A5081222097- Cannabis and Cannabinoid Research
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Neurotransmitter Receptor Influence on Behavior
- Digital Mental Health Interventions
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Neural dynamics and brain function
- Substance Abuse Treatment and Outcomes
- Healthcare professionals’ stress and burnout
- Tryptophan and brain disorders
- Homelessness and Social Issues
- Psychedelics and Drug Studies
- Mental Health and Psychiatry
- Alcohol Consumption and Health Effects
- Sleep and Wakefulness Research
- Workplace Health and Well-being
- Health, Medicine and Society
- COVID-19 and Mental Health
- Sleep and Work-Related Fatigue
- Immune Cell Function and Interaction
- Prenatal Substance Exposure Effects
Centre Hospitalier de l’Université de Montréal
2020-2024
Université de Montréal
2020-2024
Centre Hospitalier Universitaire Sainte-Justine
2022
Institut Universitaire en Santé Mentale de Québec
2017
ABSTRACT Background and Aims Cocaine use disorder (CUD) is a significant public health concern for which no efficacious pharmacological interventions are available. Cannabidiol (CBD) has attracted considerable interest as promising treatment addiction. This study tested CBD efficacy reducing craving preventing relapse in people with CUD. Design Single‐site double‐blind randomized controlled superiority trial comparing placebo. Setting Participants Centre Hospitalier de l'Université Montréal,...
Objectives Individuals with a cocaine use disorder (CUD) are more likely to present anxiety, which in turn negatively impacts substance outcomes. Some evidence suggests that cannabidiol (CBD) presents anxiolytic properties and could be treatment for disorders. This study explores CBD’s effect on stress biomarker (cortisol) anxiety symptoms people CUD. Methods Exploratory analyses were conducted using data from randomized, double-blind, placebo-controlled trial evaluating efficacy treat We...
Cocaine use disorder (CUD) is associated with various cognitive deficits that impede patients' functionality, prognosis and therapeutic outcomes. New pharmacological treatments for CUD could improve cognition are needed.To explore whether cannabidiol (CBD) superior to placebo functioning in individuals CUD.We conducted an exploratory analysis of a single site, randomized, double-blind, placebo-controlled trial evaluating CBD's efficacy reducing craving, cocaine relapse CUD. Seventy-eight...
The restrictions implemented around the world to contain spread of coronavirus disease 2019 (COVID-19) impact workers. Emotional distress and maladaptive behaviors such as alcohol misuse are expected, particularly in vulnerable groups front-line health In present study, we examined if consumption Quebec workers changed during confinement COVID-19 pandemic, whether healthcare reported specific patterns changes.Data were obtained from an anonymous online survey conducted among adult aged ⩾18...
Background The persistence of cannabis use disorder (CUD) in young adults with first-episode psychosis (FEP) is associated poor clinical and functional outcomes. Face-to-face psychological interventions are effective treating CUD. However, their early intervention services (EISs) for inconsistent because barriers, including high workload heterogeneity training clinicians lack motivation treatment among patients. Tailoring new technology-based (TBPIs) to overcome these barriers necessary...
Abstract Our objective was to assess the generalizability, across sites and cognitive contexts, of schizophrenia classification based on functional brain connectivity. We tested different training-test scenarios combining fMRI data from 191 patients matched healthy controls obtained at 6 scanning under task conditions. Diagnosis accuracy generalized well a novel site context provided multiple were used for classifier training. By contrast, lower achieved when single distinct These findings...
Cannabis is consumed by more than 182 million people worldwide [1] and research on cannabinoids booming, with the potential of supporting public health initiatives that promote safer cannabis use. It has been proposed cannabidiol (CBD) can guard against adverse effects tetrahydrocannabinol (THC), which led governmental academic bodies to recommend use products high CBD : THC ratios (e.g. [2]). We believe evidence for this weak. Observational studies have demonstrated a possible protective...
Cannabidiol (CBD) has been proposed to have a therapeutic potential over wide range of neuropsychiatric disorders, including substance use disorders. Pre-clinical evidence suggests that CBD can increase anandamide (AEA) plasma concentration, possibly mediating some its properties. Whether exerts such an effect on AEA in individuals with cocaine disorder (CUD) remains unknown.
Background: Previous work provided conversion equations for overall indices of positive and negative symptomatology between the two most widely used scales to assess symptom severity in schizophrenia, namely Positive Negative Syndrome Scale (PANSS) Scales Assessment Positive/Negative Symptoms (SAPS/SANS). Our objective was provide such subdomains order better account diversity profiles schizophrenia.Method: assessed using both PANSS SAPS/SANS 205 patients with schizophrenia. Two exploratory...
Abstract Background: Previous work provided conversion equations for overall indices of positive and negative symptomatology between the two most widely used scales to assess symptom severity in schizophrenia, namely Positive Negative Syndrome Scale (PANSS) Scales Assessment Positive/Negative Symptoms (SAPS/SANS). Our objective was provide such subdomains order better account diversity profiles schizophrenia. Method: assessed using both PANSS SAPS/SANS 205 patients with Two exploratory...
<sec> <title>BACKGROUND</title> The persistence of cannabis use disorder (CUD) in young adults with first-episode psychosis (FEP) is associated poor clinical and functional outcomes. Face-to-face psychological interventions are effective treating CUD. However, their early intervention services (EISs) for inconsistent because barriers, including high workload heterogeneity training clinicians lack motivation treatment among patients. Tailoring new technology-based (TBPIs) to overcome these...