Nelson D. Franqui-Ríos

ORCID: 0000-0001-8275-7741
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About
Contact & Profiles
Research Areas
  • Hedgehog Signaling Pathway Studies
  • Tumors and Oncological Cases
  • Oral and Maxillofacial Pathology

University of Puerto Rico-Mayaguez
2019

The paracrine interaction between tumor cells and adjacent stroma has been associated with the oncogenic activity of Hedgehog (Hh) pathway in triple-negative breast tumors. present study developed a model Hh signaling examined impact mesenchymal cell sources culture modalities oncogenicity cells. Studies consisted monocultures co-cultures cancer-associated normal fibroblasts, that undergo epithelial–mesenchymal transition (EMT), or adipose-derived stem (ADMSCs). ligand inhibitors, GANT61...

10.3390/cancers11101522 article EN Cancers 2019-10-10
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