A5090793084- Toxic Organic Pollutants Impact
- Per- and polyfluoroalkyl substances research
- Atmospheric chemistry and aerosols
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Chromatography
- Computational Drug Discovery Methods
- Spectroscopy and Chemometric Analyses
- Metabolomics and Mass Spectrometry Studies
- Effects and risks of endocrine disrupting chemicals
- Physics of Superconductivity and Magnetism
- Analytical chemistry methods development
- Magnetic and transport properties of perovskites and related materials
- Superconducting Materials and Applications
- Contact Dermatitis and Allergies
- Water Treatment and Disinfection
- Chemistry and Chemical Engineering
- Inorganic Fluorides and Related Compounds
- Microplastics and Plastic Pollution
- Water Quality and Resources Studies
- Environmental Toxicology and Ecotoxicology
- Odor and Emission Control Technologies
- Water Quality and Pollution Assessment
- Chromatography in Natural Products
- Water Quality Monitoring and Analysis
- Fish Ecology and Management Studies
National Institute of Advanced Industrial Science and Technology
2015-2024
University of Tsukuba
2022
National Institute for Environmental Studies
2012-2018
Yokohama National University
2003-2016
Tokyo University of Agriculture and Technology
2011
Pollution from 35 perfluorinated compounds (PFCs) in the water of Tokyo Bay basin was examined. The contained relatively high levels perfluorononanoate (PFNA), perfluorooctanoate (PFOA), and perfluorooctane sulfonate (PFOS) compared to other PFCs, which were present at concentrations 20.1 ng/L, 6.7 5.8 respectively. In contrast, their precursors degradation products an order magnitude lower. Sewage treatment plant (STP) effluent area also PFNA with river samples (Mann−Whitney U-test, p <...
Perfluorinated compounds (PFCs) have been detected in a wide range of places. They also reported to come from nonpoint sources, but the origin these sources has not identified. In present study, we attempted characterize source PFCs Hayabuchi River, Japan, which runs through an urban area, using geographic information system (GIS) and statistical analysis. We estimated annual PFC loads Japan as whole, determining magnitude comparable that sewage treatment plants (STPs); was few tons per year...
We estimated inflow rates of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) to Tokyo Bay, Japan, between February 2004 2011 by a receptor-oriented approach based on quarterly samplings the bay water. Temporal trends in these are an important basis for evaluating changes PFOS PFOA emissions Bay catchment basin. A mixing model average concentrations compounds freshwater bay, which were then multiplied obtain compounds. The enabled us comprehensively cover including via direct...
A global spectral deconvolution, based on non-negative matrix factorization (NMF) in comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry, was developed. We evaluated the ability of various instrumental parameters and NMF settings to derive high-performance detection nontarget screening using a sediment sample. To evaluate performance process, NIST library search used identify deconvoluted spectra. Differences scan rates (25 50 Hz) deconvolution...
With advances in machine learning (ML) techniques, the quantitative structure–activity relationship (QSAR) approach is becoming popular for evaluating chemicals. However, QSAR requires that chemical structure of target compound known and it should be convertible to molecular descriptors. These requirements lead limitations predicting properties toxicities chemicals distributed environment as PubChem database; structural information on only 14% compounds available. This study proposes a new...
Abstract The experimental values of skin permeability coefficients, required for dermal exposure assessment, are not readily available many chemicals. existing estimation approaches either less accurate or require parameters that available. Furthermore, current methods easy to apply complex environmental mixtures. We present two models estimate the coefficients neutral organic first model, referred here as 2-parameter partitioning model (PPM), exploits a linear free energy relationship...
Thousands of organohalogen compounds, including hazardous chemicals such as polychlorinated biphenyls (PCBs) and other persistent organic pollutants (POPs), were selectively simultaneously detected identified with simple, or no, purification from environmental sample extracts by using several advanced methods. The methods used software extraction two-dimensional gas chromatography-high-resolution time-of-flight mass spectrometry (GC × GC-HRTofMS) data, measurement negative chemical...
Complex chemical mixtures need to be evaluated to, for example, aid in medical diagnoses, assess product quality, and environmental conditions. Two-dimensional gas chromatography (GC × GC), which is a comprehensive analytical technique, combined with data classification techniques, has attracted great interest assessing mixtures. In this study, nontarget cross-sample analysis-based unsupervised direct method using non-negative matrix factorization was developed analyzed by GC GC. The more...