A5100713969- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Corneal Surgery and Treatments
- Alzheimer's disease research and treatments
- Retinal and Optic Conditions
- Ocular Disorders and Treatments
- Connexins and lens biology
- Retinal and Macular Surgery
- Sharing Economy and Platforms
- Ocular Diseases and Behçet’s Syndrome
- Medicinal plant effects and applications
- Drug-Induced Ocular Toxicity
- Congenital Ear and Nasal Anomalies
- Erythrocyte Function and Pathophysiology
- Vascular Anomalies and Treatments
- Renal Diseases and Glomerulopathies
- Traumatic Ocular and Foreign Body Injuries
- Ocular Oncology and Treatments
- Retinal Diseases and Treatments
- Blood groups and transfusion
- Otitis Media and Relapsing Polychondritis
- Flavonoids in Medical Research
UNSW Sydney
2015-2025
Sree Gokulam Medical College and Research Foundation
2025
Boston Children's Hospital
2020-2024
Harvard University
2003-2024
Creative Commons
2023
Sardar Patel Medical College
2023
Boston Children's Museum
2020-2022
Jaypee Hospital
2020-2022
Narayana Nethralaya
2014-2021
Midnapore Medical College and Hospital
2021
To assess the repeatability and agreement of three rotating Scheimpflug cameras, Pentacam, Galilei, Sirius, in measuring mean keratometry (Km), thinnest corneal thickness (TCT), anterior chamber depth (ACD), posterior (pKm) keratoconus patients a prospective study.Fifty-five eyes 55 with underwent consecutive scans on each machine, performed by single operator. Within-subject standard deviation (Sw), test-retest (TRT), coefficient variation (COV) for assessing Bland-Altman plots between...
Abstract Aggregation prone molecules, such as tau, form both historically well characterized fibrillar deposits (neurofibrillary tangles) and recently identified phosphate-buffered saline (PBS) extract species called proteopathic seeds. Both can cause normal endogenous tau to undergo templated misfolding. The relationship of these seeds the fibrils that define tau-related diseases is unknown. We aqueous extractable sarkosyl insoluble derived from human Alzheimer brain using mass spectrometry...
To evaluate the relationship between central corneal thickness and intraocular pressure (IOP) measured by iCare rebound tonometry (RBT) in normals glaucomatous patients.Of 102 patients screened, we included 62 eyes with glaucoma 77 normal this hospital-based cross-sectional study. IOP was RBT which averages 6 readings followed Goldmann applanation (GAT). Central (CCT) obtained ultrasound pachymetry an average of 5 consecutive readings. Relationship CCT studied regression techniques using...
Purpose: The purpose of this study is to assess the repeatability and agreement five imaging devices, namely, Pentacam (Oculus), Sirius (CSO), Orbscan IIz (Bausch Lomb), Corvis ultrasound pachymetry (UP, Tomey) in measuring steep keratometry (sKm), flat (fKm), central corneal thickness (CCT), thinnest (TCT), anterior chamber depth (ACD) healthy individuals. Design: This was prospective, comparative study. Subjects: Forty-six Indian patients. Materials Methods: eyes 46 participants underwent...
Abstract Purpose To assess the repeatability of lipid layer thickness (LLT) measurement using LipiView® interferometer after daily disposable contact lens (CL) wear and correlation with ocular comfort in soft wearers. Methods A prospective study was conducted over two consecutive months, wherein CL wearers ( n = 20) wore either Somofilcon or Verofilcon CLs a crossover design, switching lenses 1 month. The pre‐corneal tear film LLT measured at end each month had been worn for least 6 h. Using...
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory involving 0.5–1% of the global population. Coexistence RA and thyroid dysfunction now increasingly being recognized. This due to shared factors involved in pathogenesis disease. Thyroid disorder an important amplifier disease activity, thereby impairing quality life. Objectives: To study prevalence pattern patients, compare activity among patients with those without dysfunction, possible association between severe...
Objectives: To establish a normative database for retinal nerve fiber layer (RNFL) thickness in children<18 years by spectral-domain optical coherence tomography (SD-OCT). Methods: Children <18 years, who were consecutively enrolled from July-August 2011 this cross-sectional hospital study, underwent Cirrus SD-OCT. Recorded demographics and clinical characteristics included age, sex, axial length, spherical equivalent, intraocular pressure (by Perkins tonometry) cup disc ratio. The RNFL full...
SIGNIFICANCE Modern highly oxygen-permeable nonfenestrated scleral lenses induce approximately 1 to 2% corneal edema after short periods of lens wear in healthy individuals. This study investigated the magnitude and regional variation lens-induced central penetrating keratoplasty. PURPOSE The purpose this was examine a period post–penetrating keratoplasty eyes control group with corneas. METHODS Nine (nine participants; mean age, 32 years) were fitted (Dk 100 × 10 −11 cm 3 O 2 (cm)/[(s) (cm...
To quantify the effect of a single scleral lens design on visual acuity and ocular higher-order aberrations in eyes with post-LASIK ectasia, keratoconus pellucid marginal degeneration (PMD) that could not achieve satisfactory vision spectacles or soft contact lenses.Forty-six 28 participants fitted diagnostic lenses (KeraCare) were analysed, including 19, 15 12 PMD, respectively. Corrected distance (CDVA) measured prior to wear during after 60 min settling. An i-Trace aberrometer was used...
Purpose: To compare and determine the repeatability of central corneal thickness (CCT) measurements using four noncontact pachymetry instruments in eyes with keratoconus. Materials Methods: The CCT consecutive patients keratoconus was measured during a single visit swept source optical coherence tomography (SS-OCT, Casia SS-1000°CT, Tomey, Nagoya, Japan), rotating Scheimpflug camera system (Pentacam, Oculus Optikgerate GmbH, Wetzlar, Germany), scanning slit topographer (Orbscan IIz...
A 17-year old boy, with decreased vision in right eye for 15 days, presented retinal periphlebitis multiple quadrants of the and partially active serpiginous-like choroiditis left eye. Tuberculin test was positive (16 mm induration), chest X-ray showed hilar lymphadenopathy. The patient treated a 9-month course anti-tubercular therapy tapering dose oral corticosteroids. Both vasculitis lesions resolved over 3-4 months. Retinal neovascularization laser photocoagulation. There no recurrence an...
Abstract Purpose Visual rehabilitation following penetrating keratoplasty is the primary indication for approximately 15% of all scleral lens fittings. Since corneal biomechanics are altered keratoplasty, aim this study was to quantify changes in anterior optics short‐term wear eyes with grafts. Methods Scheimpflug images were obtained before and after a period (mean 6.3 ± 1.4 h), from that had previously undergone (10 nine participants, mean age 31 9 years). Corneal power thickness data...
Objective: To compare corneal biomechanics and intraocular pressure (IOP) in keratoconus penetrating keratoplasty eyes before after nonfenestrated scleral lens wear. Methods: Twenty-three participants were enrolled, 37 included the analysis (11 26 keratoconus). A range of biomechanical parameters IOP measured using CORVIS ST 8 hr wear (Keracare, Acculens, Denver, CO). Results: Before wear, displayed significantly greater median values for central thickness (97 μm thicker, P =0.02), (3.89 mm...
Abstract Background Clinical studies have long observed that neurodegenerative disorders display a range of symptoms and pathological features and, in some cases, overlap, suggesting these diseases exist on spectrum. Dementia with Lewy Bodies (DLB), synucleinopathy, is prominent example, where symptomatic similarities tauopathy, Alzheimer’s disease, are observed. Although tau pathology has been DLB, the interplay between α-synuclein poorly understood at molecular level. Methods Quantitative...
We report two uncommon cases of acute onset myopia with macular folds following use topiramate. A 25‐year‐old woman, no prior history glasses, taking topiramate for recurrent headaches, presented decreased vision. On examination, she was found to have a refractive error ‐5.00-DS in both eyes and intraocular pressure 10-mmHg 6-mmHg the right left eyes, respectively. She had closed angles on gonioscopy, ciliary effusion ultrasonic biomicroscopy inner limiting membrane macula eyes....
Hand is a body part which of major importance for communication, language and social contact along with its basic function grasping feeling. Finger partial finger amputations are some the most frequently encountered forms hand loss causes devastating physical, psychosocial economic damage to an individual. Rehabilitation amputed utmost first choice microvascular reconstruction. But when it contraindicated, unavailable, unsuccessful or unaffordable, prosthetic rehabilitation alternative...
This study aims to report the use of mini-scleral contact lens in management mucous membrane pemphigoid (MMP) with persistent epithelial defects. A 68-year-old male a history ocular pain and declining visual acuity was referred our clinic diagnosis MMP. His corrected distance (CDVA) 20/200 right eye 20/100 left eye. Despite being on lubricants, topical steroids intravenous cyclophosphamide, patient developed corneal defects both eyes. He then given trial lenses. Within 4 weeks, healed, at 6...
There have been numerous reports of ocular manifestations blunt trauma. We describe a case hypotony due to cyclodialysis following injury with stone.A 41‐year‐old man presented c...
An eight-year-old boy presented with decreased vision in both eyes. At presentation, the visual acuity was 6/60 eyes high plus spheres. Anterior segment examination normal. Fundus and spectral domain optical coherence tomography were consistent posterior microphthalmos showed an elevated foveal contour fold outer plexiform layer. External limiting membrane, photoreceptor retinal pigment epithelium not involved fold. To best of our knowledge this is first such case report imaging layer a...
To quantify short-term changes in corneal high-order aberrations (HOA) with piggyback contact lens use an eye keratoconus that had undergone intrastromal ring segment (Intacs) implantation.A patient reporting of distorted images after Intacs surgery was found to have HOA (trefoil, point spread function [PSF], and modulation transfer [MTF]) as measured using wavefront technology (Nidek OPD-Scan III) evidenced by her cylindrical correction. She underwent (silicone hydrogel fluoroperm rigid...