- Superconducting Materials and Applications
- Physics of Superconductivity and Magnetism
- Characterization and Applications of Magnetic Nanoparticles
- Breast Cancer Treatment Studies
- Particle accelerators and beam dynamics
- Superconductivity in MgB2 and Alloys
- Magnetic Properties and Applications
- Breast Lesions and Carcinomas
- MRI in cancer diagnosis
- Geomagnetism and Paleomagnetism Studies
- Advanced MRI Techniques and Applications
- HVDC Systems and Fault Protection
- Radiomics and Machine Learning in Medical Imaging
- Microfluidic and Bio-sensing Technologies
- Advanced Radiotherapy Techniques
- Neural dynamics and brain function
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Hyperthermia Applications
- Magnetic properties of thin films
- Particle Accelerators and Free-Electron Lasers
- Magnetic and transport properties of perovskites and related materials
- Colorectal Cancer Surgical Treatments
- Nanoparticle-Based Drug Delivery
- Photoreceptor and optogenetics research
- Breast Implant and Reconstruction
University of Twente
2016-2025
Imagerie et Cerveau
2014-2020
The Netherlands Cancer Institute
2018
Institute of Engineering Physics
2016
Czech Academy of Sciences, Institute of Physics
2016
Wilhelmina Children's Hospital
2013
University Medical Center Utrecht
2013
Norfolk and Norwich University Hospitals NHS Foundation Trust
2013
Royal Cornwall Hospital Trust
2013
University College Hospital
2013
We review the scaling relations for critical current density (Jc) in Nb3Sn wires and include recent findings on variation of upper field (Hc2) with temperature (T) A15 composition. highlight deficiencies Summers/Ekin relations, which are not able to account correct Jc(T) dependence. Available Jc(H) results indicate that magnetic dependence all can be described Kramer's flux shear model, if non-linearities Kramer plots attributed inhomogeneities. The strain (eps) is introduced through a...
To determine if prostatitis and prostate cancer (PCa) can be distinguished by using apparent diffusion coefficients (ADCs) on magnetic resonance (MR) images, with specimens obtained at MR-guided biopsy as the standard of reference.The need for institutional review board approval informed consent was waived. biopsies were performed in 130 consecutive patients cancer-suspicious regions (CSRs) multiparametric MR images 3 T. In this retrospective study, 88 met inclusion criteria. During...
MRI scanners enable fast, noninvasive, and high-resolution imaging of organs soft tissue. The images are reconstructed from NMR signals generated by nuclear spins that precess in a static magnetic field B0 the presence gradients. Most clinical operate at = 1.5 T, corresponding to proton resonance frequency 64 MHz. Because these systems rely on large superconducting magnets, they costly demanding infrastructure. On other hand, low-field imagers have potential be less expensive, confining,...
Detection of tumor metastases in the lymphatic system is essential for accurate staging malignancies. Commercially available superparagmagnetic nanoparticles (SPIOs) accumulate normal lymph tissue after injection at a site, whereas less or no accumulation takes place metastatic nodes, thus enabling using MRI. We verify first time potential SPIOs, such as Endorem® novel photoacoustic (PA) contrast agent biological tissue. injected five Wistar rats subcutaneously with variable amounts and...
Purpose To evaluate if a three-component model correctly describes the diffusion signal in kidney and whether it can provide complementary anatomical or physiological information about underlying tissue. Materials Methods Ten healthy volunteers were examined at 3T, with T2-weighted imaging, tensor imaging (DTI), intravoxel incoherent motion (IVIM). Diffusion parameters (mean diffusivity [MD] fractional anisotropy [FA]) obtained by iterative weighted linear least squares fitting of DTI data...
Recent experiments in rats have shown the occurrence of a high amplitude slow brain wave EEG approximately 1 minute after decapitation, with duration 5–15 s (van Rijn et al, PLoS One 6, e16514, 2011) that was presumed to signify death neurons. We present computational model single neuron and its intra- extracellular ion concentrations, which shows physiological mechanism for this observation. The is caused by membrane potential oscillations, occur cessation activity sodium-potassium pumps...
Sentinel lymph node biopsy (SLNB) with a superparamagnetic iron oxide (SPIO) tracer was shown to be non-inferior the standard combined technique in SentiMAG Multicentre Trial. The MRI subprotocol of this trial aimed develop magnetic alternative for pre-operative lymphoscintigraphy (LS). We evaluated feasibility using following administration localization sentinel nodes (SLNs) and its potential non-invasive identification (LN) metastases.Patients breast cancer scheduled undergo SLNB were...
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Highlights•Accurate localisation is essential for breast conserving surgery of non-palpable tumours.•A novel magnetic technology (MaMaLoc) introduced.•Fifteen cancer patients are treated with the technology.•The found feasible and safe, negligible marker migration.AbstractObjectivesAccurate tumour breast-conserving tumours. Current technologies associated disadvantages such as logistical challenges migration issues (wire guided localisation) or legislative complexities high administrative...
To compare the clinical benefit of robust optimized Intensity Modulated Proton Therapy (minimax IMPT) with current photon Radiation (IMRT) and PTV-based IMPT for head neck cancer (HNC) patients. The is quantified in terms both Normal Tissue Complication Probability (NTCP) target coverage case setup range errors.For 10 HNC patients, IMRT (7 fields), minimax (2, 3, 4, 5 7 fields) plans were tested on robustness. Robust differed from that they CTV penalize possible error scenarios, instead...
Strain effects on critical current densities have been examined for conductors containing nearly stoichiometric Nb3Al filaments with fine grains. The phase in these multifilamentary are prepared by transformation from supersaturated Nb(Al) bcc solid solution and show high-field much larger than those conventionally conductors, where the is known to be off-stoichiometric. degradation of −0.7% intrinsic strain ca. 20% at 12 T, comparable conventional high tolerance.
Due to their shape anisotropy, high aspect ratio magnetic nanoparticles offer many advantages in biomedical applications. For biocompatibility, it is essential have full control over the dimensions and surface chemistry of particles. The aim this study was synthesize biocompatible nanowires with tuneable dimensions. This achieved by electrodeposition Ni polycarbonate membranes. To ensure a continuous gold coating deposited onto wires newly developed electroless deposition method. analysed...
<h3>BACKGROUND AND PURPOSE:</h3> Both hemodynamics and aneurysm wall thickness are important parameters in pathophysiology. Our aim was to develop a method for semi-quantitative assessment on vivo 7T MR images of intracranial aneurysms studying the relation between apparent shear stress. <h3>MATERIALS METHODS:</h3> Wall analyzed 11 unruptured 9 patients who underwent imaging with TSE-based vessel sequence (0.8-mm isotropic resolution). A custom analysis program determined intensities, which...
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Various Nb/sub 3/Sn conductors are investigated in an axial strain experiment. The superconducting samples soldered to a substrate that is bent generate compressive or tensile strain. Especially the range critical current reduction smaller than predicted by well-known scaling law. influence of transverse components tape conductor changing thermal It found experiments can be described upper-critical field depends on deviatoric component tensor only. Finally comparison temperature and as...