A5059795686- CRISPR and Genetic Engineering
- Gene Regulatory Network Analysis
- Biomedical and Engineering Education
- Bioeconomy and Sustainability Development
- Biotechnology and Related Fields
- Genetically Modified Organisms Research
- Cell Image Analysis Techniques
- Interdisciplinary Research and Collaboration
- Innovative Approaches in Technology and Social Development
- Genetics, Bioinformatics, and Biomedical Research
- University-Industry-Government Innovation Models
- Higher Education and Employability
- Neuroethics, Human Enhancement, Biomedical Innovations
- Career Development and Diversity
- Biomedical Ethics and Regulation
- Cell Adhesion Molecules Research
- Immunotherapy and Immune Responses
- Innovation and Socioeconomic Development
- Climate Change Communication and Perception
- Scientific Computing and Data Management
- Social and Economic Solidarity
- Digital Imaging in Medicine
- International Relations and Autism
- Bacillus and Francisella bacterial research
- Transcranial Magnetic Stimulation Studies
Arizona State University
2015-2025
Institute for the Future
2017-2021
Behavioral Health Systems
2017
University of Edinburgh
2009-2015
Genomics (United Kingdom)
2009
University of Cambridge
2000-2004
Addenbrooke's Hospital
2000
In March 2014 a group of early career researchers and academics from São Paulo state the UK met at University Campinas to participate in workshop on 'Responsible Innovation Governance Socially Controversial Technologies'. this Perspective we describe key reflections observations discussions, paying particular attention discourse responsible innovation cross-cultural perspective. We number important tensions, paradoxes opportunities that emerged over three days workshop.
Based on criticism of the “ethical, legal and social implications” (ELSI) paradigm, researchers in science technology studies (STS) have begun to create move into “post-ELSI” spaces. In this paper, we pool our experiences working towards collaborative practices with colleagues engineering disciplines field synthetic biology. We identify a number different roles that taken, been assumed take, or had foisted upon us as sought develop post-ELSI practices. argue situation is characterised by...
In this paper we identify five rules of thumb for interdisciplinary collaboration across the natural and social sciences. We link these to efforts move away from 'ethical, legal issues' framework interdisciplinarity towards a post-ELSI collaborative space. It is in trying open up such space that need for: experimentation, taking risks, reflexivity, opening-up discussions unshared goals neighbourliness.
While the research community continues to develop novel proposals for intrinsic biocontainment of genetically engineered organisms, translation real-world deployment faces several challenges.
A prominent imaginary of synthetic biology is the sustainability bio-based technologies. In this paper, authors discuss various reports, papers, and activities in relation to a core set principles sustainability, paying particular attention concept “prudent vigilance” as introduced by report U.S. Presidential Commission for Study Bioethical Issues. The introduce two additional concepts – anticipatory governance transformational science outline an approach systematically incorporating...
The deployment of gene drives is emerging as an alternative for protecting endangered species, controlling agricultural pests, and reducing vector-borne diseases. This paper reports on a workshop held in February 2016 to explore the complex intersection political, economic, ethical, ecological risk issues associated with drives. Workshop participants were encouraged use systems thinking mapping describe connections among social, policy, variables they intersect within governance systems. In...
The widespread use of digital image-processing software to prepare images for publication is a matter growing unease among journal editors, particularly in the biosciences. Concerned not so much with intentional fraud, but rather routine and ‘innocent’ yet inappropriate alteration images, several high-profile science journals have recently introduced guidelines authors regarding image manipulation, are implementing in-house forensic procedures screening submitted images. Such interventions...
Synthetic biology represents a recent attempt to bring engineering principles and practices working with biology. In practice, the nature of relationship between in synthetic is subject ongoing debate. The disciplines are typically seen involve different ways knowing doing, embody assumptions objectives. Tensions these approaches playing out as field being established. Here, we study negotiations through International Genetically Engineered Machine (iGEM) competition. This undergraduate...
Recent accounts of “the biological” emphasize its thoroughgoing transformation. Accounts biomedicalization, biotechnology, biopower, biocapital, and bioeconomy tend to agree that twentieth- twenty-first-century life sciences transform the object biology, biological. Amidst so much transformation, we explore attempts stabilize biological through standards. We ask: how do standards handle in transformation? Based on ethnographic research, article discusses three contemporary postgenomic...
KEYWORDS: Gene drivebiotechnologysynthetic biologygenetic pest managementgovernance of emerging technologies
Synthetic biology represents a recent and explicit attempt to make easier engineer, through this open up the design space of genetic engineering wider range practitioners (including, but not limited to, engineers). Proponents approach emphasize standardization practices as key successful biological engineering; yet, meaningful transatlantic differences are emerging with respect constitution concerns governance synthetic in United States (US) Kingdom (UK). In article, I tease out how national...
There are currently hundreds of businesses across the United States offering direct-to-consumer stem cell treatments that have not been through regulatory approval by Food and Drug Administration (FDA). Here, we provide a detailed characterization nearly 170 operating in Southwest States. We draw specific attention to two as-yet understudied facets these businesses. First, identify differences degree which given business focuses their practice on treatments. Second, compare stated expertise...
The cytokine transforming growth factor beta1 (TGF-beta1) is secreted in a latent form that has no known biological activity. conversion of TGF-beta1 into its biologically active 25 kDa thought to be an important step the regulation TGF-beta activity both cell culture and vivo. Thrombospondin (TSP)-1, 360 platelet alpha-granule extracellular matrix protein, been shown participate activation. We have used chemically defined system examine mechanism TSP-1-mediated However, addition two...