Mitsuhiro Koyama

ORCID: 0000-0001-8532-9478
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Research Areas
  • Medical Imaging Techniques and Applications
  • Advanced X-ray and CT Imaging
  • Radiation Dose and Imaging
  • Lung Cancer Diagnosis and Treatment
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Medical Imaging and Pathology Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Atomic and Subatomic Physics Research
  • Myasthenia Gravis and Thymoma
  • AI in cancer detection
  • Occupational and environmental lung diseases
  • Microfluidic and Bio-sensing Technologies
  • Electrowetting and Microfluidic Technologies
  • COVID-19 diagnosis using AI
  • Esophageal Cancer Research and Treatment
  • Advanced MRI Techniques and Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Bladder and Urothelial Cancer Treatments
  • Tracheal and airway disorders
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Meningioma and schwannoma management
  • MRI in cancer diagnosis
  • Pleural and Pulmonary Diseases
  • Systemic Sclerosis and Related Diseases
  • Radiology practices and education

Osaka University of Pharmaceutical Sciences
2024-2025

Ikeda Municipal Hospital
2025

Osaka Medical and Pharmaceutical University
2012-2021

National Defense Medical College
2016

National Defense Medical College Hospital
2016

Osaka University
2001-2013

Osaka University Hospital
2013

Osaka Rosai Hospital
2013

Nara Medical University
2012

Nagoya University
2007-2009

To characterize thin-section computed tomographic (CT) findings of pathologic subgroups nonspecific interstitial pneumonia (NIP) in a sizeable number patients.The study included 55 cases pathologically proven NIP. The were categorized histologically into four grades: grade 1, inflammation without fibrosis (n = 6); 2, predominating over 16); 3, 5); and 4, only 28). Two independent observers evaluated the presence, extent, distribution various CT findings. Thin-section histologic grades...

10.1148/radiol.2251011555 article EN Radiology 2002-10-01

The objective of this study was to determine whether the various chronic cystic lung diseases can be differentiated on basis pattern and distribution abnormalities high-resolution CT.High-resolution CT scans in 92 patients with (18 pulmonary Langerhans cell histiocytosis, 18 lymphangioleiomyomatosis, 17 usual interstitial pneumonia, 16 lymphocytic 15 emphysema, eight desquamative pneumonia or respiratory bronchiolitis disease) were retrospectively assessed by two independent observers...

10.2214/ajr.180.3.1800827 article EN American Journal of Roentgenology 2003-03-01

Our purpose was to assess the CT features of various subtypes thymic epithelial neoplasms on basis 1999 World Health Organization classification.Thymic in 53 patients who underwent thymectomy were retrospectively assessed histologically according classification. Type A and B correspond thymomas type C, carcinoma. The study included four with A, 14 AB, nine B1, B2, B3, eight C tumors. Two observers independently scans without knowledge histologic findings.Type tumors more likely have smooth...

10.2214/ajr.179.4.1790881 article EN American Journal of Roentgenology 2002-10-01

The aim of the present study was to assess evolution various computed tomographic (CT) findings lymphocytic interstitial pneumonia (LIP) with determination potentially reversible or irreversible features. included 14 patients biopsy-proved LIP who had serial thin-section CT examination 4 82 months (median 13 months) apart. Initial and follow-up scans were evaluated independently then directly compared each other by two observers. main parenchymal abnormalities on initial scan consisted...

10.1097/00005382-200007000-00002 article EN Journal of Thoracic Imaging 2000-07-01

To compare lung nodule detection performance (LNDP) in computed tomography (CT) with adaptive iterative dose reduction using three dimensional processing (AIDR3D) between ultra-low CT (ULDCT) and low (LDCT).This was part of the Area-detector Computed Tomography for Investigation Thoracic Diseases (ACTIve) Study, a multicenter research project being conducted Japan. Institutional Review Board approved this study informed consent obtained. Eighty-three subjects (body mass index, 23.3 ± 3.2)...

10.1016/j.ejrad.2015.03.012 article EN cc-by-nc-nd European Journal of Radiology 2015-04-06

This prospective study was undertaken to establish a novel management algorithm using new indicators decide the type of lung resection for small peripheral lesions.Inclusion criteria were: (1) <or=20mm lesion(s) and (2) absence significant lymph node swelling on preoperative CT. Along with conventional criteria, percentage ground-glass opacity (GGO) (>or=50% as GGO <50% solid type) high-resolution CT scan employed. In accordance such indicators, wide wedge (WWR), segmentectomy or lobectomy...

10.1016/j.ejcts.2008.07.044 article EN European Journal of Cardio-Thoracic Surgery 2008-08-29

The objective of this study was to describe the pulmonary abnormalities on high-resolution computed tomography (CT) in patients with mixed connective tissue disease (MCTD). included 41 who met diagnostic criteria for MCTD and showed abnormal findings CT. presence, extent, distribution various CT were evaluated. predominant areas ground-glass attenuation (n = 41), subpleural micronodules 40), nonseptal linear opacities 32). Other common peripheral predominance lower lobe 39), intralobular...

10.1097/00005382-200104000-00005 article EN Journal of Thoracic Imaging 2001-04-01

Comparison of Quality Multiplanar Reconstructions and Direct Coronal Multidetector CT Scans the LungOsamu Honda1, Takeshi Johkoh1, Shuji Yamamoto2, Mitsuhiro Koyama1, Noriyuki Tomiyama1, Takenori Kozuka1, Seiki Hamada1, Naoki Mihara1, Hironobu Nakamura1 Nestor L. Müller3Audio Available | Share

10.2214/ajr.179.4.1790875 article EN American Journal of Roentgenology 2002-10-01

Objective To assess the advantages of Adaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR3D) for image quality improvement and dose reduction chest computed tomography (CT). Methods Institutional Review Boards approved this study informed consent was obtained. Eighty-eight subjects underwent CT at five institutions identical scanners protocols. During a single visit, each subject scanned different tube currents: 240, 120, 60 mA. Scan data were converted to images...

10.1371/journal.pone.0105735 article EN cc-by PLoS ONE 2014-08-25

Background/Objectives: This study compared chest high-resolution computed tomography (HRCT) findings between patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive and antibody-negative progressive pulmonary fibrosis (PPF) polymyositis/dermatomyositis (PM/DM). Methods: Of the 85 PM/DM-interstitial lung disease (ILD), 17 were anti-MDA5 antibody-positive, 68 antibody-negative. Among these, 9 cases met criteria for PPF enrolled in study. The HRCT duration from...

10.3390/jcm14051601 article EN Journal of Clinical Medicine 2025-02-27

Objective: To determine whether the subtypes of nonspecific interstitial pneumonia (NSIP) could be differentiated from other idiopathic pneumonias (IIPs) on basis findings high-resolution computed tomography (CT). Methods: Two observers evaluated CT in 90 patients with IIPs. The included 36 NSIP, 11 usual (UIP), 8 cryptogenic organizing (COP), 10 acute (AIP), 14 desquamative (DIP) or respiratory bronchiolitis-associated lung disease (RB-ILD), and lymphoid (LIP). NSIP cases were subdivided...

10.1097/01.rct.0000182853.90520.84 article EN Journal of Computer Assisted Tomography 2005-11-01

We investigated the image quality of multiplanar reconstruction (MPR) using adaptive statistical iterative (ASIR).Inflated and fixed lungs were scanned with a garnet detector CT in high-resolution mode (HR mode) or non-high-resolution (HR) mode, MPR images then reconstructed. Observers compared 15 ASIR (40%) (80%) those (0%), assessed visual five-point scale (1, definitely inferior; 5, superior), particular emphasis on normal pulmonary structures, artefacts, noise overall quality.The mean...

10.1259/bjr/57998586 article EN British Journal of Radiology 2011-03-17

Abstract Background Redundant blood supply by angiogenesis is a great advantage for the continuous growth of solid tumors. However, with chemotherapy (ChT), it can be disadvantageous due to increased drug delivery. An objective, reproducible, and non‐invasive method evaluating tumor offered perfusion CT. Methods Fifty‐five advanced esophageal cancers (95% squamous cell carcinomas) were evaluated hemodynamic parameters, including flow (BF), volume (BV), mean transit time (MTT) primary CT...

10.1002/jso.20820 article EN Journal of Surgical Oncology 2007-04-20

PURPOSE: To evaluate the usefulness of a commercially available computer-aided diagnosis (CAD) system that incorporates temporal subtraction for detection solitary pulmonary nodules on chest radiographs by readers with different levels experience. MATERIALS AND METHODS: Sixty pairs in 30 patients newly detected and normal cases, all confirmed serial computed tomography (CT), were obtained from screen-film or digital radiographic systems digitized (spatial resolution, 0.171 mm/pixel)....

10.1148/radiol.2233010957 article EN Radiology 2002-06-01

To evaluate the image quality of both standard- and reduced-dose computed tomography (CT) by comparing multidetector CT with garnet-based detectors conventional detectors.The study was approved internal ethics review board. Informed consent obtained. Eleven cadaveric lungs inflated fixed using Heitzman method were scanned detectors. Tube current 400 mA for standard-dose 10 CT, voltage 120 kVp. Either normal scan mode 984 views (conventional detectors) or high-resolution 2496 used. Image at...

10.1148/radiol.10091010 article EN Radiology 2010-05-25

The purpose of this study was to evaluate the accuracy temporal subtraction with a commercially available computer-assisted diagnosis system for detection multifocal hazy pulmonary opacities on chest radiographs, which are sometimes difficult detect directly radiographs.Thirty healthy patients and 30 new that were confirmed by serial CT examinations evaluated without images. Chest radiographs taken from either film-screen or digital radiography images digitized spatial resolution 0.171 mm...

10.2214/ajr.179.2.1790467 article EN American Journal of Roentgenology 2002-08-01

To evaluate CT findings of pulmonary alveolar microlithiasis and correlate the with pathologic findings.The study included 10 patients pathologically proven microlithiasis. Two independent observers evaluated presence, extent distribution findings. were compared those at autopsy in two transbronchial biopsy eight patients.All had a myriad calcified nodules measuring approximately 1 mm diameter. Close apposition resulted areas ground-glass attenuation consolidation, which predominant...

10.4081/monaldi.2005.659 article EN cc-by-nc Monaldi Archives for Chest Disease 2005-03-30

The development of diagnostic technology has led to detection an increasing number small pulmonary nodules (SPNs), which can be difficult locate intraoperatively. Here, we report our experience performing single-stage lipiodol localization and surgical resection in a hybrid operating room (OR).Between June 2016 August 2017, 30 patients with 32 SPNs underwent sliding gantry-based multidetector computed tomography (MDCT)-guided marking followed by video-assisted thoracoscopic surgery (VATS)...

10.21037/jtd.2018.05.28 article EN cc-by-nc-nd Journal of Thoracic Disease 2018-05-01

75歳以上101歳までの非痴呆高齢者15例と非痴呆成人者10例の剖検大脳について, アルミニウム量と神経細胞の形態学的変化, 特に神経原線維変化と老人斑の形成との関連性について検討し以下の結果を得た.1. 非痴呆成人者例の大脳組織中のアルミニウム量は海馬回では, 14.4±1.39ppb, 前頭葉皮質では20.4±2.54ppbと微量であった. 非痴呆高齢者例の海馬回では401.7±60.05ppb, 前頭葉皮質では373.29±72.35ppbの値を示した. 非痴呆高齢者例の脳内に海馬回で28倍, 前頭葉皮質では19倍と非痴呆成人例に比べ顕著に増量を示した.2. Morin 法によるアルミニウムの組織化学的検索では, 非痴呆高齢者脳内の神経原線維変化や老人斑内の amyloid core の一部に蛍光反応を認めた. 正常部位では毛細血管壁, 血管周囲の支持組織, 星状膠細胞の核内, 神経細胞の核および核小体の一部に蛍光反応を認めた. しかし, 非痴呆成人例には, アルミニウムは認められなかった.3. 形態学的に老人斑は,...

10.3143/geriatrics.31.950 article EN Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics 1994-01-01

OBJECTIVE. The aim of this study was to evaluate the image quality and diagnostic efficacy multidetector high-resolution CT (HRCT) by comparing it with single-detector HRCT noise artifact images a phantom. SUBJECTS AND METHODS. Multidetector six parameters were performed on cadaveric lungs. evaluated in comparison those HRCT. A phantom scanned, investigated. RESULTS. axial 1.25 mm × 4i (four per gantry rotation) mode equal that other modes worse than high-quality (pitch, 3:1) high-speed 6:1)...

10.2214/ajr.177.4.1770875 article EN American Journal of Roentgenology 2001-10-01
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