A5007184789- Chemical Synthesis and Reactions
- Asymmetric Hydrogenation and Catalysis
- Oxidative Organic Chemistry Reactions
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Analysis
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Catalytic Cross-Coupling Reactions
- Inorganic and Organometallic Chemistry
- Synthesis and Catalytic Reactions
- Organometallic Complex Synthesis and Catalysis
- Cyclopropane Reaction Mechanisms
- Fluorine in Organic Chemistry
- Chemical Reactions and Isotopes
- Metal-Catalyzed Oxygenation Mechanisms
- Porphyrin and Phthalocyanine Chemistry
- Coordination Chemistry and Organometallics
- Catalysis and Oxidation Reactions
- Organic Chemistry Cycloaddition Reactions
- Sulfur-Based Synthesis Techniques
- Vanadium and Halogenation Chemistry
- Catalytic Alkyne Reactions
- Polyoxometalates: Synthesis and Applications
- Advanced Synthetic Organic Chemistry
- Synthesis and Reactions of Organic Compounds
Osaka University
2006-2021
Okayama University of Science
2007-2016
Okayama University
2002-2015
Shanghai Institute of Organic Chemistry
2014
Asahi Kasei (Japan)
2013
Thieme Medical Publishers (Germany)
2005
Kochi University of Technology
2003
GTx (United States)
2000
Osaka Health Science University
1963
Abstract The metabolism of amines is governed by a variety enzymes such as amine oxidase, flavoenzyme, and cytochrome P‐450. A wide compounds are produced ammonia alkaloids in selective clean oxidation reactions that proceed under mild reaction conditions. Simulation the functions these with simple transition metal complex catalysts may lead to discovery biomimetic, catalytic oxidations related compounds. Indeed, catalyzed have been found high efficiency. first section this review discusses...
RuCl3-catalyzed oxidative cyanation of tertiary amines with sodium cyanide under molecular oxygen (1 atm) at 60 °C gives the corresponding α-aminonitriles, which are versatile synthetic intermediates various compounds such as amino acids and unsymmetrical 1,2-diamines, in excellent yields. This reaction is clean should be an environmentally benign useful process.
Ruthenium-catalyzed oxidative cyanation of tertiary amines with molecular oxygen in the presence sodium cyanide and acetic acid gives corresponding alpha-aminonitriles, which are highly useful intermediates for organic synthesis. The reaction is first demonstration direct sp(3) C-H bond activation alpha to nitrogen followed by carbon-carbon formation under aerobic oxidation conditions. catalytic seems proceed (i) alpha-C-H ruthenium catalyst give an iminium ion/ruthenium hydride...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective synthesis of alkenes and alkenyl sulfides from halides using palladium ruthenium catalystsShunichi Murahashi, Masaaki Yamamura, Kenichi Yanagisawa, Nobuaki Mita, Kaoru KondoCite this: J. Org. Chem. 1979, 44, 14, 2408–2417Publication Date (Print):July 1, 1979Publication History Published online1 May 2002Published inissue 1 July 1979https://pubs.acs.org/doi/10.1021/jo01328a016https://doi.org/10.1021/jo01328a016research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRuthenium-catalyzed oxidative transformation of alcohols and aldehydes to esters lactonesShunichi Murahashi, Takeshi Naota, Keiichiro Ito, Yoshihiro Maeda, Hiroshi TakiCite this: J. Org. Chem. 1987, 52, 19, 4319–4327Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://pubs.acs.org/doi/10.1021/jo00228a032https://doi.org/10.1021/jo00228a032research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTungstate-catalyzed oxidation of secondary amines to nitrones. .alpha.-Substitution via nitronesShunichi Murahashi, Hitoshi Mitsui, Tatsuki Shiota, Tomoyasu Tsuda, and Shoji WatanabeCite this: J. Org. Chem. 1990, 55, 6, 1736–1744Publication Date (Print):March 1, 1990Publication History Published online1 May 2002Published inissue 1 March 1990https://pubs.acs.org/doi/10.1021/jo00293a013https://doi.org/10.1021/jo00293a013research-articleACS...
Versatile intermediates for the synthesis of N-aryl-α-amino acids and N,N-disubstituted 1,2-diamines can now be synthesized with high efficiency by ruthenium-catalyzed oxidative cyanation tertiary amines. The use hydrogen peroxide as an oxidant in presence NaCN/AcOH or HCN provides corresponding α-aminonitriles (see reaction).
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCopper(I)-Catalyzed Amination of Propargyl Esters. Selective Synthesis Propargylamines, 1-Alken-3-ylamines, and (Z)-AllylaminesYasushi Imada, Mari Yuasa, Ishin Nakamura, Shun-Ichi MurahashiCite this: J. Org. Chem. 1994, 59, 9, 2282–2284Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 1994https://pubs.acs.org/doi/10.1021/jo00088a004https://doi.org/10.1021/jo00088a004research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew aspects of oxypalladation alkenesTakahiro Hosokawa and Shunichi MurahashiCite this: Acc. Chem. Res. 1990, 23, 2, 49–54Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February 1990https://pubs.acs.org/doi/10.1021/ar00170a006https://doi.org/10.1021/ar00170a006research-articleACS PublicationsRequest reuse permissionsArticle Views1380Altmetric-Citations199LEARN ABOUT THESE METRICSArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRuthenium-catalyzed cytochrome P-450 type oxidation of tertiary amines with alkyl hydroperoxidesShunichi. Murahashi, Takeshi. Naota, and Koichi. YonemuraCite this: J. Am. Chem. Soc. 1988, 110, 24, 8256–8258Publication Date (Print):November 1, 1988Publication History Published online1 May 2002Published inissue 1 November 1988https://pubs.acs.org/doi/10.1021/ja00232a060https://doi.org/10.1021/ja00232a060research-articleACS PublicationsRequest reuse...
Novel biomimetic, aerobic oxidation with an organocatalyst was performed. The oxidations of organic substrates such as sulfides, secondary amines, N-hydroxylamines, and tertiary amines molecular oxygen (1 atm) or even in air the presence 5-ethyl-3-methyllumiflavinium perchlorate catalyst hydrazine monohydrate 2,2,2-trifluoroethanol occur highly efficiently to give corresponding oxidized compounds excellent yields along water nitrogen, which are environmentally benign. TON sulfides amounts 19 000.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRuthenium-catalyzed oxidation of amides and lactams with peroxidesShunichi Murahashi, Takeshi Naota, Toshiyuki Kuwabara, Takao Saito, Hidenori Kumobayashi, Susumu AkutagawaCite this: J. Am. Chem. Soc. 1990, 112, 21, 7820–7822Publication Date (Print):October 1, 1990Publication History Published online1 May 2002Published inissue 1 October 1990https://pubs.acs.org/doi/10.1021/ja00177a067https://doi.org/10.1021/ja00177a067research-articleACS...
The chiral organocatalyst bisflavin 1 catalyzes the asymmetric Baeyer–Villiger reaction of cyclobutanones with H2O2 (see scheme). corresponding lactones are obtained up to 74 % ee.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPalladium(0)-catalyzed azidation of allyl esters. Selective synthesis azides, primary allylamines, and related compoundsShunichi Murahashi, Yuki Taniguchi, Yasushi Imada, Yoshio TanigawaCite this: J. Org. Chem. 1989, 54, 14, 3292–3303Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/jo00275a011https://doi.org/10.1021/jo00275a011research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic alkyl group exchange reaction of primary and secondary aminesShunichi Murahashi, Noriaki Yoshimura, Tatsuo Tsumiyama, Takeyuki KojimaCite this: J. Am. Chem. Soc. 1983, 105, 15, 5002–5011Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/ja00353a025https://doi.org/10.1021/ja00353a025research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPalladium(II)-catalyzed asymmetric oxidative cyclization of 2-allylphenols in the presence copper(II) acetate and molecular oxygen. Study catalysis Wacker-type oxidationTakahiro Hosokawa, Tetsuyuki Uno, Shiro Inui, Shunichi MurahashiCite this: J. Am. Chem. Soc. 1981, 103, 9, 2318–2323Publication Date (Print):May 1, 1981Publication History Published online1 May 2002Published inissue 1...