A5030672072- Acute Myeloid Leukemia Research
- RNA Research and Splicing
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Cancer-related cognitive impairment studies
- Immune Cell Function and Interaction
- Histone Deacetylase Inhibitors Research
- Immune cells in cancer
- Antifungal resistance and susceptibility
- Lymphoma Diagnosis and Treatment
- MicroRNA in disease regulation
- Cancer Immunotherapy and Biomarkers
- Pneumocystis jirovecii pneumonia detection and treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Lung Cancer Research Studies
- Parasitic Diseases Research and Treatment
First Affiliated Hospital of Xinjiang Medical University
2021-2025
Xinjiang Medical University
2021-2025
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, with significant clinical heterogeneity. Recent studies suggest that intratumoral microbiome may influence tumor microenvironment, affecting patient prognosis and therapeutic responses. This study aims to identify microbiome-related subtypes in DLBCL assess their impact on prognosis, immune infiltration, sensitivity. Transcriptomic data from 48 patients were obtained public databases. Consensus...
Acute myeloid leukemia (AML) is a group of heterogeneous hematological malignancies. We identified key genes as ITGAM and lncRNA ITGB2-AS1 through different bioinformatics tools. Furthermore, qPCR was performed to verify the expression level essential in clinical samples. Retrospective research on 179 AML cases used investigate relationship between characteristics AML. The critical gene with immune infiltration estimated. validation prognostic investigation showed that ITGAM, PPBP, are...
Background: Acute Myeloid Leukemia (AML) is a complex and heterogeneous hematologic malignancy. However, the function of prognosis-related signature genes in AML remains unclear. Methods: In current study, transcriptome sequencing was performed on 15 clinical samples, differentially expressed RNAs were identified using R software. The potential interactions network constructed by common between target miRNAs with results. Functional pathway enrichment analysis to identify candidate...
Based on a few studies, heart failure patients with breast cancer were assessed to find potential biomarkers for doxorubicin-induced cardiotoxicity. However, key immune-related transcriptional markers linked cardiotoxicity in have not been thoroughly investigated. We used GSE40447, GSE76314, and TCGA BRCA cohorts perform this study. Then, we performed various bioinformatics approaches identify the their association cancer. found 255 upregulated genes 286 downregulated discovered that...
Acute myeloid leukemia (AML) is a type of hematological malignancy with diverse genetic pathogenesis. Identification the miR-93-5p targeted pathogenic markers could be useful for AML diagnosis and potential therapy. We collected 751 AML-related genes by integrating results multiple databases then used expression profile TCGA-LAML to construct coexpression function network WGCNA. Based on clinical phenotype module trait relationship, we identified two modules (brown yellow) as interesting...