article EN cc-by Frontiers in Pediatrics 2022-08-26

According to WHO, plague, caused by Yersinia pestis, has resurged since 2000. Inner Mongolia, harboring a quarter of China's plague foci, accounted for 80% national cases in the past five years. Despite its pivotal role Chinese epidemiology, genetic diversity and transmission dynamics Y. pestis this region remain under-investigated. Our analysis 585 strains from Mongolia (1948-2021) revealed three primary lineages, with 2.MED3 being predominant. We further delineated seven sub-phylogroups...

10.1038/s42003-024-07190-6 article EN cc-by-nc-nd Communications Biology 2024-11-09

Objective To enhance the understanding of fulminant type 1 diabetes (FT1DM). Methods Clinical and laboratory data 3 patients diagnosed as FT1DM in our hospital from January 2007 to March 2008 were retrospectively analyzed. Results (1)All cases males aged 29 43 years old with body mass index ranged 21.5 23.3 kg/m2. (2)They developed ketoacidosis rapidly after appearance diabetic symptoms 2–4 days. One case had a cardiac arrest. (3) At stage onset, plasma glucose level above 38...

10.3760/cma.j.issn.1674-5809.2009.01.011 article EN Chin J Diabetes Mellitus 2009-02-27

A 48-year-old female presented with a 6-year history of papules and plaques all over the body 1-year blurred vision in right eye.Physical examination showed porcelain-white atrophic peripheral erythematous halo telangiectnsia.She also suffered from exotropia,visual deterioration,visual field defects eye,as well as numbness left index finger,thumb anterior tibia.Skin biopsies abdominal lesions revealed dermal necrosis mucoid degeneration,inflammatory infiltration predominated by lymphocytes...

10.3760/cma.j.issn.0412-4030.2012.08.009 article EN Chinese Journal of Dermatology 2012-08-15
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