A5089767875- Advanced Radiotherapy Techniques
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Intracranial Aneurysms: Treatment and Complications
- Radiation Dose and Imaging
- Neurofibromatosis and Schwannoma Cases
- Anatomy and Medical Technology
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Neurological disorders and treatments
- Brain Metastases and Treatment
- Augmented Reality Applications
- Advanced X-ray and CT Imaging
- Advances in Oncology and Radiotherapy
- Facial Nerve Paralysis Treatment and Research
- Cerebrospinal fluid and hydrocephalus
- Surgical Simulation and Training
- Parkinson's Disease Mechanisms and Treatments
- Corporate Finance and Governance
- Ocular Oncology and Treatments
- Medical Image Segmentation Techniques
University of Florida
2016-2025
Vita-Salute San Raffaele University
2017-2024
IRCCS Ospedale San Raffaele
2024
Florida College
1999-2023
University of Toronto
2009-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2017
Pediatric Brain Tumor Foundation
2016
HealthEast Care System
2015
St. John's School
2015
Neurological Surgery
1989-2014
Abstract Objective Our aim was to compare in a prospective blinded study the cognitive and mood effects of subthalamic nucleus (STN) vs. globus pallidus interna (GPi) deep brain stimulation (DBS) Parkinson disease. Methods Fifty‐two subjects were randomized unilateral STN or GPi DBS. The co‐primary outcome measures Visual Analog Mood Scale, verbal fluency (semantic letter) at 7 months post‐DBS optimal setting compared pre‐DBS. At post‐DBS, tested four randomized/counterbalanced conditions (...
Abstract Chimeric antigen receptor (CAR) T-cell therapy targeting solid tumors has stagnated as a result of tumor heterogeneity, immunosuppressive microenvironments, and inadequate intratumoral T cell trafficking persistence. Early (≤3 days) presentation CAR cells post-treatment is superior predictor survival than peripheral Therefore, we have co-opted IL-8 release from to enhance through design for maximal antitumor activity in tumors. Here, demonstrate that receptor, CXCR1 or CXCR2,...
Abstract Despite the scientific and engineering challenges facing development of quantum computers, considerable progress is being made toward applying technology to commercial applications. In this article, we discuss solutions that some companies are already building using hardware. Framing these as examples combinatorics problems, illustrate their application in four industry verticals: cybersecurity, materials pharmaceuticals, banking finance, advanced manufacturing. While computers not...
Among the diverse areas of 3D printing, high-quality silicone printing is one least available and most restrictive. However, silicone-based components are integral to numerous advanced technologies everyday consumer products. We developed a technique that produces precise, accurate, strong, functional structures made from several commercially formulations. To achieve this level performance, we support material oil emulsion. This exhibits negligible interfacial tension against inks,...
Between May, 1988 and August, 1993, 158 patients with arteriovenous malformations (AVMs) were treated radiosurgically at the University of Florida. A mean dose 1560 cGy was directed to periphery lesions, which had a volume 9 cc (0.5 45.3 cc). One hundred thirty-nine these individuals one isocenter. The follow-up interval 33 months clinical information available on 153 patients. Patients followed until magnetic resonance (MR) studies suggested complete AVM thrombosis. An arteriogram then...
✓ Two hundred and one patients with arteriovenous malformations (AVMs) treated radiosurgically between May 1988 February 1995 are analyzed in this study. Twelve sustained a posttreatment hemorrhage during period. Pretreatment factors associated increased risk were identified 11 of these included arterial aneurysms, venous outflow obstruction, periventricular location, prior embolization, surgical treatment. A detailed statistical analysis, using both Poisson regression parametric survival...
Glutamine may be an essential dietary component, especially for the support of intestinal mucosal growth and function. This study evaluated effects a glutamine-enriched elemental diet, administered before whole-abdominal radiation on gut glutamine metabolism, morphometrics, bacterial translocation. Rats were randomized to receive nutritionally complete diet that was or glutamine-free 4 days. The animals then subjected single dose 1000 cGy x-radiation abdomen. After irradiation, all received...
✓ Between May, 1988, and August, 1991, 80 patients with arteriovenous malformations (AVM's) were treated radiosurgically at the University of Florida. A mean dose 1650 cGy was directed to periphery lesion, which almost always corresponded 80% isodose line. The lesion diameter 23 mm. Seventy-six one isocenter. Angiography, performed 1 year after radiosurgery in 41 48 eligible patients, revealed an overall complete thrombosis rate 39%. 1-year highest those relatively small AVM's. Angiography 2...
The healing effects of glutamine given orally for 8 days as a single amino acid nutrient after treatment with whole abdominal radiation (10 Gy) were studied. Rats received isonitrogenous and isovolumic diets containing 3% or glycine. Control rats not irradiated but identical diets. In animals, survival was 100% in animals receiving compared 45% Glutamine ingestion diminished bloody diarrhea the incidence bowel perforation. Arterial level higher diet, gut extraction (35% +/- 8% vs 12% 7%)...
The aim of this study was to identify factors associated with delayed cranial neuropathy following radiosurgery for vestibular schwannoma (VS or acoustic neuroma) and determine how such may be manipulated minimize the incidence radiosurgical complications while maintaining high rates tumor control.From July 1988 June 1998, 149 cases VS were treated using linear accelerator at University Florida. In each these cases, patient's brainstem contoured in 1-mm slices on original targeting images....
This study was undertaken to determine which factors were statistically predictive of radiological and clinical outcomes in the radiosurgical treatment arteriovenous malformations (AVMs).The computerized dosimetric data for 269 patients reviewed. The AVM nidus hand-contoured on successive enhanced computed tomographic slices through nidus, allow detailed determinations volume, target miss, normal brain tissue treated, dose conformality, gradient. In addition, a number patient factors,...
OBJECTIVE An increased extent of resection (EOR) has been shown to improve overall survival patients with glioblastoma (GBM) but the potential for causing a new postoperative neurological deficit. To investigate impact surgical morbidity on survival, authors performed retrospective analysis clinical data from GBM quantify deficit benefit achieved an EOR. METHODS The all who underwent at University Florida 2010 2015 imaging within 72 hours surgery were included in study. Retrospective was...
ABSTRACT Prior research documents a negative link between risk and executive holding of stock, but corresponding positive for options. We find similar relation non-executive stock. Our finding is consistent with the view that non-executives not only face significant incentives to reduce when they hold are also able affect corporate risk. While endogeneity cannot be ruled out fully, results battery tests suggest it plays limited role. A second robust result documented becomes more as...
Object. The aim of this study was to evaluate the causes treatment failure in patients with arteriovenous malformations (AVMs) who underwent radiosurgery, which is increasingly used as a method for selected, surgically high-risk AVMs. Unfortunately, radiosurgical fails small but significant percentage patients. In time period covered study, 72 attained angiographically confirmed cures after radiosurgery and 36 were retreated initial failed. Methods. Using computerized image fusion technique,...