A5060346664- Geological and Geochemical Analysis
- Radioactive element chemistry and processing
- Sperm and Testicular Function
- Geochemistry and Elemental Analysis
- Chemical Synthesis and Characterization
- Clay minerals and soil interactions
- High-pressure geophysics and materials
- earthquake and tectonic studies
- Reproductive Biology and Fertility
- Crystal Structures and Properties
- Urologic and reproductive health conditions
- Autophagy in Disease and Therapy
- Erythrocyte Function and Pathophysiology
- Hormonal and reproductive studies
- Protease and Inhibitor Mechanisms
- Paleontology and Stratigraphy of Fossils
- Endoplasmic Reticulum Stress and Disease
- Groundwater and Isotope Geochemistry
- Cell death mechanisms and regulation
- Testicular diseases and treatments
- Stress Responses and Cortisol
- Extraction and Separation Processes
- Blood Coagulation and Thrombosis Mechanisms
- Retinal Development and Disorders
- Cell Adhesion Molecules Research
Nanjing University
2017-2023
Henan Polytechnic University
2022-2023
Chinese Academy of Sciences
2003-2009
Institute of Zoology
2003-2009
Context: The context of the study was to examine whether combined testosterone (T) and heat (H) treatment have additive or synergistic effects on suppression spermatogenesis. Objective: objective determine T+H induces a greater spermatogenesis than either alone in monkeys. Design: randomized, placebo-controlled study. Setting: conducted at primate center China. Participants: population comprised 32 adult cynomolgus Interventions: Groups eight monkeys were treated for 12 wk with: 1) two empty...
Male contraception has focused, to a great extent, on approaches that induce azoospermia or severe oligospermia through accelerated germ cell apoptosis. Understanding the specific steps in apoptotic pathways are affected by male contraceptives will allow more targeting future contraceptive development. In this study, we have used nonhuman primate model characterize key pathway(s) death after mild testicular hyperthermia, hormonal deprivation, combined interventions. Groups of 8 adult (7-...
This study investigates the role of caspase 2 in apoptotic signaling nonhuman primate male germ cells triggered by mild testicular hyperthermia, testosterone (T(e)) implants, or combined interventions. Mean incidence cell apoptosis increased significantly Day 3 heat (H(e)) alone group and 8 Te but peaked at H(e) + T(e) group. We found activation both Sertoli after induction apoptosis. Most notably, active immunoreactivity was detected only those susceptible to compared with controls, where...
To investigate the germ cell apoptosis under body temperature in testis, we analyzed gene expression patterns on day 1, 4, 7, 14, 28 and normal control adult mouse testis after experimental cryptorchidism (EC) using Affymetrix MOE430A microarray. Our data showed that EC led to oxidative stress fluctuation first days, both of which were highly coincident timing. Cryptorchid more effective antioxidative capability 4 suddenly lowered from 5 on, then gradually restored antioxidation 10 turned...
As a cell‐specific organelle, acrosome (Acr) and its formation are an important event for spermiogenesis. However, the Acr is far more complicated than has been proposed. In this study, we have cloned novel membrane protein Afaf (Acr associated factor) that was expressed abundantly in round spermatids, localized inner outer of forming Acrs, declined maturing Acrs. transfected Hela cells, plasma membrane, EEA1‐positive early endosomes (EEs) occasionally nuclei. Therefore, propose EEs may be...
Geothermal waters in the Shiquanhe-Yarlun Zangbo geothermal field of southern Tibet are highly enriched rare alkali metals (RAMs), which form a globally unique geyserite Cs-deposit. Boron isotopes, together with geochemistry local leucogranite, springs and were investigated to constrain migration accumulation RAMs cesium deposit. The δ11B values −9.4 ‰ −8.4 tourmalines from Himalayan leucogranite typical S-type granites. A mass balance calculation indicates that magma granite contained < 10...
Except for extensive studies in core formation and volatile-element depletion processes using radiogenic Ag isotopes (i.e., the Pd-Ag chronometer), recent research has revealed that mass fractionation of silver is principle controlled by physicochemical (e.g., evaporation, diffusion, chemical exchange, etc.) during magmatic emplacement hydrothermal alteration. As these geologic only produce very minor variations δ109Ag from -0.5 to +1.1‰, more accurate precise measurements are required. In...
The corpus luteum (CL) is a transient endocrine organ that secretes progesterone to support early pregnancy. Using primate materials obtained from rhesus monkeys, we have in this study investigated the expression and regulation of plasminogen activators (PAs) PA inhibitor type 1 (PAI-1) during CL development regression. Adult (5–7 yr old) female monkeys were treated with pregnant mare serum gonadotropin/human chorionic gonadotropin induce ovulation follicular luteinization. At various luteal...