A5063427149- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Toxoplasma gondii Research Studies
- Mosquito-borne diseases and control
- Cytomegalovirus and herpesvirus research
- Insect Pest Control Strategies
- Insect and Pesticide Research
- Plant Parasitism and Resistance
- Herpesvirus Infections and Treatments
- Toxin Mechanisms and Immunotoxins
- Parasitic Infections and Diagnostics
- Peptidase Inhibition and Analysis
- Biochemical and Molecular Research
- Malaria Research and Control
- vaccines and immunoinformatics approaches
- Cellular transport and secretion
- Animal Virus Infections Studies
- Coccidia and coccidiosis research
- Viral gastroenteritis research and epidemiology
- HIV/AIDS drug development and treatment
- Autophagy in Disease and Therapy
- Pneumocystis jirovecii pneumonia detection and treatment
- Adenosine and Purinergic Signaling
- Insect Resistance and Genetics
Jiangsu Agri-animal Husbandry Vocational College
2023-2025
Obihiro University of Agriculture and Veterinary Medicine
2010-2023
Harbin Veterinary Research Institute
2016-2023
Chinese Academy of Agricultural Sciences
2016-2023
Yanbian University
2009
Academy of Military Medical Sciences
2008
The University of Texas Health Science Center at Houston
1995
Dermal fibroblasts from a 13-yr-old boy with isolated skeletal features of the Marfan syndrome were used to study fibrillin synthesis and processing. Only one half secreted profibrillin was proteolytically processed outside cell deposited into extracellular matrix. Electron microscopic examination rotary shadowed microfibrils made by proband's indistinguishable control cells. Sequencing FBN1 gene revealed heterozygous C T transition at nucleotide 8176 resulting in substitution tryptophan for...
Infections with Babesia bovis, bigemina, Theileria species and Anaplasma marginale are endemic in Kenya yet there is a lack of adequate information on their genotypes. This study established the genetic diversities above tick-borne hemoparasites infecting cattle Kenya.Nested PCR sequencing were used to determine prevalence diversity parasites 192 blood samples collected from Ngong Machakos farms. B. bovis spherical body protein 4, bigemina rhoptry-associated 1a, A. major surface 5, spp. 18S...
An expanded library of murine monoclonal antibodies (MAbs) was generated by infecting BALB/C mice with the Therien strain rubella virus (RV) and selecting secreting hybrids enzyme-linked immunosorbent assay (ELISA) using purified virion targets. A panel plasmids containing specified RV cDNA fragments also constructed a variety strategies pGE374- pGE374-derived expression vectors. Hybrid RecA-RV-beta-galactosidase (LacZ)- or RecA-RV-truncated LacZ-containing proteins collectively representing...
Ovine theileriosis is a tick-borne disease that restricts the development of small ruminant husbandry in northern China. In this study, we report on molecular epidemiological survey ovine Theileria spp. 198 blood samples taken from sheep The DNA were screened by nested polymerase chain reaction (PCR) targeting 18S rRNA gene prevalence Yanji, Nongan, Longjing, Toudao and Jinchang was 80%, 40%, 37%, 24% 32%, respectively. sequencing analyses approved present T. orientalis and/or luwenshuni...
Considering the scarce information on occurrences of Toxoplasma gondii and Neospora caninum in domestic animals from Turkey, aim this study was to investigate seroprevalence these parasite infections cattle, horses, sheep, goats dogs Turkey. The specific antibodies against T. N. were detected by iELISAs based recombinant TgSAG2 or NcSAG1 a total 2,039 serum samples eleven provinces. 46.3%, 4.0%, 20.0%, 12.9% 19.8%, that 0.3%, 7.4%, 2.1%, 3.2% 16.6% dogs, respectively. These results indicated...
Vesicular trafficking is a fundamental cellular process involved in material transport eukaryotes, but the diversity of intracellular compartments has prevented researchers from obtaining clear understanding specific functions vesicular factors, including SNAREs, tethers, and Rab GTPases,
The H9N2 avian influenza virus is widely disseminated in poultry and poses a zoonotic threat, despite vaccination efforts. Mutations at residue 198 of hemagglutinin (HA) are critical for antigenic variation receptor-binding specificity, but the underlying molecular mechanisms remain unclear. This study explores by which mutations HA site affect antigenicity, receptor binding affinity virus. Using sequence A/Chicken/Jiangsu/WJ57/2012 strain, we constructed recombinant viruses, including...
Small ruminant breeding plays a vital role in livestock farming Türkiye but is adversely affected by many infectious pathogens, including Toxoplasma (T.) gondii and Neospora (N.) caninum. This study aimed to investigate the seroprevalence of ovine toxoplasmosis neosporosis sheep with varying abortion histories Central Anatolia Region Türkiye. Two hundred forty-three blood samples were taken from different farms, 115 these problems, others herds no history. Recombinant TgSAG2 NcSAG1-based...
In the present study, we examined contributions of macrophages to outcome infection with Babesia microti, etiological agent human and rodent babesiosis, in BALB/c mice. Mice were treated clodronate liposome at different times during course B. microti order deplete macrophages. Notably, a depletion host early acute phases caused significant elevation parasitemia associated remarkable mortality The resolving latent resulted an immediate temporal exacerbation coupled Reconstituting...
The continuously evolving PRRSV has been plaguing pig farms worldwide for over 30 years, with conventional vaccines suffering from insufficient protection and biosecurity risks. To address these challenges, we identified 10 PRRSV-specific CTL epitopes through enzyme-linked immunospot assay (ELISPOT) constructed a multi-epitope peptide (PTE) by linking them in tandem. This PTE was then fused modified porcine Fc molecule to create the recombinant protein pFc-PTE. Our findings indicate that...