- Single-cell and spatial transcriptomics
- Geotechnical Engineering and Soil Stabilization
- Sirtuins and Resveratrol in Medicine
- Innovations in Concrete and Construction Materials
- PARP inhibition in cancer therapy
- Vibration and Dynamic Analysis
- Ovarian cancer diagnosis and treatment
- Genomics and Chromatin Dynamics
- Geotechnical Engineering and Underground Structures
- Advanced biosensing and bioanalysis techniques
- RNA Research and Splicing
- Endoplasmic Reticulum Stress and Disease
- Autophagy in Disease and Therapy
Tianjin Research Institute of Electric Science (China)
2024
Zhejiang University
2024
Huazhong University of Science and Technology
2017
Tongji Hospital
2017
Abstract Single cell chromatin accessibility profiling and transcriptome sequencing are the most widely used technologies for single-cell genomics. Here, we present Microwell-seq3, a high-throughput facile platform high-sensitivity single-nucleus or full-length profiling. The method combines preindexing strategy penetrable chip-in-a-tube single nucleus loading DNA amplification therefore does not require specialized equipment. We Microwell-seq3 to profile in more than 200,000 nuclei ~50,000...