A5102856845- Epigenetics and DNA Methylation
- Retinal and Optic Conditions
- Cytokine Signaling Pathways and Interactions
- Inflammasome and immune disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Protist diversity and phylogeny
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Fetal and Pediatric Neurological Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Cancer-related molecular mechanisms research
- Eosinophilic Disorders and Syndromes
- Cancer Cells and Metastasis
- Microtubule and mitosis dynamics
- Renal and Vascular Pathologies
Istanbul Medeniyet University
2015-2024
Faculty (United Kingdom)
2015
Background: Cilioretinal arteries (CAs) represent enlargements of microscopic and early established collaterals formed via vasculogenesis between choroidal retinal circulations. We aimed to investigate whether genetic tendency thrombosis due well-known gene polymorphisms may induce CA in embryonic life.Methods: assessed plasminogen activator inhibitor-1 (PAI-1) 4G/5G, methylenetetrahydrofolatereductase (MTHFR), FACTOR V LEIDEN PROTHROMBIN on 130 patients [82/48 females/males; Median age: 57...
Purpose The MEFV gene encodes pyrin, a protein linked to increased severity of symptoms in Familial Mediterranean Fever (FMF). We consider that inflammation due variants would increase eye and damage aqueous humor regulation. present study is the first analysis investigating (E148Q) variant as marker protecting from glaucoma.
Abstract Background Our understanding of epigenetic modifications in the inner ear is very limited. Although regulation genes related to individual organ- and system-limited pathologies are generally expected be tissue-specific, DNA methylation patterns peripheral blood (PB) found associated with presence several diseases no typical hematological involvement. Here, we aimed investigate whether there a correlation between hearing-related genes’ promoter region PB samples non-syndromic...
Lentiginoses is a clinical feature in which lentigines are remarkably present large numbers or when they occur distinctive distribution on apparently normal skin. This entity may be congenital acquired and cover wide spectrum of diseases ranging from an isolated benign pigmentary disorder to numerous syndromes associated with molecular abnormalities.We 59-year-old female patient multiple first emerged 3 y ago concurrently policytemia vera. The had found positive for Janus Kinase-2 (JAK-2)...