A5035447277- Carbohydrate Chemistry and Synthesis
- Cancer therapeutics and mechanisms
- Biochemical and Molecular Research
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- HIV/AIDS drug development and treatment
- Antimicrobial Peptides and Activities
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Tuberculosis Research and Epidemiology
- Virus-based gene therapy research
- Synthesis and biological activity
- Chemical Synthesis and Analysis
- Microbial Natural Products and Biosynthesis
Malaghan Institute of Medical Research
2013-2016
Victoria University of Wellington
2013-2016
Victoria University
2014
A protecting-group-free synthetic strategy for the synthesis of piperidines has been explored. Key in is an I2-mediated carbamate annulation, which allows cyclization hydroxy-substituted alkenylamines into piperidines, pyrrolidines, and furans. In this work, four chiral scaffolds were compared contrasted, it was observed that with both d-galactose 2-deoxy-d-galactose as starting materials, transformations 1-deoxygalactonorjirimycin (DGJ) 4-epi-fagomine, respectively, could be achieved few...
Abstract Depending on the substrates ‐ which are derived from carbohydrates I 2 ‐mediated cyclization yields either furan or piperidine derivatives.