A5004749664- Multiple Sclerosis Research Studies
- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cutaneous lymphoproliferative disorders research
- Polyomavirus and related diseases
- Peripheral Neuropathies and Disorders
- Systemic Lupus Erythematosus Research
- Nail Diseases and Treatments
- Genetic and rare skin diseases.
- Acute Lymphoblastic Leukemia research
- Dermatology and Skin Diseases
- Reproductive System and Pregnancy
- Cancer and Skin Lesions
- Musculoskeletal pain and rehabilitation
- Allergic Rhinitis and Sensitization
- Psoriasis: Treatment and Pathogenesis
- Dermatologic Treatments and Research
- Autoimmune Bullous Skin Diseases
- Pregnancy and Medication Impact
- Urticaria and Related Conditions
- COVID-19 and Mental Health
- Systemic Sclerosis and Related Diseases
- Long-Term Effects of COVID-19
- Heparin-Induced Thrombocytopenia and Thrombosis
University of Siena
2023-2025
Ospedale Santa Maria alle Scotte
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
Istituto Ortopedico Rizzoli
2020-2022
University of Ferrara
2020
University of Bari Aldo Moro
2009-2016
University of Florence
2014
Objective Postacute COVID-19 syndrome (PACS) is an emerging entity characterised by a large array of manifestations, including musculoskeletal complaints, fatigue and cognitive or sleep disturbances. Since similar symptoms are present also in patients with fibromyalgia (FM), we decided to perform web-based cross-sectional survey aimed at investigating the prevalence predictors FM who recovered from COVID-19. Methods Data were anonymously collected between 5 18 April 2021. The collection form...
To assess fetal risk after pregnancy exposure to natalizumab in women with multiple sclerosis (MS), a specific focus on spontaneous abortion (SA) and congenital anomalies (CA).Data of all pregnancies occurring between 2009 2015 patients MS treated referring 19 participating sites were collected compared those untreated injectable immunomodulatory agents. Rates SA CA also reported the Italian population. Multivariable logistic linear regression models performed.A total 92 tracked 83 women. In...
<h3>Objective</h3> To assess relapses, disability progression and the role of disease modifying drugs (DMDs) in year after delivery women with multiple sclerosis (MS). <h3>Methods</h3> We prospectively followed-up pregnancies occurring between 2002 2008 MS, recruited from 21 Italian MS centres. The risk relapses was assessed using time-dependent Cox regression analysis. <h3>Results</h3> 350 out 423 were (pregnancies not resulting live birth a postpartum follow-up period shorter than 1...
Rosacea is a common chronic inflammatory skin disorder that mainly affects the central face. It primarily characterized by recurrent episodes of flushing, persistent erythema, papules, telangiectasias, phymatous changes, and ocular symptoms. Its pathogenesis complex still not completely understood. encompasses innate adaptive immune system dysregulation, neurovascular dysfunction, genetic environmental factors. To date, four subtypes rosacea have been identified, based on predominant...
<h3>Objective</h3> To assess the risk of disease reactivation during pregnancy after natalizumab suspension in women with multiple sclerosis (MS). <h3>Methods</h3> Data all pregnancies occurring between 2009 and 2015 patients MS treated referring to 19 participating sites were collected compared those untreated injectable immunomodulatory agents through a 2-factor repeated measures analysis. Predictors activity assessed stepwise multivariable logistic regression models. <h3>Results</h3> A...
Background/Objectives: Eyelid dermatitis is an inflammatory disease affecting the palpebral skin characterized by itching, edema, and scaling of periorbital area. This entity can be a manifestation various underlying dermatological diseases, but allergic contact (ACD) predominant etiology eyelid among patients, being diagnosed in 43.4% cases. The thin highly permeable nature increases its susceptibility to allergens, making it distinct clinical entity. study aimed identify primary haptens...
Background/Objectives: Facial lesions, including lentigo maligna and melanoma (LM/LMM), both malignant, present significant diagnostic challenges due to their clinical similarity benign conditions. Although standard dermoscopy is a well-established tool for diagnosis, its inability reveal cellular-level details highlights the necessity of new magnified techniques. This study aimed assess role dermoscopy, high-magnification fluorescence-advanced videodermatoscopy (FAV) in diagnosing LM/LMM...
Background/Objectives: Basal cell carcinoma (BCC) is the most common malignancy, characterised by local invasiveness and potential for tissue destruction. Diagnosing BCC can be challenging, particularly less experienced dermatologists. Line-field confocal optical coherence tomography (LC-OCT), a new noninvasive technique, has become increasingly useful in clinical practice, allowing vivo imaging at cellular resolution. This study aimed to evaluate impact of 1 h structured training session on...
Tralokinumab is a monoclonal antibody selectively targeting IL-13, approved for moderate-to-severe atopic dermatitis (AD), which real-world data are scarce. This prospective, observational, multicentric study aimed to assess the long-term effectiveness and safety of tralokinumab in patients with AD setting. Primary outcomes included 50%, 75%, 90% improvement Eczema Area Severity Index score (EASI50, EASI75, EASI90, respectively) improvements Dermatology Life Quality (DLQI) at 1 year. A total...
Oral lichen planus (OLP) is a chronic inflammatory condition of uncertain etiology affecting oral mucosae by T-cell mediated inflammation. It affects between 1% and 3% the global population, predominantly middle-aged adults (50-60 years), with higher incidence in women. The immune response thought to target keratinocytes, leading cell death, particularly through CD8+ T lymphocytes. OLP manifests various clinical forms, such as reticular, papular, erosive, atrophic, reticular subtype being...
Background: Resilience is defined as the capacity to cope successfully with change or adversity. The aims of our study were investigate levels resilience in Italian healthcare professionals (HCPs) during Coronavirus disease 2019 (COVID-19) pandemic and identify potential predictors resilience. Methods: We performed a web-based survey HCPs (n = 1009) working hospitals COVID-19 pandemic. contained 14-item scale (RS14) questionnaires evaluate depression anxiety symptoms. Non-HCP individuals...
Basal cell carcinoma (BCC) is the most frequent malignancy in general population. To date, dermoscopy considered a key tool for diagnosis of BCC; nevertheless, line-field confocal optical coherence tomography (LC-OCT), new non-invasive technique, has become increasingly important clinical practice, allowing vivo imaging at cellular resolution. The present study aimed to investigate possible correlation between dermoscopic features BCC and their LC-OCT counterparts. In total, 100...
Psoriasis is an inflammatory skin disease with a chronic relapsing course and often-detrimental impact on patients' quality of life. Thanks to incredible advances in research over the past few decades, therapeutic armamentarium psoriasis now reasonably broad structured, several agents that have demonstrated successful long-term control this condition. However, there are still unfulfilled gaps resulting from inherent limitations existing therapies, which paved way for identification new...
Resilience is defined as "the capacity of individuals to cope successfully with significant change or adversity". The challenge posed by the COVID-19 pandemic may potentially represent an overwhelmingly stressful event for patients chronic diseases. Aim our study was investigate levels resilience in inflammatory arthritis living Emilia Romagna, third hardest-hit Italian region during ongoing pandemic. To this purpose, we developed a survey consisting four different sections assessing...