Providing patients with cancer who are undergoing systemic therapy useful information about symptom management is essential to prevent unnecessary deterioration of quality life.The aim was evaluate whether use an app for associated any change in patient life or health resources.Outpatients early stage breast receiving were recruited at the Institute Oncology Ljubljana, Slovenia. Patients received between December 2017 and March 2018 (control group) April September (intervention eligible. All...

<strong>Introduction:</strong> Research on models of integrated health care for hypertension and diabetes is one the priority issues in world. There a lack knowledge about how implemented practice. Our study assessed its implementation six areas: identification patients, treatment, education, self-management support, structured collaboration organisation care. <strong>Methods:</strong> This was mixed methods based triangulation method using quantitative qualitative data. It took place...

Because dogs tolerate conventional rectal temperature measurements poorly, a calibrated infrared thermometer was tested for assessing canine body surface temperature. Body of 204 estimated on various sites (digit, snout, axilla, eye, gum, inguinal region, and anal verge). Having as the gold standard, difference, Spearman's correlation coefficient, hyperthermia hypothermia detection sensitivity specificity, stress response score calculated each measurement site. Although considerably lower...

Patient empowerment is crucial for promoting and strengthening health. We aimed to assess patient diabetes-specific health-related quality of life (HRQoL) in adults with type 2 diabetes (T2D). A multi-centre, cross-sectional survey was conducted among T2D urban rural primary care settings Slovenia between April September 2023. The utilised convenience sampling included sociodemographic clinical data, the Diabetes Empowerment Scale (DES), Audit Diabetes-Dependent QoL (ADDQoL). study 289...

Abstract For cohorts with long‐term follow‐up, the number of years lost due to a certain disease yields measure simple and appealing interpretation. Recently, an overview methodology used for this goal has been published, two measures have proposed. In work, we consider third option that may be useful in settings which other are inappropriate. all three measures, survival given dataset is compared expected general population calculated using external mortality tables. We thoroughly analyze...

Integrated care of chronic patients improves quality their management, but there is scarce evidence its implementation in different healthcare settings. With this article, we wanted to determine the level integrated management T2D (diabetes) and HT (hypertension) three settings: Belgium, Slovenia, Cambodia.

<h2>Abstract</h2><h3>Background</h3> Early diagnosis of acute posttraumatic osteomyelitis (POM) is vital importance for avoiding devastating complications. Diagnosing POM difficult due to the lack a highly specific and sensitive test, such as in myocardial infarct, stroke intracranial bleeding. Serum inflammatory markers, C-reactive protein (CRP), procalcitonin (PCT), white blood cells (WBC) can support clinical findings but they are not able differentiate between response infection host...

During the first wave of COVID-19 pandemic in spring 2020, Slovenia was among least affected countries, but situation became drastically worse during second autumn 2020 with high numbers deaths per number inhabitants, ranking most countries. This true even though strict non-pharmaceutical interventions (NPIs) to control progression epidemic were being enforced. Using a semi-parametric Bayesian model developed for purpose this study, we explore if and how changes mobility, their timing...

Tumour microenvironment, composed of pro- and anti-tumour immune cells, affects cancer cells behaviour. We aimed to evaluate if tumour-infiltrating lymphocyte (TIL) density TILs subtypes in core biopsies at diagnosis breast patients could predict pathologic complete response (pCR; ypT0/is ypN0) from neoadjuvant systemic therapy (NST). The TIL were determined based on the proportions presumably (CD8+, CXCL13+) pro-tumour (PD-1+, FOXP3+) cells. A prospective, non-interventional study including...

The tumor microenvironment, composed of pro- and antitumor immune cells, affects cancer cell behavior. We aimed to evaluate whether tumor-infiltrating lymphocyte (TIL) density TIL subtypes in core biopsies at the diagnosis breast patients could predict a pathologic complete response (pCR; ypT0/is ypN0) from neoadjuvant systemic therapy (NST). were determined based on proportions presumably (CD8+, CXCL13+) protumor (PD-1+, FOXP3+) cells. A prospective, noninterventional study, including 171...

Background Augmented reality (AR) has benefits and feasibility in emergency medicine, especially the clinical care of patients, operating rooms inpatient facilities, education training providers, but current research on this topic is sparse. Objective The primary objective to evaluate short-term long-term effectiveness use AR treatment patients with anaphylactic shock. secondary objectives are safety shock, stress management process, determine experiences attitudes towards education. Methods...

Background Independence in daily activities is defined as the ability to perform functions related living, i.e. capacity of living independently community with little or no help from others. Objective We focused on non-attenders a subgroup patients whose health status not well known family practice teams. Our goal was estimate prevalence dependence and its severity level patients, determine factors that are associated occurrence dependence. Design Cross-sectional observational study....

The training of peer supporters is critical because the success entire support intervention depends on knowledge and experience that can share with other patients. objective this study was to evaluate pilot implementation a specialist nurse-led self-management programme for type 2 diabetes mellitus (T2DM) or without comorbid hypertension (HTN) at primary healthcare level in Slovenia, terms feasibility, acceptability, effectiveness. A prospective pre-post interventional conducted two...

There has been considerable interest in recent years quantifying the rate of unavoidable or so-called random cancers, as opposed to cancers linked environmental, genetic other factors. We propose a data-based approach estimate an upper limit this probability, based on analysis multiple registry data. The argument is that cumulative hazards for cannot exceed minimum reliable hazard observed across registries. Monte Carlo method identify and apply data nine different recorded by 423 compare...

e12626 Background: Morphological evaluation of tumor lymphocyte infiltration (TIL) in breast cancer (BC) is gaining importance the clinical setting, as it provides good prognostic information. Most institutions adhere to TIL working group guidelines for evaluating TIL, while having settle on an acceptable error margin due its subjective nature, which leads intra and inter-observer scoring discordance. We aimed analyze both at our institution, using experienced inexperienced examiners, with a...

Augmented reality (AR) is one of the emerging technologies today. It has potential to offer a novel approach medical training that supplements conventional methods with gamification and more interactive learning experience. In emergency medicine, AR benefits feasibility in clinical care patients, operating rooms inpatient facilities, education providers. To further explore role teaching management anaphylactic shock family doctors single blinded, randomized controlled trial will be...

<title>Abstract</title> <bold>Introduction</bold>: Training of peer supporters is critical because the success entire support intervention depends on knowledge and experience that can share with other patients. The objective was to evaluate pilot implementation a specialist nurse-led self-management training for type 2 diabetes (T2D), or without coexistent arterial hypertension (AH), in terms feasibility, acceptability, effectiveness. <bold>Methods</bold>: A prospective pre-post...

<sec> <title>BACKGROUND</title> Providing patients with cancer who are undergoing systemic therapy useful information about symptom management is essential to prevent unnecessary deterioration of quality life. </sec> <title>OBJECTIVE</title> The aim was evaluate whether use an app for associated any change in patient life or health resources. <title>METHODS</title> Outpatients early stage breast receiving were recruited at the Institute Oncology Ljubljana, Slovenia. Patients received between...

<sec> <title>BACKGROUND</title> Augmented reality (AR) has benefits and feasibility in emergency medicine, especially the clinical care of patients, operating rooms inpatient facilities, education training providers, but current research on this topic is sparse. </sec> <title>OBJECTIVE</title> The primary objective to evaluate short-term long-term effectiveness use AR treatment patients with anaphylactic shock. secondary objectives are safety shock, stress management process, determine...

Abstract This retrospective study was undertaken to investigate the association of relative dose intensity (RDI) with outcome Hodgkin lymphoma (HL) patients advanced stage disease receiving ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) and escalated BEACOPP regimen (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone). A total 114 HL treated between 2004 2013 were enrolled for evaluation. RDI calculations based on a Hryniuk's model. The...

The present retrospective study was undertaken to investigate the association of relative dose intensity (RDI) with outcome patients advanced stage Hodgkin lymphoma (HL) receiving ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) and escalated BEACOPP regimens (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone). A total 114 HL treated between 2004 2013 were enrolled for evaluation. variables overall survival (OS) progression-free (PFS) analysed...