A5053242153- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Ultrasound in Clinical Applications
- Glioma Diagnosis and Treatment
- Tracheal and airway disorders
- Retinoids in leukemia and cellular processes
- Congenital heart defects research
- Cancer-related Molecular Pathways
- Congenital Diaphragmatic Hernia Studies
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Pituitary Gland Disorders and Treatments
- Histone Deacetylase Inhibitors Research
- Thyroid Cancer Diagnosis and Treatment
- Microtubule and mitosis dynamics
- Mathematical Biology Tumor Growth
- Brain Metastases and Treatment
- Airway Management and Intubation Techniques
- Cancer Immunotherapy and Biomarkers
- Occupational and environmental lung diseases
- Radiomics and Machine Learning in Medical Imaging
- Genomics and Phylogenetic Studies
- Tissue Engineering and Regenerative Medicine
University of Naples Federico II
2024
Ceinge Biotecnologie Avanzate (Italy)
2024
University of Campania "Luigi Vanvitelli"
2020-2023
Malignant pleural mesothelioma (MPM) is an invasive, aggressive tumor with a predominantly local spread. The objective of this study was to assess thoracic ultrasound (TUS) as imaging modality high sensitivity for the identification malignant involvement and in order guide biopsies.In retrospective single-center between January 2018 June 2022, 51 consecutive patients impassable circumferential thickening underwent TUS at Thoracic Surgery Unit Vanvitelli University Naples. Pleural biopsies...
Video-assisted thoracic surgery (VATS) for ipsilateral reoperations is controversial, because after the first surgical intervention, pleural adhesions occur frequently in cavity and/or chest wall. This study assessed usefulness of preoperative ultrasonography to reduce incidence lung injury at time initial port insertion during secondary VATS.This was a retrospective, single-center study. Nine patients who underwent Vanvitelli Hospitalfrom September 2019 February 2022, were scheduled second...
Glioblastoma multiforme is one of the most frequent and aggressive primary tumors in central nervous system, representing >60% all brain adults. Despite treatment, prognosis remains poor with if not patients experiencing disease recurrence a 2-year survival rate 27%. At present, no confirmed standard treatment exists for recurrent glioblastoma. Regorafenib few options available, based on results from REGOMA trial. In present study, real-life retrospective investigation role regorafenib...
Purpose: ATTRACTION-2 trial assessed the role of Nivolumab as a new standard treatment for Asian patients with pretreated metastatic gastric cancer (mGC). The aim this analysis was to evaluate safety and efficacy in real-life Western population, considering lack evidence date. Patients Methods: progressed after ≥ 2 chemotherapy regimens able receive (3 mg/kg q14) were eligible analysis. Results: 16 received third (81.3%) or fourth line (18.7%) from September 2017 July 2019. literature only...
Abstract Introduction Central airway tumors involving the trachea and main‐stem bronchi are a common cause of obstruction significant mortality among patients thoracic diseases with respiratory failure. Debulking in rigid bronchoscopy is quick, safe, effective. It can be complex hard severe bronchial or tracheal and/or intraluminal bleeding because inadequate distal control. We have used laser tube as new technique ventilation for central obstruction. Materials Methods Forty‐six undergoing...
Glioblastoma multiforme (GBM) is one of the most frequent and aggressive primary tumors in central nervous system, representing more than 60% all brain adults. Primary GBM remains incurable with a poor prognosis both for limited therapeutic alternatives high risk progression or recurrence. In fact, at recurrence, few treatment options available, often characterized by effectiveness, have always been an Achilles' heel. The recent approval second line regorafenib, multikinase inhibitor, has...
Staging of the mediastinum lymph nodes involvement in patients with non-small cell lung cancer (NSCLC) is an important prognostic factor determining most appropriate multimodality treatment plan. The objective this study to assess ultrasound characteristics mediastinal metastasis and effectiveness intraoperative ultrasound-guided nodal dissection resected NSCLC.All undergoing video-assisted thoracoscopic surgery lobectomy pulmonary lymphadenectomy from November 2020 March 2022 at thoracic...
Abstract Introduction The brain-related phenotypes observed in 22q11.2 deletion syndrome (22q11.2DS) are highly variable and their origin is poorly understood. Changes brain metabolism may cause or contribute to the phenotypes, given that many of deleted genes (approx. 10%) implicated metabolic processes, but this currently unknown. It clearly important address knowledge gap, humans, primary material required for studying inaccessible. For reason, we sought issue using two mouse models...
Abstract OBJECTIVE Video-Assisted Thoracic Surgery (VATS) resection, of deep-seated and nodules smaller than 3 cm, is very hard.Solitary, small pulmonary are difficult to palpate or see during VATS. We aimed evaluated the validity Intraoperative lung ultrasound (ILU) visualize solitary cm enhance knowledge on morphological patterns. RESULTS US processor was inserted by expert surgeon into chest through operating hole, mediastinal, costal diaphragmatic surfaces were explored.VATS- Ultrasound...