- Health Systems, Economic Evaluations, Quality of Life
- Peptidase Inhibition and Analysis
- Pharmaceutical Economics and Policy
- Helicobacter pylori-related gastroenterology studies
- Lipoproteins and Cardiovascular Health
- Pancreatitis Pathology and Treatment
- Eosinophilic Esophagitis
- Veterinary medicine and infectious diseases
- Intestinal and Peritoneal Adhesions
- Pediatric Hepatobiliary Diseases and Treatments
- Gastroesophageal reflux and treatments
- Aortic Thrombus and Embolism
- Vitamin K Research Studies
- Gestational Trophoblastic Disease Studies
- Vitamin D Research Studies
- Pancreatic function and diabetes
Target (United States)
2024
Amgen (United States)
2024
AbbVie (United States)
2024
Nanjing Jiangning Hospital
2023
Women's Hospital, School of Medicine, Zhejiang University
2017
Program for Appropriate Technology in Health
2016
Saint Louis University
2016
Racecadotril (acetorphan) is a neutral endopeptidase (NEP) inhibitor with known antidiarrheal activity in animals and humans; however, humans, it suffers from shortcomings that might be improved newer drugs this class have progressed to the clinic for nonenteric disease indications. To identify potentially superior NEP inhibitors immediate clinical utility diarrhea treatment, we compared their efficacy pharmacologic properties rat intestinal hypersecretion model. seven other clinical-stage...
Objective: To evaluate the effect of endoplasmic reticulum stress in trophocytes, patients with intrahepatic cholestasis pregnancy (ICP). Methods: Sixty-one pregnant women who were hospitalized Women's Hospital, School Medicine, Zhejiang University from January to December 2015 recruited. Thirty-one diagnosed as ICP defined group and 30 healthy control group. The localization expression intensity glucose regulated protein 78 (GRP-78) placental tissues detected by immunohistochemistry...
Initiation of proprotein convertase subtilisin/kexin type 9 monoclonal antibody (PCSK9 mAb) for lipid-lowering following myocardial infarction (MI) is likely affected by patients' prognostic factors, potentially leading to bias when comparing real-world treatment effects.
The 2013 ACC/AHA cholesterol treatment guidelines removed the recommendation to treat adults at risk of cardiovascular disease goal levels low-density lipoprotein (LDL-C). We anticipated that frequency LDL-C testing in clinical practice would decline as a result. To test this hypothesis, we evaluated before and after guideline release.We used MarketScan® Commercial Medicare Supplemental claims data (1/1/2007-12/31/2016) identify four cohorts: 1) statin initiators (any intensity), 2)...
The effects of triple antibiotic therapy plus probiotics on Helicobacter pylori-induced peptic ulcers were assessed. To this end, patients diagnosed with divided into control and treatment groups. group received standardized (rabeprazole sodium, amoxicillin, clarithromycin) therapy, whereas the also Compound Eosinophil-Lactobacillus tablets for 14 consecutive days. outcomes (Helicobacter pylori eradication rate, expression levels serum procalcitonin, high-sensitivity C-reactive protein,...