Insulin lispro is a human insulin analog that dissociates more rapidly than regular after subcutaneous injection, resulting in higher levels at an earlier point time and shorter duration of action. The aim the study was to evaluate if this pharmacokinetic difference would translate into better postprandial overall control 30 IDDM patients (age, 35.1 ± 1.5 years; male-female ratio, 17:13; BMI, 24.8 0.5 kg/m2; HbA1c, 8.03 0.13% baseline) treated with continuous infusion (CSII; Disetronic...

OBJECTIVE—To evaluate glycemic control, hypoglycemic events, and quality of life in patients treated with continuous subcutaneous insulin infusion (CSII) multiple daily injection (MDI), lispro as the principal insulin. RESEARCH DESIGN AND METHODS—This clinical trial enrolled 27 type 1 diabetes. They were randomly assigned to CSII (n = 13) or MDI 14) treatment regimens. Glycemic control (HbA1c level) was primary outcome measured monthly for 9 months. Secondary outcomes patient reports events...

The glucoregulatory and hormonal responses to moderate-intensity exercise (50% VO2max for 45 min) were examined in subjects with type 2 diabetes mild hyperglycemia. We studied seven obese lean control (fasting plasma glucose levels, 7.5 +/- 0.5, 4.8 0.1, 5.2 0.1 mmol/l, respectively). Glucose production, utilization, cycling (flux between glucose-6-phosphate [G-6-P]) measured [6-(3)H]glucose [2-(3)H]glucose using the constant specific-activity method. Insulin levels decreased normally during...

Introduction Using students in the Liangshan Yi autonomous prefectures of southwestern China ( n = 585; 13–15 years old), we examined (i) effects students’ perception their teachers’ ethnic-racial socialization on ethnic identity and mental health outcomes depressive stress symptoms; (ii) (iii) differential associations among these factors minority versus Han cultural majority students. Methods We conducted a cross-sectional survey used multistage sampling to collect information....

Exercise is frequently recommended in the treatment of diabetes mellitus. Recent studies have improved our understanding acute and long-term metabolic hormonal effects physical activity both healthy controls people with diabetes. In insulin-dependent mellitus (IDDM), exercise, itself, does not a significant effect on overall glycemic control should be encouraged primarily for its nonglycemic benefits. Hypoglycemia predominant risk associated exercise individuals IDDM can reduced by adjusting...

To determine whether the long-term use of insulin lispro (LP) affects counterregulatory hormone response to hypoglycemia.Ten patients (age range 26-51 years; ratio men women 9:1; BMI 24.9 +/- 0.48; mean HbA1c 7.84 0.25%) with IDDM, treated continuous subcutaneous infusion (CSII; Disetronic H-TRON V100) were studied using a double-blind, crossover design. Patients randomized LP or human regular (HR) for 3 months and then crossed over other an additional months. All meal boluses given 0-5 min...

Health-care professionals who offer perinatal bereavement support often encountered numerous stressful events in daily practices. Secondary trauma and burnout related to psychological distress are not uncommon. Literatures suggested that further skill training enhances perceived self-competence thus lowering such traumatic impact. Nevertheless, equanimity, an emerging concept professional development, which is characterized by a sense of unflappability resilience face challenges,...

This study explored how Chinese women with donor-assisted conception experienced loss of genetic continuity and managed conception–related information. Through Interpretative Phenomenological Analysis, a thematic framework on women’s beliefs, motivation, behaviors in information management was constructed. Contrary to the Western trend toward disclosure, it found that strongly preferred conceal, order protect their family members, parent–child relationship, stability. Participants’ strong...

Idiopathic hypercalciuria, though a common cause of nephrolithiasis, has not been recognized to hypocalcemia and severe bone disease. We describe an adolescent with idiopathic hypercalciuria who presented initially osteoporosis this was later complicated by recurrent renal calculi formation after calcium vitamin D supplement. After treatment thiazide, controlled serum biochemistry normalized. While may negative balance in adults, variant syndrome leak occurring growing subject could lead...

Intersexuality is a general term referring to an individual who born with reproductive anatomy that does not fit the typical gender binary system.It has always been mystery as very little information currently available public in Chinese community.It leaves society remain generally ignorant about existence of individuals intersex status, and turn, fear stigmatization exclusion by compels most affected conceal their personal information.Since it often frontline professionals, including...

We report a light-driven, catalytic protocol for the intramolecular hydroetherification of unactivated alkenols to furnish cyclic ether products. These reactions occur under visible light irradiation in presence an Ir(III)-based photosensitizer, Brønsted base catalyst, and hydrogen atom transfer co-catalyst. Reactive alkoxy radicals are proposed as key intermediates that generated by direct homolytic activation alcohol O–H bonds through proton-coupled electron mechanism. This method exhibits...