Abstract Background Medicaid expansion under the Affordable Care Act extends eligibility for participating states and has been associated with improved outcomes by facilitating access to care. Delayed initiation of adjuvant chemotherapy is worse among patients early-stage breast cancer (BC). The impact in narrowing delays race ethnicity not studied, our knowledge. Methods This was a population-based study using National Cancer Database. Patients diagnosed primary BC between 2007 2017...

PURPOSE Triple-negative breast cancer (TNBC) is a clinically aggressive subtype associated with poorer survival outcomes. We examined the patterns and trends in neoadjuvant chemotherapy (NACT) use, pathologic complete response (pCR), overall (OS). Furthermore, we evaluated association between pCR OS large cohort of patients. METHODS Patients aged 18 years older stage I-III TNBC diagnosed 2010 2021 were identified National Cancer Database. Trends NACT pCR, assessed using Cochran-Armitage test...

<h3>Importance</h3> Patients who are uninsured and belong to racial ethnic minority groups or have low socioeconomic status suboptimal access health care, likely affecting outcomes. The association of the Affordable Care Act's Medicaid expansion with survival among patients metastatic breast cancer is unknown. <h3>Objective</h3> To examine between mortality disparity de novo stage IV cancer. <h3>Design, Setting, Participants</h3> Cross-sectional, population-based study using Cox proportional...

(Neo) adjuvant chemotherapy decreases the risk of recurrence and improves overall survival among breast cancer patients; however, delays in initiation are associated with adverse health outcomes. The causes delay complex include interrelated social, economic, cultural, environmental, system factors. Project Start was a qualitative study designed to assess identify multilevel factors contributing barriers facilitators initiating chemotherapy.Women diagnosed primary invasive who experienced...

Abstract Background: The use of capecitabine in the adjuvant setting patients with residual disease after neoadjuvant chemotherapy has been incorporated into practice based on results CREATE-X trial. We evaluate utilization patterns use, its association outcomes, and subsequent hospitalizations emergency room (ER) visits among elderly early-stage triple-negative breast cancer (TNBC). Methods: identified aged ≥66, diagnosed TNBC between 2010 2017 SEER Texas Cancer Registry (TCR)-linked...

Abstract Background: Patterns of adjuvant and neoadjuvant chemotherapy use among patients with breast cancer have changed over time. Historically, has been the standard treatment approach for triple-negative after surgical resection, aiming to eliminate any remaining cells reduce risk recurrence. Advancements in strategies, research findings, clinical guidelines contributed shifts care approaches, an increase chemotherapy. In this study, we explore utilization a large cohort elderly...

602 Background: TNBC is associated with clinically aggressive behavior and poorer survival outcomes. Among patients TNBC, the use of NACT offers several advantages including improved outcomes among those who achieve a pathological complete response (pCR). We examined patterns use, trends pCR, association between pCR overall (OS) in large cohort patients. Methods: Patients ≥18 years stage I-III diagnosed 2010-2020 underwent surgery received chemotherapy were identified National Cancer...

Objective: We evaluated the association between Medicaid expansion and time to surgery among patients with early-stage breast cancer (BC) Summary Background Data: Delays in are associated adverse outcomes. It is known that underrepresented minorities more likely experience treatment delays. Understanding impact of on reducing racial ethnic disparities healthcare delivery critical. Methods: This was a population-based study including women ages 40-64 stage I-II BC who underwent upfront...

255 Background: Although the association between delays in (neo)adjuvant chemotherapy initiation and adverse outcomes is well-documented, research into what those with breast cancer experience during their delay sparse. This information can provide insight for newly diagnosed women on preparing inform potential interventions to facilitate initiation. study aimed assess identify multilevel factors contributing barriers facilitators of initiating chemotherapy. We present a qualitative...

Although the association between delays in (neo)adjuvant chemotherapy initiation and adverse outcomes is well-documented, patient perspective regarding lived experience among those with breast cancer delay sparse. Project Start was a qualitative study designed to assess identify multilevel factors contributing barriers facilitators of initiating chemotherapy. This report explores specific responses where patients provide insight advice for newly diagnosed women on preparing informs potential...

6525 Background: Inadequate access to healthcare services is associated with worse outcomes. Disparities in cancer care are more frequently seen among racial/ethnic minorities, uninsured patients, and those low socioeconomic status. A provision the Affordable Care Act called for expansion of Medicaid eligibility order cover low-income Americans. In this study, we evaluate impact 2-year mortality metastatic BC patients according race. Methods: Women (aged 40-64) diagnosed (stage IV de novo)...

247 Background: (Neo)Adjuvant chemotherapy decreases the risk of recurrence and improves overall survival among breast cancer patients; however, delays in initiation are associated with adverse outcomes. The causes delay complex include interrelated social, economic, cultural, environmental, health system factors . Project Start was a qualitative study designed to assess identify multilevel contributing barriers facilitators initiation. Methods: English or Spanish-speaking women, ≥18 years,...