(1) To describe repair of complex orbital fractures using computer planning with preoperative virtual reconstruction, mirror image overlay, endoscopy, and surgical navigation. (2) test the hypothesis that this technique improves outcomes in fractures. A series 113 consecutive severe fracture cases was analyzed, 56 which were performed overlay guidance, 57 repaired without. Data collected on patient characteristics, severity, diplopia globe position outcomes, complications, need for revision...

Twenty-year retrospective review of 14,102 spine surgeries.To determine the incidence perioperative ischemic optic neuropathy (POION) in surgery at our institution.In recent years, vision loss patients undergoing has become an issue increasing concern to physicians, patients, and medicolegal experts. The POION been addressed two separate studies that found incidences 0% 0.12%.We performed a 20-year database search for all who underwent had concurrent ICD-9 discharge diagnosis pertaining...

Uveal melanomas frequently metastasize and cause patient death. Many clinical, histopathologic, molecular, genetic factors have been linked to metastasis. We hypothesized that understanding the relationships between, relative prognostic significance of these would provide new insights into pathogenesis To this end, we collected pathologic, molecular data for 65 uveal melanomas, including age, sex, tumor size, location, cell type, vasculogenic mimicry looping matrix patterns, gene expression...

Purpose: Soft tissue ischemia is a devastating and unpredictable complication following dermal filler injection. Multiple mechanisms to explain this have been proposed, including vascular compression, vessel damage, intraarterial emboli. To elucidate the mechanism of injury, authors introduce mouse model, imaged with optical microangiography laser speckle contrast imaging technologies, demonstrate in vivo microvascular response soft intravascular Methods: determine effect external...

The eyebrows and eyebrow fat pads, key structures in upper facial aesthetics, are particularly vulnerable to age-related changes.In this study, the authors compare impact of aging on pad volume men women through three-dimensional (3D) volumetric analysis.Electronic medical records patients seen at Jules Stein Eye Institute Division Orbital Ophthalmic Plastic Surgery between 2005 2010 were reviewed. Patients included if they had undergone investigative imaging orbit for unilateral pathology....

Clinical, radiographic, and molecular studies have shown that patients with thyroid-associated orbitopathy exhibit volumetric expansion of eyebrow tissues. This clinicopathologic entity has been termed periorbitopathy. The goal this study was to determine whether high-resolution ultrasonography could be used reliably quantify periorbitopathy.Institutional review board approval obtained. internal case-control consisted 12 subjects unilateral-asymmetric orbitopathy. High-resolution using a...

Canine bites frequently result in periocular injury. The authors aimed to further characterize the dog breeds, types of injuries inflicted, and treatment outcomes.A retrospective chart review was performed on all recorded University Washington trauma registry from 2003 2013. Cases involving ocular injury were investigated identify tissues affected, patterns, total 342 bite victims identified, whom 91 sustained (27%). mean age patients with significantly lower than those without (14.1 ± 1.9...

Orbital decompression for thyroid-associated orbitopathy (TAO) is commonly performed disfiguring proptosis, congestion, and optic neuropathy. Although one typically achieves goals, a small percentage requires repeat decompression. We 10-year retrospective chart review of all orbital decompressions TAO at single tertiary referral institution. Four-hundred ninety-five orbits (330 patients) were decompressed TAO, with 45 (37 requiring reviewed the cases indications, clinical activity scores,...

Classically, the aesthetic outcomes of eyelid retraction surgery in patients with thyroid-associated orbitopathy have been described reference to margin position and marginal reflex distance. A critically important component upper contour is tarsal platform show (TPS). With this study, authors aimed assess hypothesis that modification posterior has a significant effect on final outcome.In retrospective, observational, case-cohort reviewed medical records 36 who underwent primary by 1...

To report a series of patients with herpes zoster ophthalmicus and associated acute orbital syndrome corresponding radiographic findings.Medical records 7 findings were reviewed. Clinical presentation, radiography, treatment outcomes assessed.One man 6 women median age 70 years (range 47-84) presented clinical signs. Two the had compromised immune systems, 1 patient having chronic lymphocytic leukemia another infected human immunodeficiency virus. included proptosis, blepharoptosis,...

Secondary acquired nasolacrimal duct obstruction (SANDO), where the is caused by a known process, becoming more commonly treated endoscopic dacryocystorhinostomy (endoDCR). This study evaluates outcomes of endoDCR for cases SANDO in comparison to treating primary (PANDO).All patients undergoing from 2006 2015 at tertiary referral center were reviewed etiology (NLDO) and success procedure. Inclusion criteria preoperative determination NLDO via probing irrigation, greater than 60-day follow up...

Both granular and lattice deposits are present in Avellino corneal dystrophy (ACD), primarily associated with the R124H mutation of transforming growth factor-β-induced (TGFBIp). We investigated presence these other TGFBI mutations use Thioflavin-T (ThT), a fluorescent amyloid stain for characterizing deposits.Surgical specimens 3 unrelated patients clinically diagnosed ACD were studied. Corneal sections from normal individuals prior (LCD) used as controls. Histochemical studies performed...

Objectives: To determine whether indications for keratoplasty differ between academic centers and the Eye Bank Association of America (EBAA) annual statistics from 2002 to 2012. Methods: A retrospective review was performed 2012 based on surgical specimens originating three different centers. Data were compared with statistical reports obtained EBAA corresponding years. Results: From 2007, at Washington University in St Louis (WU), most common indication graft failure 31.6%. At University,...

Ligneous conjunctivitis is a rare, autosomal recessive, membranous characterized by deficiency in type 1 plasminogen. The absence of normal plasmin activity results the formation fibrin-rich, material that typically manifests on palpebral conjunctiva. Surgical treatment often causes irritation conjunctiva and accelerated recurrence pseudomembranes. In this interventional case report, authors document with topical plasminogen following conjunctival pseudomembrane excision 32-year-old woman....

To present the experience and outcomes of orbital fracture repair using Lorenz titanium implants in one tertiary care center.Five-year retrospective chart review 55 patients who underwent with since 2002. The following data were recorded: age; gender; mechanism injury; prior repair; concomitant ocular injuries; time elapsed between injury surgery; preoperative postoperative visual acuity, diplopia, extraocular motility, Hertel exophthalmometry. All CT. Operative included surgical approach,...

Purpose: The Sonopet Ultrasonic Aspirator is a surgical tool that uses low-frequency ultrasonic vibrations to fragment tissue while simultaneously irrigating and aspirating the field. This technology becoming more widely used in orbital, lacrimal, neurological, skull base surgery, but few studies have examined learning curve associated with adoption of this technology. We present our curve, pearls, pitfalls using newest generation Universal handpiece endoscopic dacryocystorhinostomy (eDCR)...

To evaluate ophthalmic complications and quantitatively assess anatomic changes following maxillectomy with or without adjuvant radiotherapy in patients midface malignancy.Twenty-four who underwent for sinus and/or paranasal cancer were included retrospective review. Patients complete examinations evaluated postoperative findings corresponding to sequelae of treatment. When available, anatomical including eyelid position quantified from preoperative full-face photos using computer...

To investigate the possible mutations in carbohydrate sulfotransferase 6 (CHST6) gene of 2 unrelated cases macular corneal dystrophy (MCD) and to report atypical stromal deposits one them.Corneal tissues were stained with antisulfated keratan sulfate (KS), antitransforming growth factor beta 1-induced protein (TGFBIp), thioflavin-T, alcian blue, Masson trichrome. Sequencing was performed identify potential CHST6 fourth twelfth exons TGFBI gene.Alcian blue staining revealed presence multiple...

Volume enhancement/restoration addresses a key component of facial aging and plays an increasingly central role in rejuvenation. Advancing our understanding the structure morphology aging—and changes that can be induced with currently-available fillers—will optimize treatment provide consensus for appropriate selection agents procedures. By elucidating anatomic relationships—particularly dynamic relationships—ultrasonography may facilitate application rejuvenation procedures such as lower...