A5108050258- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Imaging and Diagnostics
- Computational Drug Discovery Methods
- Advanced X-ray and CT Imaging
- Lung Cancer Treatments and Mutations
- Cancer-related molecular mechanisms research
- Acute Myocardial Infarction Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Medical Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Viral gastroenteritis research and epidemiology
- Pancreatic and Hepatic Oncology Research
- Lymphoma Diagnosis and Treatment
- Microbial Natural Products and Biosynthesis
- Health disparities and outcomes
- Herbal Medicine Research Studies
- Spectroscopy and Laser Applications
- Fungal and yeast genetics research
- Ultrasound Imaging and Elastography
- Traditional Chinese Medicine Studies
- Lipid metabolism and biosynthesis
- Digital Radiography and Breast Imaging
- Phosphodiesterase function and regulation
South China Agricultural University
2025
Beijing University of Technology
2025
Qingdao University
2023-2025
Beijing Children’s Hospital
2024
Capital Medical University
2024
Army Medical University
2024
Chinese People's Liberation Army
2024
Foshan University
2024
Xiangtan University
2024
Tsinghua University
2012-2024
The precise control of gene regulation, and hence, correct spatiotemporal tissue patterning, is crucial for plant development. Plant microRNAs can constrain the expression their target genes at posttranscriptional levels. Recently, microRNA396 (miR396) has been characterized to regulate leaf development by mediating cleavage its GROWTH-REGULATING FACTOR (GRF) targets. miR396 also preferentially expressed in flowers. However, function flower unclear. In addition narrow leaves, pistils with a...
Rhodococcus opacus strain PD630 (R. PD630), is an oleaginous bacterium, and also one of few prokaryotic organisms that contain lipid droplets (LDs). LD important organelle for storage but intercellular communication regarding energy metabolism, yet a poorly understood cellular organelle. To understand the dynamics using simple model organism, we conducted series comprehensive omics studies R. including complete genome, transcriptome proteome analysis. The genome encodes 8947 genes are...
Chronic pain may accompany immune-related disorders with an elevated level of serum IgG immune complex (IgG-IC), but the underlying mechanisms are obscure. We previously demonstrated that IgG-IC directly excited a subpopulation dorsal root ganglion (DRG) neurons through neuronal Fc-gamma receptor I (FcγRI). This might be mechanism linking to and hyperalgesia. The purpose this study was investigate signaling pathways transduction channels activated downstream FcγRI. In whole-cell recordings,...
The outbreak of human infection due to the novel swine-origin influenza A (H1N1) virus began in Mexico March 2009. As July 6, 2009, more than 94 000 laboratory-confirmed cases were reported over 100 countries, including 7983 Canada. In this report, we describe epidemiologic and clinical characteristics first cluster human-to-human transmission new
Background/Objectives: Phosphodiesterase 7 (PDE7), a member of the PDE superfamily, selectively catalyzes hydrolysis cyclic adenosine 3',5'-monophosphate (cAMP), thereby regulating intracellular levels this second messenger and influencing various physiological functions processes. There are two subtypes PDE7, PDE7A PDE7B, which encoded by distinct genes. PDE7 inhibitors have been shown to exert therapeutic potentials in neurological respiratory diseases. However, FDA-approved drugs based on...
Although natural ventilation can effectively control the indoor air quality and thermal comfort, single-sided in isolation hotels may lead to transmission of virus-laden aerosols between windows on same façade but different floors near pollution source. Hereinafter, this kind is referred as inter-flat transmission. The configuration building a key factor influencing risk. This study took into account various attachment scenarios including flat façades (with no attachments), outdoor units...
Background/Objectives: Phosphodiesterase 7 (PDE7), a member of the PDE superfamily, selectively catalyzes hydrolysis cyclic adenosine 3′,5′-monophosphate (cAMP), thereby regulating intracellular levels this second messenger and influencing various physiological functions processes. There are two subtypes PDE7, PDE7A PDE7B, which encoded by distinct genes. PDE7 inhibitors have been shown to exert therapeutic effects on neurological respiratory diseases. However, FDA-approved drugs based...
In this paper, we use a two-stage sparse factorization approach for blindly estimating the channel parameters and then source components electroencephalogram (EEG) signals. EEG signals are assumed to be linear mixtures of components, artifacts, etc. Therefore, raw data matrix can factored into product two matrices, one which represents mixing other component matrix. Furthermore, in time-frequency domain, i.e., is time frequency domain. It challenging task estimate Our extensive analysis...
This study aimed to develop a deep learning-based model simultaneously perform the objective response (OR) and tumor segmentation for hepatocellular carcinoma (HCC) patients who underwent transarterial chemoembolization (TACE) treatment. A total of 248 from two hospitals were retrospectively included divided into training, internal validation, external testing cohort. network consisting an encoder pathway, prediction pathway was developed, named multi-DL (multi-task learning), using...
In myocardial T1 mapping, undesirable motion poses significant challenges because uncorrected can affect estimation accuracy and cause incorrect diagnosis. this study, we propose evaluate a correction method for mapping using self-supervised deep learning based registration with contrast separation (SDRAP). A sparse coding was first proposed to separate the component from -weighted (T1w) images. Then, neural network cross-correlation (SDRAP-CC) or mutual information as similarity measurement...
We investigated the influence of apolipoprotein B gene (APOB) variants on risk hyperlipidemia (HL) in 631 middle-aged and elderly members Chinese Yugur population (HL, n=336; normolipidemia, n=295). APOB polymorphisms were identified using mass spectrometry, five single nucleotide (rs1042034, rs2163204, rs512535, rs676210, rs679899) serum lipids further analyzed. rs1042034 rs676210 significantly associated with HL (P<0.05). Compared GG or AA genotype, individuals AG AG+AA AG+GG had a...
Purpose To propose a reconstruction framework to generate accurate T 1 maps for fast MR mapping sequence. Methods A deep learning–enhanced method with spatial‐temporal and physical constraint (DAINTY) was proposed. This explicitly imposed low‐rank sparsity constraints on the multiframe ‐weighted images exploit correlation. neural network used efficiently perform as well denoise reduce undersampling artifacts. Additionally, build bridge between learning prior, so benefits of constrained can...
Support vector machines (SVM) are applied to the prediction of key state variables in bioprocesses, such as product concentration and biomass concentration, which commonly play an important role bioprocess monitoring control. A so-called rolling learning-prediction procedure is used deal with time variant property process, establish training database for SVM predictor, characterized update database. As example, industrial penicillin production predicted, a comparison also made three...
Structure-based virtual screening plays a critical role in drug discovery. However, numerous docking programs, such as AutoDock Vina and Glide, are time-consuming due to the necessity of generating molecular conformations executing steps like scoring, ranking, refinement for ligand-receptor complexes. Consequently, achieving rapid reliable remains noteworthy challenge. Recently, team researchers from Massachusetts Institute Technology, led by Stärk et al., developed an SE(3)-equivariant...
As a common method for preparing micron powder in industrial operations, the mechanical extrusion simply pursues particle size without considering microstructure characteristics of sepiolite, which leads to problems such as bundles sepiolite not being effectively dispersed, and thus disruption fibers is inevitably caused. In this work, new micronization disaggregating these while preserving original structural integrity proposed based on steam pressure changes. The effects changes...
Goose astrovirus (GoAstV) is a novel avastrovirus that typically causes gosling gout and results in 2 to 20% mortality. GoAstV capsid protein the sole structural protein, which responsible for viral attachment, assembly, maturation as well eliciting host antibodies. However, epitopes within have not been studied. In this study, monoclonal antibody, named 1D7, was generated against by hybridoma technology. Western blot showed MAb could react with recombinant expressed E. coli. Also, it...
In order to provide communication services in delay/fault-tolerant mobile sensor network (DFT-MSNs) for pervasive information gathering where it lacks end-to-end paths between the sources and sink, a variety of forwarding routing schemes have been proposed. Consequently, is significant accurately evaluate performance show their advantages inferiority. At same time, energy very limited, serious problem DFT-MSNs practice, impacts system significantly. However, current existing works evaluation...